| 628633 | Mafk | MAF bZIP transcription factor K | ENCODES a protein that exhibits RING-like zinc finger domain binding; transcription cis-regulatory region binding; transcription coregulator binding; INVOLVED IN nervous system development; negative regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcriptio n (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 12 | 19948473 | 19970351 | Rat | 180 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 730843 | Mafk | Maf bZIP transcription factor K | Enables DNA-binding transcription factor activity and transcription cis-regulatory region binding activity. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourin ary system; and immune system. Orthologous to human MAFK (MAF bZIP transcription factor K). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 139777291 | 139788409 | Mouse | 206 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1350091 | MAFK | MAF bZIP transcription factor K | The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are als o present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008] | 7 | 1530702 | 1543043 | Human | 194 | symbol , old_gene_name , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8778530 | Mafk | MAF bZIP transcription factor K | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); nervous system developm ent (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | NW_004955460 | 9155713 | 9167291 | Chinchilla | 23 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11763099 | MAFK | MAF bZIP transcription factor K | ENCODES a protein that exhibits RING-like zinc finger domain binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN nervous system development (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway ; FOUND IN nucleoplasm (inferred); nucleus (inferred) | 7 | 1778862 | 1791163 | Bonobo | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12274744 | MAFK | MAF bZIP transcription factor K | ENCODES a protein that exhibits RING-like zinc finger domain binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN nervous system development (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway ; FOUND IN nucleoplasm (inferred); nucleus (inferred) | 6 | 15421918 | 15426650 | Dog | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12540157 | Mafk | MAF bZIP transcription factor K | ENCODES a protein that exhibits RING-like zinc finger domain binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN nervous system development (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway ; FOUND IN nucleoplasm (inferred); nucleus (inferred) | NW_004936754 | 1652412 | 1656570 | Squirrel | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155248413 | mafk | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18452811 | MAFK | MAF bZIP transcription factor K | ENCODES a protein that exhibits RING-like zinc finger domain binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN nervous system development (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway ; FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18926580 | Mafk | MAF bZIP transcription factor K | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RING-like zinc finger domain binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); nervous sy stem development (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13894899 | MAFK | MAF bZIP transcription factor K | ENCODES a protein that exhibits RING-like zinc finger domain binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN nervous system development (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway ; FOUND IN nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 32 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626036074 | Mafk | MAF bZIP transcription factor K | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); nervous system developm ent (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; FOUND IN nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 23 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155248216 | mafk.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155240150 | mafk.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1315457 | BACH1 | BACH transcriptional regulator 1 | This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These B TB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009] | 21 | 29298922 | 29361894 | Human | 244 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1352039 | MAFG | MAF bZIP transcription factor G | Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010] | 17 | 81918270 | 81931244 | Human | 235 | description | gene, protein-coding, VALIDATED [RefSeq] |