| 1305998 | Klk8 | kallikrein related-peptidase 8 | ENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN keratinocyte proliferation (ortholog); memory (ortholog); neuron projection morphogenesis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); serine protea se inhibitor complex (ortholog); INTERACTS WITH acrylamide; ammonium chloride; benzo[a]pyrene | 1 | 103388352 | 103395195 | Rat | 128 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314360 | KLK8 | kallikrein related peptidase 8 | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members l ocated in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] | 19 | 50996008 | 51001604 | Human | 121 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1314361 | Klk8 | kallikrein related-peptidase 8 | This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic clea vage of the activation peptide to generate the functional enzyme. Mice lacking the encoded protein exhibit impaired long-term potentiation and increased anxiety, as well as a hyperkeratosis phenotype. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, May 2016] | 7 | 43447001 | 43453250 | Mouse | 132 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8786163 | Klk8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN keratinocyte proliferation (ortholog); memory (ortholog); neuron projection morphogenesis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); serine protea se inhibitor complex (ortholog) | NW_004955558 | 1479383 | 1484209 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11709133 | KLK8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN synapse organization (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred) | 19 | 47963060 | 47969065 | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12213409 | KLK8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN keratinocyte proliferation (ortholog); memory (ortholog); neuron projection morphogenesis (ortholog); FOUND IN extracellular space (ortholog); seri ne protease inhibitor complex (ortholog) | 1 | 105874788 | 105880788 | Dog | 29 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12547889 | Klk8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN keratinocyte proliferation (ortholog); regulation of synapse organization (ortholog); response to wounding (ortholog); FOUND IN cytoplasm (ortholog ); extracellular space (ortholog); serine protease inhibitor complex (ortholog) | NW_004936889 | 649306 | 653549 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921552 | Klk8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN keratinocyte proliferation (ortholog); regulation of synapse organization (ortholog); response to wounding (ortholog); FOUND IN extracellular space (ortholog); serine protease inhibitor complex (ortholog) | | | | Naked Mole-Rat | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625851348 | Klk8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits peptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN keratinocyte proliferation (ortholog); memory (ortholog); neuron projection morphogenesis (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); serine protea se inhibitor complex (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14127866 | KLK8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN synapse organization (ortholog); FOUND IN cytoplasm (inferred); extracellular space (inferred); serine protease inhibitor complex (inferred) | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18350655 | KLK8 | kallikrein related peptidase 8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN synapse organization (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred) | | | | Green Monkey | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1615981 | Klk1b8 | kallikrein 1-related peptidase b8 | This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic clea vage of the activation peptide to generate the functional enzyme. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, Feb 2016] | 7 | 43600090 | 43604368 | Mouse | 29 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1305359 | Klk1c8 | kallikrein 1-related peptidase C8 | ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); INTERACTS WITH acrylamide; benomyl; bisphenol A | 1 | 103684293 | 103688155 | Rat | 18 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1317964 | KLK9 | kallikrein related peptidase 9 | The protein encoded by this gene is a kallikrein-related serine protease. This gene is activated by steroid hormones in a human breast cancer cell line, making it a good marker for cancer detection. The encoded protein is found primarily in the cytoplasm.[provided by RefSeq, Oct 2010] | 19 | 51002508 | 51009592 | Human | 37 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 16564865 | AC011483.1 | novel transcript, antisense to KLK6, KLK7, KLK8 and KLK9 | | | | | Human | | name | gene, lncrna |
