| 2961 | Kcnmb1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity; calcium-activated potassium channel activity (ortholog); INVOLVED IN cellular response to bile acid; cellular response to ethanol; cellular response to hypoxia; ASSOCIATED WITH increased systemic arterial blood pressure; ASSOCIATE D WITH Experimental Diabetes Mellitus; hypertension; Insulin Resistance; FOUND IN membrane; neuronal cell body; somatodendritic compartment; INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; acrylamide; ammonium chloride | 10 | 19062014 | 19119005 | Rat | 88 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733456 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta su bunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008] | 5 | 170374671 | 170389367 | Human | 88 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 736975 | Kcnmb1 | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | Enables calcium-activated potassium channel activity. Predicted to be involved in several processes, including cellular response to bile acid; cellular response to ethanol; and detection of calcium ion. Located in membrane. Part of voltage-gated potassium channel complex. Is expressed in arterial sy stem; sensory organ; skeleton; and tarsus. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 33912955 | 33923641 | Mouse | 101 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8769122 | Kcnmb1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits calcium-activated potassium channel activity (ortholog); potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Diabetes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | NW_004955408 | 23306286 | 23335170 | Chinchilla | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11930029 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Dia betes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | 5 | 165712588 | 165747948 | Bonobo | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12408960 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Dia betes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | 4 | 41536841 | 41545523 | Dog | 37 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12601600 | Kcnmb1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Dia betes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | NW_004936609 | 4451526 | 4458665 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626102373 | Kcnmb1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits calcium-activated potassium channel activity (ortholog); potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Diabetes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18539665 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Dia betes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | | | | Green Monkey | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285192114 | kcnmb1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18916166 | Kcnmb1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Dia betes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | | | | Naked Mole-Rat | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14146892 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN cellular response to bile acid (ortholog); cellular response to ethanol (ortholog); cellular response to hypoxia (ortholog); ASSOCIATED WITH Diastolic Hypertension, Resistance to (ortholog); Experimental Dia betes Mellitus (ortholog); hypertension (ortholog); FOUND IN membrane (ortholog); neuronal cell body (ortholog); somatodendritic compartment (ortholog) | | | | Pig | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285191433 | kcnmb1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286791925 | kcnmb1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6893415 | Kcnmb1em1Mcwi | potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting allele is a net 4-bp deletion in exon 2 (del 441-447, ins. Tct) | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 6893420 | Kcnmb1em3Mcwi | potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 3, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting allele is a 21-bp deletion in exon 2 and intron 2 (del 18906672-18906692) | | | | Rat | | symbol , old_gene_symbol | gene, allele |