| 1307688 | Isy1 | ISY1 spliceosome associated protein | ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog ); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 121833870 | 121854561 | Rat | 81 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317021 | Isy1 | ISY1 splicing factor homolog | Predicted to be involved in generation of catalytic spliceosome for second transesterification step and mRNA 3'-splice site recognition. Predicted to be located in nucleus. Predicted to be part of Prp19 complex and spliceosomal complex. Is expressed in cerebral cortex intermediate zone; cerebral cor tex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to several human genes including ISY1 (ISY1 splicing factor homolog). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 87795429 | 87815723 | Mouse | 87 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606526 | ISY1 | ISY1 spliceosome associated protein | Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type catalytic step 1 spliceosome and catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 129127415 | 129161063 | Human | 77 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8751071 | Isy1 | ISY1 spliceosome associated protein | INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog) | NW_004955429 | 13513191 | 13527516 | Chinchilla | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11990079 | ISY1 | ISY1 spliceosome associated protein | INVOLVED IN generation of catalytic spliceosome for second transesterification step (inferred); mRNA splicing, via spliceosome (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | 3 | 126187354 | 126219355 | Bonobo | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12267637 | ISY1 | ISY1 spliceosome associated protein | INVOLVED IN generation of catalytic spliceosome for second transesterification step (inferred); mRNA splicing, via spliceosome (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | 20 | 2945636 | 2972245 | Dog | 20 | symbol , old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 18517110 | ISY1 | ISY1 spliceosome associated protein | INVOLVED IN generation of catalytic spliceosome for second transesterification step (inferred); mRNA splicing, via spliceosome (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Green Monkey | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14377657 | ISY1 | | | | | | Yeast | | symbol | gene, null |
| 155257963 | isy1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18912106 | Isy1 | ISY1 spliceosome associated protein | INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); U2-type catalytic step 1 spliceosome (ortholog) | | | | Naked Mole-Rat | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155249648 | isy1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 5507896 | ISY1-RAB43 | ISY1-RAB43 readthrough | This locus represents naturally occurring read-through transcription between the neighboring ISY1 (ISY1 splicing factor homolog) and RAB43 (RAB43, member RAS oncogene family) gene on chromosome 3. The read-through transcript encodes a protein that shares sequence identity with the upstream gene product, but its C-terminus is distinct due to a frameshift relative to the downstream gene. [provided by RefSeq, Mar 2011] | 3 | 129087572 | 129161063 | Human | 28 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12618334 | LOC101962734 | pre-mRNA-splicing factor ISY1 homolog | INVOLVED IN generation of catalytic spliceosome for second transesterification step (inferred); mRNA splicing, via spliceosome (inferred); FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | NW_004936798 | 192308 | 202367 | Squirrel | 8 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14139623 | LOC102162880 | pre-mRNA-splicing factor ISY1 homolog | INVOLVED IN generation of catalytic spliceosome for second transesterification step (inferred); mRNA splicing, via spliceosome (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN catalytic step 2 spliceosome (inferred); nuclear speck (inferred); nucleus (inferred) | | | | Pig | 20 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1603859 | RAB43 | RAB43, member RAS oncogene family | Enables GTPase activity. Involved in Golgi organization; phagosome maturation; and retrograde transport, plasma membrane to Golgi. Located in Golgi apparatus and phagocytic vesicle. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 129087569 | 129122150 | Human | 105 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 625999517 | LOC116903535 | pre-mRNA-splicing factor ISY1 homolog | | | | | Black Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 18899654 | LOC106008967 | pre-mRNA-splicing factor ISY1 homolog pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |