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53 records found for search term Il22
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1344987IL22interleukin 22This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several in126824824268253604Human136symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1556865Il22interleukin 22Enables cytokine activity. Involved in negative regulation of inflammatory response. Acts upstream of or within reactive oxygen species metabolic process and regulation of macromolecule metabolic process. Is active in extracellular space. Is expressed in ileum; retina; and skin. Used to study liposa10118040456118045952Mouse86symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1561292Il22interleukin 22ENCODES a protein that exhibits cytokine activity (ortholog); INVOLVED IN response to glucocorticoid; negative regulation of inflammatory response (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling75568706155691526Rat73symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
8876132Il22interleukin 22INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN decoy receptor complex (ortholog); extracellular space (ortholog); receptor complex (ortholog)NW_0049554581474733914755602Chinchilla21symbolgene, protein-coding, MODEL [RefSeq]
11883625IL22interleukin 22ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN extracellular space (ortholog)126575706965762418Bonobo25symbolgene, protein-coding, MODEL [RefSeq]
12222915IL22interleukin 22ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN extracellular space (ortholog)101048736710492238Dog28symbolgene, protein-coding, MODEL [RefSeq]
12520790Il22interleukin 22ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN extracellular space (ortholog)NW_00493654562271186231745Squirrel24symbolgene, protein-coding, MODEL [RefSeq]
14145806IL22interleukin 22ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH deoxynivalenol; NivalenolPig31symbolgene, protein-coding, MODEL [RefSeq]
18775517IL22interleukin 22ENCODES a protein that exhibits cytokine activity (inferred); INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN extracellular space (ortholog)Green Monkey25symbolgene, protein-coding, MODEL [RefSeq]
18925936Il22interleukin 22INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN extracellular space (ortholog)Naked Mole-Rat20symbolgene, protein-coding, MODEL [RefSeq]
155256414il22Tropical Clawed Frogsymbolgene, null
625869546Il22interleukin 22INVOLVED IN response to glucocorticoid (ortholog); ASSOCIATED WITH Acute Otitis Media (ortholog); asthma (ortholog); autoimmune hepatitis (ortholog); FOUND IN decoy receptor complex (ortholog); extracellular space (ortholog); receptor complex (ortholog)Black Rat21symbolgene, protein-coding, MODEL [RefSeq]
1614980Il22binterleukin 22BPredicted to enable cytokine activity. Predicted to be involved in negative regulation of inflammatory response. Predicted to be active in extracellular space. Is expressed in retina. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL2210118125534118130943Mouse113symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1352751IL22RA1interleukin 22 receptor subunit alpha 1The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleuk12411977124143140Human98symbol , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1557122Il22ra1interleukin 22 receptor, alpha 1Enables interleukin-20 binding activity and interleukin-22 receptor activity. Involved in negative regulation of inflammatory response. Acts upstream of or within defense response to Gram-negative bacterium and negative regulation of cytokine production involved in inflammatory response. Predicted t4135455470135482694Mouse100symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1559655Il22ra1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits interleukin-20 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of inflammatory response (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat s5153245067153269865Rat92symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
8901070Il22ra1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits interleukin-20 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN interleukinNW_00495545239755973992809Chinchilla10symbolgene, protein-coding, MODEL [RefSeq]
11684470IL22RA1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN plasma membrane (inferred)12332205723345557Bonobo14symbolgene, protein-coding, MODEL [RefSeq]
12172398IL22RA1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN plasma membrane (inferred)27545408775475211Dog15symbolgene, protein-coding, MODEL [RefSeq]
12640998Il22ra1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN plasma membrane (inferred)NW_00493647491845599201918Squirrel14symbolgene, protein-coding, MODEL [RefSeq]
13989957IL22RA1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN plasma membrane (inferred); IPig18symbolgene, protein-coding, MODEL [RefSeq]
18714201IL22RA1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-20 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN plasma membrane (inferred)Green Monkey12symbolgene, protein-coding, MODEL [RefSeq]
18936475Il22ra1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits interleukin-20 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN interleukinNaked Mole-Rat15symbolgene, protein-coding, MODEL [RefSeq]
405855884il22ra1Tropical Clawed Frogsymbolgene, null
405857253il22ra1Tropical Clawed Frogsymbolgene, null
405862860il22ra1Tropical Clawed Frogsymbolgene, null
405863049il22ra1Tropical Clawed Frogsymbolgene, null
598150866il22ra1Tropical Clawed Frogsymbolgene, null
598151006il22ra1Tropical Clawed Frogsymbolgene, null
598153050il22ra1Tropical Clawed Frogsymbolgene, null
598154450il22ra1Tropical Clawed Frogsymbolgene, null
626100617Il22ra1interleukin 22 receptor subunit alpha 1ENCODES a protein that exhibits interleukin-20 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN defense response to Gram-negative bacterium (ortholog); negative regulation of inflammatory response (ortholog); ASSOCIATED WITH Rhinosinusitis (ortholog); FOUND IN interleukinBlack Rat10symbolgene, protein-coding, MODEL [RefSeq]
1303169Il22ra2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits interleukin-22 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); PARTICIPATES IN cytokine mediated signaling pathway;11617223816228009Rat63symbol , PhenoGen , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1322028IL22RA2interleukin 22 receptor subunit alpha 2This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflamma6137143820137173644Human61symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1322029Il22ra2interleukin 22 receptor, alpha 2Predicted to enable interleukin-22 binding activity and interleukin-22 receptor activity. Acts upstream of or within negative regulation of inflammatory response and regulation of tyrosine phosphorylation of STAT protein. Located in cytosol. Orthologous to human IL22101949777619510429Mouse66symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
8702540Il22ra2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits interleukin-22 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH multisystem inflammatory syndrome inNW_0049554362220826722219667Chinchilla10symbolgene, protein-coding, MODEL [RefSeq]
12011296IL22RA2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-22 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WI6134904634134934328Bonobo14symbolgene, protein-coding, MODEL [RefSeq]
12289387IL22RA2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits interleukin-22 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH multisystem inflammatory syndrome in12961109629631811Dog14symbolgene, protein-coding, MODEL [RefSeq]
12461370Il22ra2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-22 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WINW_00493656044932794506973Squirrel14symbolgene, protein-coding, MODEL [RefSeq]
13923141IL22RA2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits interleukin-22 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH multisystem inflammatory syndrome inPig15symbolgene, protein-coding, MODEL [RefSeq]
18668483IL22RA2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits cytokine receptor activity (inferred); interleukin-22 binding (inferred); interleukin-22 receptor activity (inferred); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WIGreen Monkey14symbolgene, protein-coding, MODEL [RefSeq]
18913448Il22ra2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits interleukin-22 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH multisystem inflammatory syndrome inNaked Mole-Rat14symbolgene, protein-coding, MODEL [RefSeq]
626079104Il22ra2interleukin 22 receptor subunit alpha 2ENCODES a protein that exhibits interleukin-22 binding (ortholog); interleukin-22 receptor activity (ortholog); INVOLVED IN negative regulation of inflammatory response (ortholog); regulation of tyrosine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH multisystem inflammatory syndrome inBlack Rat10symbolgene, protein-coding, MODEL [RefSeq]
405855885il22ra1.LAfrican Clawed Frogsymbolgene, null
405857252il22ra1.LAfrican Clawed Frogsymbolgene, null
405857511il22ra1.LAfrican Clawed Frogsymbolgene, null
405863922il22ra1.LAfrican Clawed Frogsymbolgene, null
626188358il22ra1.LAfrican Clawed Frogsymbolgene, null
405856232il22ra1.SAfrican Clawed Frogsymbolgene, null
405862861il22ra1.SAfrican Clawed Frogsymbolgene, null
405863048il22ra1.SAfrican Clawed Frogsymbolgene, null
405865048il22ra1.SAfrican Clawed Frogsymbolgene, null
626468746il22ra1.SAfrican Clawed Frogsymbolgene, null