| 1306512 | Igf2bp3 | insulin-like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA 5'-UTR binding (ortholog); N6-methyladenosine-containing RNA reader activity (ortholog); INVOLVED IN CRD-mediated mRNA stabilization (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ort holog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol | 4 | 79391367 | 79525923 | Rat | 169 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1332348 | Igf2bp3 | insulin-like growth factor 2 mRNA binding protein 3 | Predicted to enable N6-methyladenosine-containing RNA reader activity; mRNA 3'-UTR binding activity; and mRNA 5'-UTR binding activity. Predicted to be involved in CRD-mediated mRNA stabilization and nervous system development. Predicted to be located in P-body and cytoplasmic stress granule. Predict ed to be active in cytosol and nucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; liver; and sensory organ. Orthologous to human IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 49062152 | 49200225 | Mouse | 174 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606570 | IGF2BP3 | insulin like growth factor 2 mRNA binding protein 3 | The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are im portant in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008] | 7 | 23310209 | 23470491 | Human | 177 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8809888 | Igf2bp3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA 5'-UTR binding (ortholog); N6-methyladenosine-containing RNA reader activity (ortholog); INVOLVED IN CRD-mediated mRNA stabilization (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ort holog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog) | NW_004955410 | 25605323 | 25734845 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11730240 | IGF2BP3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); regulation of cytokine production (inferred); ASSOCIATED WI TH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred) | 7 | 23994839 | 24148709 | Bonobo | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12192624 | IGF2BP3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); regulation of translation (inferred); ASSOCIATED WITH Exper imental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred) | 14 | 36969128 | 37120609 | Dog | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12635688 | Igf2bp3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); regulation of translation (inferred); ASSOCIATED WITH Exper imental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred) | NW_004936478 | 456369 | 595705 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18514782 | IGF2BP3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); regulation of cytokine production (inferred); ASSOCIATED WI TH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257824 | igf2bp3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18925526 | Igf2bp3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); regulation of translation (inferred); ASSOCIATED WITH Exper imental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred) | | | | Naked Mole-Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14242047 | IGF2BP3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); regulation of translation (inferred); ASSOCIATED WITH Exper imental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred) | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626148989 | Igf2bp3 | insulin like growth factor 2 mRNA binding protein 3 | ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); mRNA 5'-UTR binding (ortholog); N6-methyladenosine-containing RNA reader activity (ortholog); INVOLVED IN CRD-mediated mRNA stabilization (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ort holog); malignant mesothelioma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246104 | igf2bp3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155260111 | igf2bp3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38637714 | IGF2BP3P1 | IGF2BP3 pseudogene 1 | | 6 | 166699361 | 166703092 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38660489 | IGF2BP3P2 | IGF2BP3 pseudogene 2 | | 7 | 56597548 | 56601545 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16551962 | AC092447.1 | insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) pseudogene | | | | | Human | | name | gene, processed_pseudogene |