IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3) - Rat Genome Database

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Gene: IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3) Pan paniscus
Analyze
Symbol: IGF2BP3
Name: insulin like growth factor 2 mRNA binding protein 3
RGD ID: 11730240
Description: ENCODES a protein that exhibits mRNA 3'-UTR binding (inferred); mRNA 5'-UTR binding (inferred); N6-methyladenosine-containing RNA reader activity (inferred); INVOLVED IN CRD-mediated mRNA stabilization (inferred); mRNA transport (inferred); nervous system development (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: insulin-like growth factor 2 mRNA-binding protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2628,176,554 - 28,330,030 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1776,501,280 - 76,654,760 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0723,994,839 - 24,148,709 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1723,602,905 - 23,755,414 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl723,602,905 - 23,755,473 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IGF2BP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2628,176,554 - 28,330,030 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1776,501,280 - 76,654,760 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0723,994,839 - 24,148,709 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1723,602,905 - 23,755,414 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl723,602,905 - 23,755,473 (-)Ensemblpanpan1.1panPan2
IGF2BP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38723,310,209 - 23,470,491 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl723,310,209 - 23,470,491 (-)EnsemblGRCh38hg38GRCh38
GRCh37723,349,828 - 23,510,110 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36723,316,353 - 23,476,520 (-)NCBINCBI36Build 36hg18NCBI36
Celera723,336,115 - 23,496,228 (-)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef723,232,126 - 23,392,057 (-)NCBIHuRef
CHM1_1723,350,413 - 23,510,906 (-)NCBICHM1_1
T2T-CHM13v2.0723,446,649 - 23,606,903 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2723,401,705 - 23,561,835 (-)NCBI
Igf2bp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39649,062,152 - 49,200,225 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl649,062,157 - 49,191,891 (-)EnsemblGRCm39 Ensembl
GRCm38649,085,218 - 49,215,469 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl649,085,223 - 49,214,957 (-)EnsemblGRCm38mm10GRCm38
MGSCv37649,035,217 - 49,164,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36649,014,807 - 49,144,299 (-)NCBIMGSCv36mm8
Celera649,595,319 - 49,724,863 (-)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map623.82NCBI
Igf2bp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8479,391,367 - 79,525,923 (-)NCBIGRCr8
mRatBN7.2478,060,494 - 78,195,007 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl478,060,494 - 78,194,865 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx483,269,661 - 83,402,360 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0479,045,139 - 79,177,835 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0477,485,441 - 77,618,137 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0478,744,683 - 78,879,457 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,746,547 - 78,879,294 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04143,433,379 - 143,568,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4477,213,559 - 77,228,004 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1477,487,753 - 77,623,158 (-)NCBI
Celera472,996,368 - 73,130,584 (-)NCBICelera
Cytogenetic Map4q24NCBI
Igf2bp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541025,605,323 - 25,731,169 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541025,605,323 - 25,734,845 (-)NCBIChiLan1.0ChiLan1.0
IGF2BP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11436,969,128 - 37,120,609 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1436,971,420 - 37,120,193 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1436,509,804 - 36,661,057 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01436,899,592 - 37,050,855 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1436,901,884 - 37,051,361 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11437,014,655 - 37,165,902 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01436,710,919 - 36,862,045 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01437,048,010 - 37,199,653 (-)NCBIUU_Cfam_GSD_1.0
Igf2bp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511881,245,124 - 81,384,026 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936478458,871 - 595,742 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936478456,369 - 595,705 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGF2BP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl992,104,848 - 92,272,211 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1992,104,786 - 92,272,264 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29101,678,002 - 101,811,092 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IGF2BP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12134,846,383 - 34,999,579 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2134,954,129 - 34,997,439 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604269,607,584 - 69,762,351 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igf2bp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247397,158,020 - 7,319,720 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247397,154,893 - 7,319,724 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000043970   ⟹   ENSPPAP00000021170
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl723,602,905 - 23,755,473 (-)Ensembl
RefSeq Acc Id: XM_003807939   ⟹   XP_003807987
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2628,176,554 - 28,330,030 (-)NCBI
NHGRI_mPanPan1776,501,280 - 76,654,760 (-)NCBI
Mhudiblu_PPA_v0723,994,839 - 24,148,708 (-)NCBI
PanPan1.1723,602,905 - 23,755,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008960055   ⟹   XP_008958303
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2628,176,554 - 28,329,987 (-)NCBI
NHGRI_mPanPan1776,501,280 - 76,654,712 (-)NCBI
Mhudiblu_PPA_v0723,994,839 - 24,148,708 (-)NCBI
PanPan1.1723,602,905 - 23,755,413 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034963801   ⟹   XP_034819692
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2628,176,554 - 28,329,987 (-)NCBI
NHGRI_mPanPan1776,501,280 - 76,654,712 (-)NCBI
Mhudiblu_PPA_v0723,994,839 - 24,148,709 (-)NCBI
RefSeq Acc Id: XM_055115773   ⟹   XP_054971748
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2628,176,554 - 28,329,133 (-)NCBI
NHGRI_mPanPan1776,501,280 - 76,653,859 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003807987 (Get FASTA)   NCBI Sequence Viewer  
  XP_008958303 (Get FASTA)   NCBI Sequence Viewer  
  XP_034819692 (Get FASTA)   NCBI Sequence Viewer  
  XP_054971748 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000021170
  ENSPPAP00000021170.1
Reference Protein Sequences
RefSeq Acc Id: XP_003807987   ⟸   XM_003807939
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AZ93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958303   ⟸   XM_008960055
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034819692   ⟸   XM_034963801
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000021170   ⟸   ENSPPAT00000043970
RefSeq Acc Id: XP_054971748   ⟸   XM_055115773
- Peptide Label: isoform X1
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033809 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000043970.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
  3.30.310.210 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
KEGG Report pps:100992581 UniProtKB/TrEMBL
NCBI Gene IGF2BP3 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3 UniProtKB/TrEMBL
  KH DOMAIN CONTAINING RNA BINDING PROTEIN UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
  SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A2R9AZ93 ENTREZGENE, UniProtKB/TrEMBL