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Gene: IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3) Homo sapiens
Symbol: IGF2BP3
Name: insulin like growth factor 2 mRNA binding protein 3
Description: Exhibits mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in negative regulation of translation. Localizes to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 98; CT98; DKFZp686F1078; hKOC; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; IGF2 mRNA-binding protein 3; IMP-3; IMP3; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC; KOC1; VICKZ family member 3; VICKZ3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: IMP3 (Gene ID: 55272) and IGF2BP3 (Gene ID: 10643) share the IMP3 symbol/alias in common. IMP3 is a widely used alternative name for insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), which can be confused with the official symbol for IMP3, U3 small nucleolar ribonucleoprotein (IMP3). [17 May 2018]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl723,310,209 - 23,470,491 (-)Ensembl
GRCh38723,310,209 - 23,470,674 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37723,349,828 - 23,509,995 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36723,316,353 - 23,476,520 (-)NCBINCBI36hg18NCBI36
Celera723,336,115 - 23,496,228 (-)NCBI
Cytogenetic Map7p15.3NCBI
HuRef723,232,126 - 23,392,057 (-)NCBIHuRef
CHM1_1723,350,413 - 23,510,906 (-)NCBICHM1_1
CRA_TCAGchr7v2723,401,705 - 23,561,835 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IGF2BP3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606570
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.