| 1354432 | HOXD9 | homeobox D9 | This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on diff erent chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008] | 2 | 176122719 | 176124937 | Human | 88 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1582908 | Hoxd9 | homeo box D9 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); em bryonic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate | 3 | 80008006 | 80010186 | Rat | 92 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1615190 | Hoxd9 | homeobox D9 | Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within several processes, including limb morphogenesis; peripheral nervous system neuron development; and regionalization. Located in nucleus. Is expressed in several structures, including embryo mesenchy me; genitourinary system; gut; integumental system; and limb. Orthologous to human HOXD9 (homeobox D9). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 74528107 | 74530552 | Mouse | 144 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 10360993 | Hoxd9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); em bryonic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955451 | 12619722 | 12621320 | Chinchilla | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11977058 | HOXD9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); embry onic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | 2B | 63401813 | 63404731 | Bonobo | 55 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12125836 | HOXD9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); embry onic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | 36 | 19929479 | 19932861 | Dog | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12614925 | Hoxd9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); embry onic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936509 | 5609744 | 5611943 | Squirrel | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14136910 | HOXD9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); embry onic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925671 | Hoxd9 | homeobox D9 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN adult locomotory beha vior (ortholog); anterior/posterior pattern specification (ortholog); embryonic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625972112 | Hoxd9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); em bryonic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18497054 | HOXD9 | homeobox D9 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN adult locomotory behavior (ortholog); anterior/posterior pattern specification (ortholog); embry onic forelimb morphogenesis (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); hepatocellular carcinoma (ortholog); mucinous adenocarcinoma (ortholog); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239665 | hoxd9 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 39131491 | HOXD9 | homeobox D9 | | | | | Chinchilla | | symbol | gene, protein-coding |
| 155250521 | hoxd9.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239664 | hoxd9.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 8931447 | LOC102005213 | homeobox protein Hox-B6 | | NW_004955403 | 20538174 | 20539079 | Chinchilla | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1348415 | EVX2 | even-skipped homeobox 2 | This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5 ' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009] | 2 | 176077472 | 176083962 | Human | 35 | description | gene, protein-coding, REVIEWED [RefSeq] |