| 2682 | Ggh | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity; INVOLVED IN response to ethanol; response to insulin; response to xenobiotic stimulus; PARTICIPATES IN folate metabolic pathway; hereditary folate malabsorption pathway; methotrexate pharmacodynamics pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space; endoplasmic reticulum (ortholog); INTERACTS WITH 3H-1,2-dithiole-3-thione; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil | 5 | 38326747 | 38349655 | Rat | 154 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10636 | Ggh | gamma-glutamyl hydrolase | Predicted to enable gamma-glutamyl-peptidase activity. Predicted to be involved in several processes, including response to ethanol; response to insulin; and tetrahydrofolylpolyglutamate metabolic process. Located in extracellular space. Orthologous to human GGH (gamma-glutamyl hydrolase). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 20041963 | 20066111 | Mouse | 167 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 735324 | GGH | gamma-glutamyl hydrolase | This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008] | 8 | 63015079 | 63038806 | Human | 163 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9032028 | Ggh | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog) | NW_004955444 | 15901225 | 15930358 | Chinchilla | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11734110 | GGH | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space (ortholog) | 8 | 59547821 | 59571523 | Bonobo | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12409633 | GGH | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space (ortholog) | 29 | 13143881 | 13165028 | Dog | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12652354 | Ggh | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space (ortholog) | NW_004936496 | 10485528 | 10505506 | Squirrel | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18614983 | GGH | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space (ortholog) | | | | Green Monkey | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625932771 | Ggh | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog) | | | | Black Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919543 | Ggh | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog) | | | | Naked Mole-Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14060811 | GGH | gamma-glutamyl hydrolase | ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorpt ion pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space (ortholog) | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250808 | ggh | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155236709 | ggh.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 13993485 | TTPA | alpha tocopherol transfer protein | ENCODES a protein that exhibits phosphatidylinositol-3,4-bisphosphate binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); vitamin binding (ortholog); INVOLVED IN embryonic placenta development (ortholog); intracellular pH reduction (ortholog); negative regulation of epithel ial cell apoptotic process (ortholog); ASSOCIATED WITH Abnormal Reflexes (ortholog); Animal Disease Models (ortholog); Ataxia (ortholog); FOUND IN late endosome (ortholog) | | | | Pig | 58 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |