Ggh (gamma-glutamyl hydrolase) - Rat Genome Database

Name: Ggh
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Ggh (gamma-glutamyl hydrolase) Ictidomys tridecemlineatus

Analyze

Symbol:

Ggh

Name:

gamma-glutamyl hydrolase

RGD ID:

12652354

Description:

ENCODES a protein that exhibits gamma-glutamyl-peptidase activity (ortholog); INVOLVED IN response to ethanol (ortholog); response to insulin (ortholog); response to xenobiotic stimulus (ortholog); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorption pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GGH (gamma-glutamyl hydrolase)	NCBI	Ortholog
Mus musculus (house mouse):	Ggh (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ggh (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ggh (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GGH (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GGH (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GGH (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GGH (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ggh (gamma-glutamyl hydrolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	64,282,077 - 64,299,958 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	10,485,504 - 10,505,842 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	10,485,528 - 10,505,506 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

Colorectal Neoplasms (ISO)

COVID-19 (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

rheumatoid arthritis (ISO)

transitional cell carcinoma (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glutamine metabolic process (IEA)

response to ethanol (ISO)

response to insulin (ISO)

response to xenobiotic stimulus (ISO)

response to zinc ion (ISO)

tetrahydrofolylpolyglutamate metabolic process (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA,ISO)

vacuole (IEA)

Molecular Function

gamma-glutamyl-peptidase activity (IEA,ISO)

hydrolase activity (IEA)

omega peptidase activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

folate cycle metabolic pathway (ISO)

folate metabolic pathway (ISO)

hereditary folate malabsorption pathway (ISO)

methotrexate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Ggh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	64,282,077 - 64,299,958 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936496	10,485,504 - 10,505,842 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936496	10,485,528 - 10,505,506 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GGH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	63,015,079 - 63,038,806 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	63,014,881 - 63,039,407 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	63,927,638 - 63,951,365 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	64,090,192 - 64,113,940 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	64,090,194 - 64,113,940	NCBI
Celera	8	59,917,838 - 59,941,813 (-)	NCBI		Celera
Cytogenetic Map	8	q12.3	NCBI
HuRef	8	59,415,504 - 59,439,479 (-)	NCBI		HuRef
CHM1_1	8	63,980,633 - 64,004,623 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	63,439,652 - 63,463,378 (-)	NCBI		T2T-CHM13v2.0

Ggh
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	20,041,963 - 20,066,111 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	20,042,052 - 20,066,750 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	20,041,997 - 20,066,111 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	20,042,052 - 20,066,750 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	19,969,199 - 19,993,258 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	20,164,971 - 20,188,858 (+)	NCBI		MGSCv36	mm8
Celera	4	19,800,007 - 19,824,562 (+)	NCBI		Celera
Cytogenetic Map	4	A3	NCBI
cM Map	4	7.79	NCBI

Ggh
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	38,326,747 - 38,349,655 (+)	NCBI		GRCr8
mRatBN7.2	5	33,529,880 - 33,552,790 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	33,529,880 - 33,552,787 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	35,643,220 - 35,666,193 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	37,235,432 - 37,258,403 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	37,174,941 - 37,197,912 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	34,040,258 - 34,063,369 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	34,040,258 - 34,063,361 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	38,693,591 - 38,716,702 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	34,670,883 - 34,693,791 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	34,671,061 - 34,693,969 (+)	NCBI
Celera	5	32,605,342 - 32,628,233 (+)	NCBI		Celera
Cytogenetic Map	5	q13	NCBI

Ggh
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955444	15,900,485 - 15,931,338 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955444	15,901,225 - 15,930,358 (+)	NCBI	ChiLan1.0	ChiLan1.0

GGH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	78,741,363 - 78,769,505 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	54,380,324 - 54,408,566 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	59,547,821 - 59,571,523 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	61,222,194 - 61,246,096 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	61,222,194 - 61,246,252 (-)	Ensembl	panpan1.1		panPan2

GGH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	13,143,881 - 13,165,028 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	13,134,232 - 13,165,028 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	13,471,573 - 13,492,163 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	13,246,558 - 13,267,739 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	13,245,957 - 13,267,728 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	13,258,091 - 13,279,415 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	13,375,202 - 13,396,822 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	13,641,119 - 13,662,465 (-)	NCBI		UU_Cfam_GSD_1.0

GGH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	70,996,755 - 71,021,838 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	70,996,730 - 71,020,513 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	77,279,213 - 77,303,313 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GGH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	58,908,524 - 58,932,885 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	58,908,417 - 58,932,685 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	82,649,447 - 82,674,608 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ggh
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624744	28,752,909 - 28,785,661 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624744	28,752,785 - 28,786,293 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005322970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021724913	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000013288 ⟹ ENSSTOP00000011910

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936496	10,485,504 - 10,505,842 (+)	Ensembl

RefSeq Acc Id:

XM_005322970 ⟹ XP_005323027

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	64,282,077 - 64,299,958 (-)	NCBI
SpeTri2.0	NW_004936496	10,485,528 - 10,505,506 (+)	NCBI

Sequence:

show sequence

GCGAGCCAGGGGCCCTGAGGCCGCCGTGGCCGCCGCGGCGCTAGCCCGCACGGCTGCAGTGCCT
TTGAACTGCGGCGGGAGGCGGCCGGCGTGATGGCTAGTCTGGGTCGCCTGCTGTGCGTGGTGGG
CCTGCTACTCTGCGGGGCAGCCAGCCTGGGGCTGTGCAAATCCCACACAACTGCCGCGAAGAAT
CCCATCATCGGAATATTAATGCAAAAATGCCATAAGGAAATGAAAAACTTTGGAAGATATTATA
TTGCTGCATCCTATGTGAAGTATCTAGAGTCTGCAGGTGCAAGAGTTATACCAATAAGGCTTGA
TCTTACACATGCAGAATATGAAAAACTTTTCAAATCTATCAATGGAATCCTTTTCCCTGGAGGA
AGTGTTGACCTTAAGCGCTCAGATTATGCTCAAGTAGCCAAAATATTTTACGACTTGGCCATAC
AGAGTTATGATGATGGAGACTATTTTCCTGTGTGGGGCACATGCCTTGGATTTGAGGAGCTCAC
TTATCTGGTTAGTGGGGAGTGCTTATTAACTCACACAGAACACACTGTTGCAGTGACATTGCCG
CTGAATTTCACTGGAGCTACATTGCAGAGCAGAATGTTCCAGAATTTTCCTGCTGACTTGTTGC
TGTCATTAGCAACAGAACCCCTGACTGCAAATTTCCACAAATGGAGCCTTTCCATAAAGAATTT
TACGTTGAATGAAAAGTTAAGCAAGTTTTTCAGTGTGTTAACTACGAATAGAGATGACAAGATT
GAGTTCATTTCATCGATGGAAGGATATAAGTATCCAGTATATGGTGTCCAGTGGCATCCAGAGA
AAGCACCTTATGAATGGGAGAAATTACAAGGCATTTCACATGAACCTAATGCTGTGAAGACTGC
ATTTTATTTAGCAGAGTTCTTTGTTTCTGAAGCTCGGAAAAATGATCATCACTTTGAATCTCAA
TCTGAGGAGGAGAAAGCCCTGATTTATCAGTTCCGTCCAATTTATACTGGAAATTTTTCTTCAT
TTCAGCAATGTTATATGTTTGATTGAAAATCTTTGATGTGTTAACAGAGCACTTTGAATAATTC
TGTGATTAAACTATTATAATAACTCATTATTAATGGCAATATTAGAAAGCTACAGAGATTCCCT
TTCTATGTGATTAGCTCTGATTTTTAAATCAATATATGATTTTTTAAATCACCTTTGATAATTC
ATCAGAGACAGATAATCATAGTGTTTTCATGGCAAAGCCTTTATGTCTGAAGATAGAAAAAAAA
TGTATTGAGAATTCAAATTTTTTTTCTGATGTACTGATTTTAGAAATAAATACCACTCCTTACC
CATCCATCCCATTTTTATTGGGAGACTTTCATTTTATATTATTATTTATGGTGTTGGGGATTGA
TCTCAGGGTCTTATACATGCTGAACAAGGGCTCTGCTGCTGAGCTACATTTCAGCATTAAGAAT
TTAAATCCTACCTCTATACCCTGGGATGCCTCCCTCCTTTGGGTCTCAGGATTATGTTGTTGTG
TGAGTGGTATGTGTGCAGAGAAACATAAATATCTCCTTTTGCCTCCATTTTAGTTCCGCAATTA
GAGGGCACACATCCTGCAGACAGTCTGTGCCTTGAACTATTATCTTCTATCATGTCTAGTACAC
AGGCCCTTGATGAACATCTGTGACTACTCGTATTTTCCATATCCATGGAAAATAATTAAAAAGC
TGTCATGCATTGATTTCAGTGCATTTGAATATATTTCTCAATCTGTGCTATACTCTTTTATCCC
TTACCATCCTATATAGACCCTCAAAAGTCTGAAATTTACACATTCCCTAAGGATAAGCAAGCTG
TTAGAAAAAAAAAAGAGGATTTTTTTGACCTGTGTTTAATAAAATGTGTTTATGCATCTCTTCT
TTGTGGTCTTTAGAGCTGCAGCTAGAGAACAAAACCCCAGGAAATTAGTAAAAACATTGGAGGA
CATTATGAATGATATTATTTACAGAAAGATAAGAATAATAATCTGAAGAAACTGAGAGGTAAAT
CACACTCTTTGAACAAAAAGGATGAATGGAATATAGAAATTGAAAGGATTGACAAATTTAGTCA
GCCAAGAAAGAACTTTAATAGAAATCTGGCAGACTTAGTTTTTTTTTTTTTCTTTCTTTTTTTA
TTATGTCTTGCTGTCTAATGTGCCATTTCTGGCAAGGCTCAAGTCTTCTACCACTAGAAAAGGT
AGTGGCACTATTCCCACTCCCCATACCAGGCCTCTTCCTGACCTTTTGTTAGAACCATATAGAT
CTGCTTGTCTCTGCAGAGCCCTAACGGCACTTCACACTGACTGCTCATTCATCACTCATGCTGT
GTCCATCCTGCCCATGAATATTGACTTCTAGTTGTTTCCGGTGGTTCTTACTGGGCTTTATTGA
TGATGCCCACAAATGCAAGAAAATGTAAAAAGATTGTTTCTGCTCATGTTTAATTTACCATTTT
CCATGTACTTTTTTAGAGTCCTCATGCTAGAATCACTTTATTCCCAAAATGGGATTTGTTCCAA
AGTTGTGTATACCTTGCTTTCCATACTCCATCAGCGATAGGTAAGGGTTTGAGGACAAATGAGA
AGAGCAGGCTGTTCAGGTAGAGAAGGTCCCTCAGTGAGCCAGGTACCACTACATCAGTAGGAGC
AAGAAGGACATTGATGAGAAAATTTGCCTGTTAATGCTTTGAGCAGCAGTCTGGAAAACCCTGG
GCCTTACAATGTGGAGGGAGCAGAGGCTGAAGGAAAGAGTGGCTGTAGGAGTGTATATGGATTA
GAAAGAGGAACTACAAGAAAGGAAGGATTGGGTAAGCCTGGGCCTTGTACATAGAAGAGACAGA
AGATGTATTCCCTGCCCCAGCTCACAGCTGATTTCAGTTTCCATGGCTTTTTAGAAAAAAGTTT
TTATCTTCATCATTTCTCATTCTTTTACTTATGTGGAATATCCCAAATAGAAAGAAAATGTTGA
TATTAAGGGCCTTCACTCATTTCTATTCAGCTAGATTGCCCTAAGAACCCACAGTTTAGGCCTG
GCACTATATTTTATGAGGGCATATTAAGTGTCTCCTCATTTCCACAAAGCAAAGTAGGGAAATC
CTCAAAACCTTGTGCATAGGCCAAGATTCCATGGTTTAGAATGGTCCAGCAGTTTCTGAAAGCA
TAGAGATAACTACAGTGGAAGTCTACAAGTCCAGCGCCTGACACACAGTAGGACCTCAGAGAGT
GAGTGCCTTTCCTTCATTTCTCTACCTCTCTGTGATATGGAACGCCTCCGAATGTGCTGGGTCT
CTCTGTTTTTACTCTACAGAATTGTGAGAAAATATACCATTGCAGGGTTTTCCCAGGGGAAGAG
TTAAAAATAAAAGTGCCATTCCTTAGGAACAGAAGCTTTGTTATTATTTTGTTTGGAGCCTTAT
TCCAT

hide sequence

RefSeq Acc Id:

XM_021724913 ⟹ XP_021580588

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	64,282,077 - 64,299,887 (-)	NCBI
SpeTri2.0	NW_004936496	10,485,665 - 10,505,506 (+)	NCBI

Sequence:

show sequence

CTGCGGGGCAGCCAGCCTGGGGCTGTGCAAATCCCACACAACTGCCGCGAAGAATCCCATCATC
GCCAAATTTAATTTTTCATAATGAAGACAATCTTACCATCAAGGAGAGAAACAGTCTTATTGAA
CACATTTTGACATTTGACATGTTAACTGAGTACGTGATATGTACCAGTTATTGGAAGAAGCTGG
AAATACAGACATGATAATACTACAGGCTCTTCCTGTCAGGTGGCCTACGGAGACATTGAAAGTG
TTCCAAATGAAATGATGTAGGAACAGGAATATTAATGCAAAAATGCCATAAGGAAATGAAAAAC
TTTGGAAGATATTATATTGCTGCATCCTATGTGAAGTATCTAGAGTCTGCAGGTGCAAGAGTTA
TACCAATAAGGCTTGATCTTACACATGCAGAATATGAAAAACTTTTCAAATCTATCAATGGAAT
CCTTTTCCCTGGAGGAAGTGTTGACCTTAAGCGCTCAGATTATGCTCAAGTAGCCAAAATATTT
TACGACTTGGCCATACAGAGTTATGATGATGGAGACTATTTTCCTGTGTGGGGCACATGCCTTG
GATTTGAGGAGCTCACTTATCTGGTTAGTGGGGAGTGCTTATTAACTCACACAGAACACACTGT
TGCAGTGACATTGCCGCTGAATTTCACTGGAGCTACATTGCAGAGCAGAATGTTCCAGAATTTT
CCTGCTGACTTGTTGCTGTCATTAGCAACAGAACCCCTGACTGCAAATTTCCACAAATGGAGCC
TTTCCATAAAGAATTTTACGTTGAATGAAAAGTTAAGCAAGTTTTTCAGTGTGTTAACTACGAA
TAGAGATGACAAGATTGAGTTCATTTCATCGATGGAAGGATATAAGTATCCAGTATATGGTGTC
CAGTGGCATCCAGAGAAAGCACCTTATGAATGGGAGAAATTACAAGGCATTTCACATGAACCTA
ATGCTGTGAAGACTGCATTTTATTTAGCAGAGTTCTTTGTTTCTGAAGCTCGGAAAAATGATCA
TCACTTTGAATCTCAATCTGAGGAGGAGAAAGCCCTGATTTATCAGTTCCGTCCAATTTATACT
GGAAATTTTTCTTCATTTCAGCAATGTTATATGTTTGATTGAAAATCTTTGATGTGTTAACAGA
GCACTTTGAATAATTCTGTGATTAAACTATTATAATAACTCATTATTAATGGCAATATTAGAAA
GCTACAGAGATTCCCTTTCTATGTGATTAGCTCTGATTTTTAAATCAATATATGATTTTTTAAA
TCACCTTTGATAATTCATCAGAGACAGATAATCATAGTGTTTTCATGGCAAAGCCTTTATGTCT
GAAGATAGAAAAAAAATGTATTGAGAATTCAAATTTTTTTTCTGATGTACTGATTTTAGAAATA
AATACCACTCCTTACCCATCCATCCCATTTTTATTGGGAGACTTTCATTTTATATTATTATTTA
TGGTGTTGGGGATTGATCTCAGGGTCTTATACATGCTGAACAAGGGCTCTGCTGCTGAGCTACA
TTTCAGCATTAAGAATTTAAATCCTACCTCTATACCCTGGGATGCCTCCCTCCTTTGGGTCTCA
GGATTATGTTGTTGTGTGAGTGGTATGTGTGCAGAGAAACATAAATATCTCCTTTTGCCTCCAT
TTTAGTTCCGCAATTAGAGGGCACACATCCTGCAGACAGTCTGTGCCTTGAACTATTATCTTCT
ATCATGTCTAGTACACAGGCCCTTGATGAACATCTGTGACTACTCGTATTTTCCATATCCATGG
AAAATAATTAAAAAGCTGTCATGCATTGATTTCAGTGCATTTGAATATATTTCTCAATCTGTGC
TATACTCTTTTATCCCTTACCATCCTATATAGACCCTCAAAAGTCTGAAATTTACACATTCCCT
AAGGATAAGCAAGCTGTTAGAAAAAAAAAAGAGGATTTTTTTGACCTGTGTTTAATAAAATGTG
TTTATGCATCTCTTCTTTGTGGTCTTTAGAGCTGCAGCTAGAGAACAAAACCCCAGGAAATTAG
TAAAAACATTGGAGGACATTATGAATGATATTATTTACAGAAAGATAAGAATAATAATCTGAAG
AAACTGAGAGGTAAATCACACTCTTTGAACAAAAAGGATGAATGGAATATAGAAATTGAAAGGA
TTGACAAATTTAGTCAGCCAAGAAAGAACTTTAATAGAAATCTGGCAGACTTAGTTTTTTTTTT
TTTCTTTCTTTTTTTATTATGTCTTGCTGTCTAATGTGCCATTTCTGGCAAGGCTCAAGTCTTC
TACCACTAGAAAAGGTAGTGGCACTATTCCCACTCCCCATACCAGGCCTCTTCCTGACCTTTTG
TTAGAACCATATAGATCTGCTTGTCTCTGCAGAGCCCTAACGGCACTTCACACTGACTGCTCAT
TCATCACTCATGCTGTGTCCATCCTGCCCATGAATATTGACTTCTAGTTGTTTCCGGTGGTTCT
TACTGGGCTTTATTGATGATGCCCACAAATGCAAGAAAATGTAAAAAGATTGTTTCTGCTCATG
TTTAATTTACCATTTTCCATGTACTTTTTTAGAGTCCTCATGCTAGAATCACTTTATTCCCAAA
ATGGGATTTGTTCCAAAGTTGTGTATACCTTGCTTTCCATACTCCATCAGCGATAGGTAAGGGT
TTGAGGACAAATGAGAAGAGCAGGCTGTTCAGGTAGAGAAGGTCCCTCAGTGAGCCAGGTACCA
CTACATCAGTAGGAGCAAGAAGGACATTGATGAGAAAATTTGCCTGTTAATGCTTTGAGCAGCA
GTCTGGAAAACCCTGGGCCTTACAATGTGGAGGGAGCAGAGGCTGAAGGAAAGAGTGGCTGTAG
GAGTGTATATGGATTAGAAAGAGGAACTACAAGAAAGGAAGGATTGGGTAAGCCTGGGCCTTGT
ACATAGAAGAGACAGAAGATGTATTCCCTGCCCCAGCTCACAGCTGATTTCAGTTTCCATGGCT
TTTTAGAAAAAAGTTTTTATCTTCATCATTTCTCATTCTTTTACTTATGTGGAATATCCCAAAT
AGAAAGAAAATGTTGATATTAAGGGCCTTCACTCATTTCTATTCAGCTAGATTGCCCTAAGAAC
CCACAGTTTAGGCCTGGCACTATATTTTATGAGGGCATATTAAGTGTCTCCTCATTTCCACAAA
GCAAAGTAGGGAAATCCTCAAAACCTTGTGCATAGGCCAAGATTCCATGGTTTAGAATGGTCCA
GCAGTTTCTGAAAGCATAGAGATAACTACAGTGGAAGTCTACAAGTCCAGCGCCTGACACACAG
TAGGACCTCAGAGAGTGAGTGCCTTTCCTTCATTTCTCTACCTCTCTGTGATATGGAACGCCTC
CGAATGTGCTGGGTCTCTCTGTTTTTACTCTACAGAATTGTGAGAAAATATACCATTGCAGGGT
TTTCCCAGGGGAAGAGTTAAAAATAAAAGTGCCATTCCTTAGGAACAGAAGCTTTGTTATTATT
TTGTTTGGAGCCTTATTCCAT

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Protein Sequences


Protein RefSeqs	XP_005323027	(Get FASTA)	NCBI Sequence Viewer
	XP_021580588	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000011910.2

RefSeq Acc Id:	XP_005323027 ⟸ XM_005322970
- Peptide Label:	isoform X1
- UniProtKB:	I3MKQ3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASLGRLLCVVGLLLCGAASLGLCKSHTTAAKNPIIGILMQKCHKEMKNFGRYYIAASYVKYLE SAGARVIPIRLDLTHAEYEKLFKSINGILFPGGSVDLKRSDYAQVAKIFYDLAIQSYDDGDYFP VWGTCLGFEELTYLVSGECLLTHTEHTVAVTLPLNFTGATLQSRMFQNFPADLLLSLATEPLTA NFHKWSLSIKNFTLNEKLSKFFSVLTTNRDDKIEFISSMEGYKYPVYGVQWHPEKAPYEWEKLQ GISHEPNAVKTAFYLAEFFVSEARKNDHHFESQSEEEKALIYQFRPIYTGNFSSFQQCYMFD hide sequence

RefSeq Acc Id:

XP_021580588 ⟸ XM_021724913

- Peptide Label:

isoform X2

- Sequence:

show sequence

MQKCHKEMKNFGRYYIAASYVKYLESAGARVIPIRLDLTHAEYEKLFKSINGILFPGGSVDLKR
SDYAQVAKIFYDLAIQSYDDGDYFPVWGTCLGFEELTYLVSGECLLTHTEHTVAVTLPLNFTGA
TLQSRMFQNFPADLLLSLATEPLTANFHKWSLSIKNFTLNEKLSKFFSVLTTNRDDKIEFISSM
EGYKYPVYGVQWHPEKAPYEWEKLQGISHEPNAVKTAFYLAEFFVSEARKNDHHFESQSEEEKA
LIYQFRPIYTGNFSSFQQCYMFD

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RefSeq Acc Id:

ENSSTOP00000011910 ⟸ ENSSTOT00000013288

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000013290	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000013288.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.880	UniProtKB/TrEMBL
InterPro	Class_I_gatase-like	UniProtKB/TrEMBL
	Pept_C26_g-glut_hydrolase	UniProtKB/TrEMBL
	Peptidase_C26	UniProtKB/TrEMBL
NCBI Gene	Ggh	ENTREZGENE
PANTHER	GAMMA-GLUTAMYL HYDROLASE	UniProtKB/TrEMBL
	PTHR11315	UniProtKB/TrEMBL
Pfam	Peptidase_C26	UniProtKB/TrEMBL
PROSITE	GATASE_TYPE_1	UniProtKB/TrEMBL
	PEPTIDASE_C26_GGH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52317	UniProtKB/TrEMBL
UniProt	I3MKQ3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB