| 1304774 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (ortholog); identical protein binding (ortholog); molecular sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to L-arginine (ortholog); negative regulation of TORC1 signaling (ortholog); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 14 | 83309710 | 83314123 | Rat | 90 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312411 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | Predicted to enable several functions, including arginine binding activity; identical protein binding activity; and protein sequestering activity. Predicted to be involved in cellular response to L-arginine; cellular response to amino acid starvation; and regulation of TORC1 signaling. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol. Is expressed in several structures, including Harderian gland; foregut; genitourinary system; skin; and trigeminal nerve. Orthologous to human CASTOR1 (cytosolic arginine sensor for mTORC1 subunit 1). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 4167401 | 4172409 | Mouse | 103 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2306475 | CASTOR1 | cytosolic arginine sensor for mTORC1 subunit 1 | Enables several functions, including arginine binding activity; identical protein binding activity; and protein sequestering activity. Involved in cellular response to L-arginine; cellular response to amino acid starvation; and regulation of TORC1 signaling. Located in GATOR2 complex and cytosol. [p rovided by Alliance of Genome Resources, Jul 2025] | 22 | 30285117 | 30289505 | Human | 83 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8854725 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (ortholog); identical protein binding (ortholog); molecular sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to L-arginine (ortholog); negative regulation of TORC1 signaling (ortholog); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog) | NW_004955455 | 4530842 | 4535358 | Chinchilla | 20 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11820185 | CASTOR1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (inferred); identical protein binding (inferred); molecular sensor activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to L-arginine (inferred); negative regulation of TORC1 signaling (inferred); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (inferred); GATOR2 complex (inferred) | 22 | 11321259 | 11325787 | Bonobo | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12203093 | CASTOR1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (inferred); identical protein binding (inferred); molecular sensor activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to L-arginine (inferred); negative regulation of TORC1 signaling (inferred); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (inferred); GATOR2 complex (inferred) | 26 | 23439472 | 23443950 | Dog | 25 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12546366 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (inferred); identical protein binding (inferred); molecular sensor activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to L-arginine (inferred); negative regulation of TORC1 signaling (inferred); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (inferred); GATOR2 complex (inferred) | NW_004936904 | 372609 | 376878 | Squirrel | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18496202 | CASTOR1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (inferred); identical protein binding (inferred); molecular sensor activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to L-arginine (inferred); negative regulation of TORC1 signaling (inferred); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (inferred); GATOR2 complex (inferred) | | | | Green Monkey | 23 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14030335 | CASTOR1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (inferred); identical protein binding (inferred); molecular sensor activity (inferred); INVOLVED IN cellular response to amino acid starvation (inferred); cellular response to L-arginine (inferred); negative regulation of TORC1 signaling (inferred); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (inferred); GATOR2 complex (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 26 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18901629 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits molecular sensor activity (ortholog); protein sequestering activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to L-arginine (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signa ling pathway; FOUND IN GATOR2 complex (ortholog) | | | | Naked Mole-Rat | 20 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
