| 62071 | Gap43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding; phosphatidylinositol phosphate binding; phosphatidylserine binding; INVOLVED IN nervous system development; regulation of postsynaptic specialization assembly; response to auditory stimulus; PARTICIPATES IN N-cadherin signaling pathway; ASSOCIATED WITH Experimental Seizures; Hearing Loss, Noise-Induced; middle cerebral artery infarction; FOUND IN GABA-ergic synapse; presynapse; axon (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; 17alpha-ethynylestradiol | 11 | 71882131 | 71975799 | Rat | 273 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 730980 | GAP43 | growth associated protein 43 | The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 3 | 115623510 | 115721483 | Human | 272 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 737443 | Gap43 | growth associated protein 43 | Predicted to enable calmodulin binding activity and phospholipid binding activity. Acts upstream of or within cell fate commitment and neurogenesis. Located in several cellular components, including axon; plasma membrane; and postsynaptic density. Is expressed in several structures, including alimen tary system; genitourinary system; musculature; nervous system; and sensory organ. Orthologous to human GAP43 (growth associated protein 43). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 42068915 | 42161014 | Mouse | 291 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8920877 | Gap43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN presynapse; axon (ortholog); cell periphery (ortholog) | NW_004955427 | 15696549 | 15791279 | Chinchilla | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12027684 | GAP43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN GABA-ergic synapse (ortholog); presynapse (ortholog) | 3 | 112765576 | 112863118 | Bonobo | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12194478 | GAP43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN GABA-ergic synapse (ortholog); presynapse (ortholog); INTERACTS WITH bisphenol A | 33 | 19668491 | 19770509 | Dog | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12691648 | Gap43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN cell periphery (ortholog); GABA-ergic synapse (ortholog); presynapse (ortholog) | NW_004936536 | 2995654 | 3091079 | Squirrel | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18912995 | Gap43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN cell periphery (ortholog); GABA-ergic synapse (ortholog); presynapse (ortholog) | | | | Naked Mole-Rat | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18554372 | GAP43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN GABA-ergic synapse (ortholog); presynapse (ortholog) | | | | Green Monkey | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14069133 | GAP43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN GABA-ergic synapse (ortholog); presynapse (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 59 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 625945299 | Gap43 | growth associated protein 43 | ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN axon choice point recognition (ortholog); axon guidance (ortholog); cell fate commitment (ortholog); PARTICIPATES IN N-cadhe rin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Experimental Seizures (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN axon (ortholog); cell periphery (ortholog); cytoplasm (ortholog) | | | | Black Rat | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234853 | gap43 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155234852 | gap43.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155234788 | gap43.S | | | | | | African Clawed Frog | | symbol | gene, null |