Gap43 (growth associated protein 43) - Rat Genome Database

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Gene: Gap43 (growth associated protein 43) Heterocephalus glaber
Analyze
Symbol: Gap43
Name: growth associated protein 43
RGD ID: 18912995
Description: ENCODES a protein that exhibits lysophosphatidic acid binding (ortholog); phosphatidylinositol phosphate binding (ortholog); phosphatidylserine binding (ortholog); INVOLVED IN astrocyte differentiation (ortholog); axon choice point recognition (ortholog); axon guidance (ortholog); PARTICIPATES IN N-cadherin signaling pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); genetic disease (ortholog); Hearing Loss, Noise-Induced (ortholog); FOUND IN cell periphery (ortholog); GABA-ergic synapse (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Neuromodulin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473132,629,477 - 32,749,081 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473132,629,586 - 32,748,515 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gap43
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473132,629,477 - 32,749,081 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473132,629,586 - 32,748,515 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GAP43
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383115,623,510 - 115,721,483 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3115,623,510 - 115,721,490 (+)EnsemblGRCh38hg38GRCh38
GRCh373115,342,357 - 115,440,330 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363116,825,142 - 116,922,842 (+)NCBINCBI36Build 36hg18NCBI36
Build 343116,825,141 - 116,922,842NCBI
Celera3113,750,041 - 113,848,417 (+)NCBICelera
Cytogenetic Map3q13.31NCBI
HuRef3112,715,632 - 112,815,889 (+)NCBIHuRef
CHM1_13115,305,939 - 115,404,101 (+)NCBICHM1_1
T2T-CHM13v2.03118,343,657 - 118,441,697 (+)NCBIT2T-CHM13v2.0
Gap43
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391642,068,915 - 42,161,014 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1642,068,805 - 42,161,014 (-)EnsemblGRCm39 Ensembl
GRCm381642,248,552 - 42,340,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1642,248,442 - 42,340,651 (-)EnsemblGRCm38mm10GRCm38
MGSCv371642,248,665 - 42,340,764 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361642,167,884 - 42,259,983 (-)NCBIMGSCv36mm8
Celera1642,611,179 - 42,699,387 (-)NCBICelera
Cytogenetic Map16B4NCBI
cM Map1628.37NCBI
Gap43
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81171,882,131 - 71,975,799 (+)NCBIGRCr8
mRatBN7.21158,376,371 - 58,470,047 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1158,376,371 - 58,470,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1167,189,389 - 67,283,059 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01159,851,686 - 59,945,352 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01158,895,119 - 58,988,732 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01158,624,198 - 58,717,916 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1158,624,198 - 58,717,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01162,777,623 - 62,870,998 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,989,085 - 60,083,971 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11160,046,673 - 60,141,558 (+)NCBI
Celera1157,921,205 - 58,014,789 (+)NCBICelera
Cytogenetic Map11q21NCBI
Gap43
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542715,695,963 - 15,791,327 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542715,696,549 - 15,791,279 (+)NCBIChiLan1.0ChiLan1.0
GAP43
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22113,616,249 - 113,716,525 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13113,621,025 - 113,721,301 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03112,765,576 - 112,863,118 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13119,682,743 - 119,780,290 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3119,734,942 - 119,780,290 (+)Ensemblpanpan1.1panPan2
GAP43
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13319,668,491 - 19,770,509 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3319,656,835 - 19,770,408 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3319,775,530 - 19,877,471 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03319,917,865 - 20,017,414 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3319,917,886 - 20,017,410 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13319,722,015 - 19,823,783 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03319,768,803 - 19,870,740 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03320,313,727 - 20,415,899 (+)NCBIUU_Cfam_GSD_1.0
Gap43
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602134,430,958 - 134,526,139 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365362,995,654 - 3,091,079 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAP43
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13144,364,317 - 144,629,174 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113144,364,314 - 144,458,136 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213153,842,841 - 153,937,719 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAP43
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12265,142,472 - 65,242,185 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2265,142,039 - 65,242,222 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041101,151,539 - 101,250,605 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020131   ⟹   ENSHGLP00000019931
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473132,629,477 - 32,749,081 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000020132   ⟹   ENSHGLP00000019932
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473132,629,477 - 32,749,081 (-)Ensembl
RefSeq Acc Id: XM_004835680   ⟹   XP_004835737
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473132,629,586 - 32,748,515 (-)NCBI
RefSeq Acc Id: XM_004835681   ⟹   XP_004835738
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473132,629,586 - 32,748,418 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004835737 (Get FASTA)   NCBI Sequence Viewer  
  XP_004835738 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98380 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019931
  ENSHGLP00000019932
  ENSHGLP00100057311
GenBank Protein JAN97739 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004835737   ⟸   XM_004835680
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004835738   ⟸   XM_004835681
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J110 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019932   ⟸   ENSHGLT00000020132
RefSeq Acc Id: ENSHGLP00000019931   ⟸   ENSHGLT00000020131


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014273 Ensembl, ENTREZGENE
  ENSHGLG00100045653 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000020131 ENTREZGENE
  ENSHGLT00000020132 ENTREZGENE
  ENSHGLT00100044707 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.190 UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Neuromodulin UniProtKB/TrEMBL
  Neuromodulin_C UniProtKB/TrEMBL
  Neuromodulin_gap-junction_N UniProtKB/TrEMBL
  Neuromodulin_P_site UniProtKB/TrEMBL
  Neuromodulin_palmitoyl_site UniProtKB/TrEMBL
NCBI Gene Gap43 ENTREZGENE
PANTHER NEUROMODULIN UniProtKB/TrEMBL
  NEUROMODULIN UniProtKB/TrEMBL
Pfam Neuromodulin UniProtKB/TrEMBL
  Neuromodulin_N UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
PRINTS NEUROMODULIN UniProtKB/TrEMBL
PROSITE NEUROMODULIN_1 UniProtKB/TrEMBL
  NEUROMODULIN_2 UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
SMART SM00015 UniProtKB/TrEMBL
UniProt A0A0P6J110 ENTREZGENE, UniProtKB/TrEMBL