| 1346340 | FTL | ferritin light chain | This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008] | 19 | 48965309 | 48966879 | Human | 575 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 9067917 | Ftl | ferritin light chain | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholog); Chemical and Drug Induced Live r Injury (ortholog); FOUND IN autolysosome (ortholog); ferritin complex (ortholog) | NW_004955559 | 1691722 | 1693381 | Chinchilla | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11725000 | FTL | ferritin light chain | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholog); Chemical and Drug Induced Live r Injury (ortholog); FOUND IN ferritin complex (ortholog) | 19 | 45966431 | 45968015 | Bonobo | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12419544 | FTL | ferritin light chain | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholog); Chemical and Drug Induced Live r Injury (ortholog); FOUND IN ferritin complex (ortholog) | 1 | 107418457 | 107419923 | Dog | 54 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12658057 | Ftl | ferritin light chain | ENCODES a protein that exhibits ferric iron binding (inferred); ferrous iron binding (inferred); identical protein binding (inferred); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortho log); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | NW_004936664 | 2976325 | 2977878 | Squirrel | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14236832 | FTL | ferritin light chain | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholog); Chemical and Drug Induced Live r Injury (ortholog); FOUND IN ferritin complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 55 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18760751 | FTL | ferritin light chain | ENCODES a protein that exhibits ferric iron binding (inferred); ferrous iron binding (inferred); identical protein binding (inferred); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortho log); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | | | | Green Monkey | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18922800 | Ftl | ferritin light chain | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholog); Chemical and Drug Induced Live r Injury (ortholog); FOUND IN ferritin complex (ortholog) | | | | Naked Mole-Rat | 53 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 625856272 | Ftl | ferritin light chain | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion (ortholog); PARTICIPATES IN iron storage pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholog); Chemical and Drug Induced Live r Injury (ortholog); FOUND IN autolysosome (ortholog); ferritin complex (ortholog) | | | | Black Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 61813 | Ftl1 | ferritin light chain 1 | ENCODES a protein that exhibits identical protein binding (ortholog); iron ion binding (ortholog); INVOLVED IN response to lead ion; PARTICIPATES IN iron storage pathway; porphyrin and chlorophyll metabolic pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); basal ganglia disease (ortholo g); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN autolysosome (ortholog); ferritin complex (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 1 | 105072858 | 105074705 | Rat | 433 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 62105 | Ftl1 | ferritin light polypeptide 1 | Predicted to enable ferric iron binding activity; ferrous iron binding activity; and identical protein binding activity. Predicted to be involved in intracellular iron ion homeostasis and iron ion transport. Predicted to be located in autolysosome. Predicted to be part of ferritin complex. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; ciliary body; liver; and retina nuclear layer. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 45107368 | 45109310 | Mouse | 448 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 7182454 | Ftl1-ps2 | ferritin light polypeptide, pseudogene 2 | Predicted to enable identical protein binding activity and iron ion binding activity. Predicted to be part of ferritin complex. [provided by Alliance of Genome Resources, Apr 2025] | 10 | 130427835 | 130428771 | Mouse | | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1624090 | Ftl2-ps | ferritin light polypeptide 2, pseudogene | Predicted to enable ferric iron binding activity; ferrous iron binding activity; and identical protein binding activity. Predicted to be part of ferritin complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndr ome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 125397873 | 125398811 | Mouse | 16 | symbol , PhenoGen , description , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 16565462 | AC174071.1 | ferritin, light polypeptide (FTL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16565455 | AL096855.2 | ferritin, light polypeptide (FTL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16561200 | AP003174.3 | ferritin, light polypeptide (FTL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16561738 | FTLP20 | ferritin light chain pseudogene 20 | | 15 | 92762757 | 92763793 | Human | | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077587 | FTLP9 | ferritin light chain pseudogene 9 | | 4 | 77216419 | 77216866 | Human | | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1350618 | FTLP1 | ferritin light chain pseudogene 1 | | 20 | 45975117 | 45976268 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1353556 | FTLP2 | ferritin light chain pseudogene 2 | INTERACTS WITH arsane; arsenic atom; bisphenol A | X | 30630097 | 30630969 | Human | 8 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 1606917 | FTLP3 | ferritin light chain pseudogene 3 | INTERACTS WITH 5-fluorouracil; cadmium dichloride; cisplatin | 20 | 4023718 | 4024588 | Human | 8 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 3322053 | FTLP4 | ferritin light chain pseudogene 4 | | 9 | 30934587 | 30936005 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3539546 | FTLP5 | ferritin light chain pseudogene 5 | | 19 | 3870794 | 3872207 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077588 | FTLP6 | ferritin light chain pseudogene 6 | | 11 | 66771449 | 66771870 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3436675 | FTLP7 | ferritin light chain pseudogene 7 | | 11 | 115538718 | 115539583 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077572 | FTLP8 | ferritin light chain pseudogene 8 | | 13 | 97986949 | 97987225 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1561055 | Ftl1l1 | ferritin light chain 1 like 1 | ENCODES a protein that exhibits ferric iron binding (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred); INTERACTS WITH ammonium chlo ride; bisphenol A; rotenone | X | 136686721 | 136687633 | Rat | 13 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2325062 | Ftl1l2 | ferritin light chain 1 like 2 | ENCODES a protein that exhibits ferric iron binding (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred); INTERACTS WITH cadmium atom | 6 | 78977712 | 78987254 | Rat | 11 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 9187193 | Ftl1l3 | ferritin light chain 1 like 3 | | 15 | 91249140 | 91249574 | Rat | | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1592032 | Ftl1l4 | ferritin light chain 1 like 4 | | 2 | 146762350 | 146763451 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1560687 | Ftl1l5 | ferritin light chain 1 like 5 | ENCODES a protein that exhibits ferric iron binding (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred); INTERACTS WITH bisphenol A; lidocaine; rotenone | 7 | 12295404 | 12871512 | Rat | 15 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1561520 | Ftl1l6 | ferritin light chain 1 like 6 | INTERACTS WITH bisphenol A; furan; rotenone | 2 | 53124485 | 53126902 | Rat | 3 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1566189 | Ftl1l7 | ferritin light chain 1 like 7 | ENCODES a protein that exhibits ferric iron binding (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred); INTERACTS WITH ammonium chlo ride; bisphenol A; Monobutylphthalate | 1 | 174812313 | 174813134 | Rat | 15 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 3129621 | FTLP10 | ferritin light chain pseudogene 10 | INTERACTS WITH benzo[a]pyrene; bisphenol A; fulvestrant | 4 | 68182292 | 68212470 | Human | 3 | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 3457134 | FTLP11 | ferritin light chain pseudogene 11 | | 15 | 28857786 | 28858498 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077558 | FTLP12 | ferritin light chain pseudogene 12 | INTERACTS WITH acrylamide; beta-lapachone; sodium arsenite | 17 | 16391434 | 16391883 | Human | 3 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077571 | FTLP13 | ferritin light chain pseudogene 13 | | 17 | 22221220 | 22221645 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077557 | FTLP14 | ferritin light chain pseudogene 14 | INTERACTS WITH beta-lapachone | 16 | 68822449 | 68823232 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3302433 | FTLP15 | ferritin light chain pseudogene 15 | | 7 | 45997387 | 45998274 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3231815 | FTLP16 | ferritin light chain pseudogene 16 | | X | 38484761 | 38485264 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3184433 | FTLP17 | ferritin light chain pseudogene 17 | | 1 | 104153329 | 104154037 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3077584 | FTLP18 | ferritin light chain pseudogene 18 | | 1 | 36630335 | 36630812 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6481426 | FTLP19 | ferritin light chain pseudogene 19 | | 10 | 16071416 | 16071809 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 2301792 | Ftl1-ps1 | ferritin light polypeptide 1, pseudogene 1 | INTERACTS WITH (1->4)-beta-D-glucan; 2,3',4,4',5-Pentachlorobiphenyl; diquat | 13 | 74554516 | 74555444 | Mouse | 5 | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 6500416 | Ftl1-ps1 | ferritin light chain 1, pseudogene 1 | | 1 | 110059548 | 110060422 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40952038 | Ftl1-ps2 | ferritin light chain 1, pseudogene 2 | | 6 | 116720675 | 116725472 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1588517 | Ftl1-ps3 | ferritin light chain 1, pseudogene 3 | | 18 | 29701035 | 29702054 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1586116 | Ftl1-ps4 | ferritin light chain 1, pseudogene 4 | | 1 | 9236915 | 9249333 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1591990 | Ftl1-ps5 | ferritin light chain 1, pseudogene 5 | | 8 | 129117473 | 129118195 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41216689 | Ftl1-ps6 | ferritin light chain 1, pseudogene 6 | | 7 | 8483630 | 8484178 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40982949 | Ftl1-ps7 | ferritin light chain 1, pseudogene 7 | | 7 | 70192161 | 70192818 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40939206 | Ftl1-ps8 | ferritin light chain 1, pseudogene 8 | | 7 | 62710859 | 62723054 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41231727 | Ftl1-ps9 | ferritin light chain 1, pseudogene 9 | | 9 | 112964806 | 112967633 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40961797 | Ftl1-ps10 | ferritin light chain 1, pseudogene 10 | | 10 | 101301934 | 101302534 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40941817 | Ftl1-ps11 | ferritin light chain 1, pseudogene 11 | | 13 | 41043124 | 41044978 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41231025 | Ftl1-ps12 | ferritin light chain 1, pseudogene 12 | | 1 | 86215048 | 86223978 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 41326583 | Ftl1-ps13 | ferritin light chain 1, pseudogene 13 | | X | 45399355 | 45399915 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 2324713 | Ftl1-ps14 | ferritin light chain 1, pseudogene 14 | ENCODES a pseudogene that exhibits ferric iron binding (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN autolysosome (inferred); INTERACTS WITH bisphenol A | 2 | 63270586 | 63271499 | Rat | 6 | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 11883464 | LOC100971948 | ferritin light chain | ENCODES a protein that exhibits ferric iron binding (inferred); ferrous iron binding (inferred); metal ion binding (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN autolysosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferr ed) | 11 | 43650332 | 43651204 | Bonobo | 10 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1558100 | Rspo2 | R-spondin 2 | Enables heparin binding activity. Acts upstream of or within several processes, including embryonic limb morphogenesis; negative regulation of odontogenesis of dentin-containing tooth; and respiratory system development. Located in cell surface and extracellular region. Is expressed in several struc tures, including brain; jaw; limb; pelvic urethra; and sensory organ. Human ortholog(s) of this gene implicated in tetraamelia syndrome 2. Orthologous to human RSPO2 (R-spondin 2). [provided by Alliance of Genome Resources, Apr 2025] | 15 | 42884184 | 43034990 | Mouse | 210 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2322860 | LOC100360087 | ferritin light chain 1-like | ENCODES a protein that exhibits iron ion binding (ortholog); INVOLVED IN intracellular iron ion homeostasis (inferred); iron ion transport (inferred); FOUND IN ferritin complex (ortholog) | 5 | 151606496 | 151607413 | Rat | 13 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |