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Gene: Rspo2 (R-spondin 2) Mus musculus
Symbol: Rspo2
Name: R-spondin 2
Description: Exhibits heparin binding activity. Involved in several processes, including embryonic limb morphogenesis; negative regulation of odontogenesis of dentin-containing tooth; and respiratory system development. Localizes to the cell surface and extracellular region. Is expressed in several structures, including brain; jaw; limb; musculoskeletal system; and pelvic urethra. Orthologous to human RSPO2 (R-spondin 2); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610028F08Rik; AA673245; cristin-2; cysteine-rich and single thrombospondin domain-containing protein 2; D430027K22; ftls; mCristin-2; R-spondin 2 homolog; R-spondin-2; roof plate-specific spondin-2
Homo sapiens (human) : RSPO2 (R-spondin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rspo2 (R-spondin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rspo2 (R-spondin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RSPO2 (R-spondin 2)
Canis lupus familiaris (dog) : RSPO2 (R-spondin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rspo2 (R-spondin 2)
Sus scrofa (pig) : RSPO2 (R-spondin 2)
Chlorocebus sabaeus (green monkey) : RSPO2 (R-spondin 2)
Heterocephalus glaber (naked mole-rat) : Rspo2 (R-spondin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1543,020,794 - 43,170,826 (-)Ensembl
GRCm381543,020,788 - 43,171,594 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371542,852,341 - 43,002,364 (-)NCBIGRCm37mm9NCBIm37
MGSCv361542,850,869 - 43,000,892 (-)NCBImm8
Celera1543,503,080 - 43,653,511 (-)NCBICelera
Cytogenetic Map15 B3.1-B3.2NCBI
cM Map1516.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rspo2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558100
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.