Folr1 Gene Search Result

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17 records found for search term Folr1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
71032	Folr1	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (ortholog); folic acid receptor activity (ortholog); INVOLVED IN anterior neural tube closure (ortholog); axon regeneration (ortholog); cardiac neural crest cell migration involved in outflow tract morphogenesis (ortholog); PARTICIPATES IN altered f ... (more) olate cycle metabolic pathway; folate cycle metabolic pathway; endocytosis pathway; ASSOCIATED WITH cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN brush border membrane; apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol	1	165631462	165650430	Rat	215	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
734402	Folr1	folate receptor alpha	Enables folic acid receptor activity. Involved in several processes, including circulatory system development; nervous system development; and regulation of signal transduction. Acts upstream of or within folic acid metabolic process. Is active in plasma membrane. Is expressed in several structures, ... (more) including brain; early conceptus; genitourinary system; gut; and retina. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Orthologous to human FOLR1 (folate receptor alpha). [provided by Alliance of Genome Resources, Jul 2025]	7	101507551	101519974	Mouse	251	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1346305	FOLR1	folate receptor alpha	The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidyl ... (more) inositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]	11	72189709	72196323	Human	269	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
8822238	Folr1	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (ortholog); folic acid receptor activity (ortholog); INVOLVED IN anterior neural tube closure (ortholog); axon regeneration (ortholog); cardiac neural crest cell migration involved in outflow tract morphogenesis (ortholog); PARTICIPATES IN altered f ... (more) olate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog)	NW_004955414	19188830	19197728	Chinchilla	42	symbol	gene, protein-coding, MODEL [RefSeq]
12461629	Folr1	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (inferred); folic acid receptor activity (inferred); signaling receptor activity (inferred); INVOLVED IN folic acid metabolic process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH ... (more) cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN brush border membrane (ortholog)	NW_004936498	1489916	1497200	Squirrel	46	symbol	gene, protein-coding, MODEL [RefSeq]
13921992	FOLR1	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (inferred); folic acid receptor activity (inferred); INVOLVED IN folic acid metabolic process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH cerebral folate receptor alpha deficien ... (more) cy (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN brush border membrane (ortholog)				Pig	46	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
155240120	folr1						Tropical Clawed Frog		symbol	gene, null
18499275	FOLR1	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (inferred); folic acid receptor activity (inferred); signaling receptor activity (inferred); INVOLVED IN folic acid metabolic process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH ... (more) cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN brush border membrane (ortholog)				Green Monkey	46	symbol	gene, protein-coding, MODEL [RefSeq]
18924755	Folr1	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (ortholog); folic acid receptor activity (ortholog); INVOLVED IN anterior neural tube closure (ortholog); axon regeneration (ortholog); cardiac neural crest cell migration involved in outflow tract morphogenesis (ortholog); PARTICIPATES IN altered f ... (more) olate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog)				Naked Mole-Rat	46	symbol	gene, protein-coding, MODEL [RefSeq]
155240121	folr1.L						African Clawed Frog		symbol	gene, null
616336042	FOLR1-AS1	FOLR1 antisense RNA 1		11	72163322	72209241	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
1318329	FOLR2	folate receptor beta	The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolat ... (more) e to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]	11	72216794	72221950	Human	118	description , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
14262562	FOLR3	folate receptor gamma	ASSOCIATED WITH COVID-19 (ortholog)				Pig	7	old_gene_symbol	gene, protein-coding, PROVISIONAL [RefSeq]
12014450	LOC100994139	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (inferred); folic acid receptor activity (inferred); signaling receptor activity (inferred); INVOLVED IN folic acid metabolic process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH ... (more) cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN brush border membrane (ortholog)	11	67268721	67275498	Bonobo	46	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
12287675	LOC609612	folate receptor alpha	ENCODES a protein that exhibits folic acid binding (ortholog); folic acid receptor activity (ortholog); INVOLVED IN anterior neural tube closure (ortholog); axon regeneration (ortholog); cardiac neural crest cell migration involved in outflow tract morphogenesis (ortholog); PARTICIPATES IN altered f ... (more) olate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog)	21	25944350	25951010	Dog	47	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
16561064	AP000812.3	folate receptor 1 (adult) (FOLR1) pseudogene					Human		name	gene, unprocessed_pseudogene
1349897	FOLR1P1	folate receptor 1 pseudogene 1		11	72158833	72159656	Human		symbol , GTEx , COSMIC , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]