LOC609612 (folate receptor alpha) - Rat Genome Database

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Gene: LOC609612 (folate receptor alpha) Canis lupus familiaris
Analyze
Symbol: LOC609612
Name: folate receptor alpha
RGD ID: 12287675
Description: ENCODES a protein that exhibits folic acid binding (ortholog); INVOLVED IN folic acid metabolic process (ortholog); renal absorption (ortholog); response to folic acid (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; folate cycle metabolic pathway; ASSOCIATED WITH cerebral folate receptor alpha deficiency (ortholog); Colonic Neoplasms (ortholog); Congenital Abnormalities (ortholog); FOUND IN brush border (ortholog); brush border membrane (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: folate receptor 1; folate receptor 1 (adult); FOLR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,944,350 - 25,951,010 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,714,017 - 25,720,656 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,153,187 - 26,159,847 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,153,297 - 26,159,800 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,944,449 - 25,951,109 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,160,593 - 26,167,256 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,062,191 - 26,068,851 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
LOC609612
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12125,944,350 - 25,951,010 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2125,714,017 - 25,720,656 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02126,153,187 - 26,159,847 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2126,153,297 - 26,159,800 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12125,944,449 - 25,951,109 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02126,160,593 - 26,167,256 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02126,062,191 - 26,068,851 (-)NCBIUU_Cfam_GSD_1.0
FOLR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381172,189,709 - 72,196,323 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1172,189,558 - 72,196,323 (+)EnsemblGRCh38hg38GRCh38
GRCh371171,900,753 - 71,907,367 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,578,250 - 71,585,014 (+)NCBINCBI36Build 36hg18NCBI36
Build 341171,580,855 - 71,585,014NCBI
Celera1169,202,176 - 69,208,941 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1168,193,609 - 68,200,378 (+)NCBIHuRef
CHM1_11171,784,063 - 71,790,828 (+)NCBICHM1_1
T2T-CHM13v2.01172,116,250 - 72,122,864 (+)NCBIT2T-CHM13v2.0
Folr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397101,507,538 - 101,519,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7101,507,538 - 101,519,995 (-)EnsemblGRCm39 Ensembl
GRCm387101,858,331 - 101,870,788 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7101,858,331 - 101,870,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv377109,006,845 - 109,019,197 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367101,732,152 - 101,744,504 (-)NCBIMGSCv36mm8
Celera7102,230,147 - 102,242,481 (-)NCBICelera
Cytogenetic Map7E2NCBI
Folr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21156,219,460 - 156,238,436 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1156,219,460 - 156,230,667 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,209,769 - 164,220,975 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01171,389,863 - 171,401,069 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01164,267,520 - 164,278,567 (-)NCBIRnor_WKY
Rnor_6.01166,934,457 - 166,945,864 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,934,460 - 166,943,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01173,124,242 - 173,135,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,315,191 - 159,324,141 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11159,394,208 - 159,403,158 (-)NCBI
Celera1154,298,870 - 154,310,077 (-)NCBICelera
Cytogenetic Map1q32NCBI
Folr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541419,187,388 - 19,197,728 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541419,188,830 - 19,197,728 (-)NCBIChiLan1.0ChiLan1.0
FOLR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11170,492,039 - 70,498,665 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1170,492,039 - 70,498,665 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01167,268,721 - 67,275,498 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Folr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494759,892,012 - 59,897,666 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364981,489,916 - 1,497,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOLR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl96,757,040 - 6,760,402 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.196,753,513 - 6,760,433 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.297,515,002 - 7,521,923 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOLR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,405,513 - 63,413,372 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,406,597 - 63,413,352 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604362,470,494 - 62,476,997 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Folr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248174,820,163 - 4,851,339 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248174,830,164 - 4,850,565 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 22 6 6 6 6 12 10 6
Low 5 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005633554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038568769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038632942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_846900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00845018242   ⟹   ENSCAFP00845014229
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2126,153,297 - 26,159,800 (-)Ensembl
RefSeq Acc Id: XM_005633554   ⟹   XP_005633611
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,944,350 - 25,951,009 (-)NCBI
Dog10K_Boxer_Tasha2125,714,017 - 25,720,655 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022407744   ⟹   XP_022263452
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,944,350 - 25,951,010 (-)NCBI
Dog10K_Boxer_Tasha2125,714,017 - 25,720,656 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038430259   ⟹   XP_038286187
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,153,187 - 26,159,846 (-)NCBI
RefSeq Acc Id: XM_038430260   ⟹   XP_038286188
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,153,187 - 26,159,847 (-)NCBI
RefSeq Acc Id: XM_038430261   ⟹   XP_038286189
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02126,153,187 - 26,159,846 (-)NCBI
RefSeq Acc Id: XM_038505587   ⟹   XP_038361515
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12125,944,449 - 25,951,108 (-)NCBI
RefSeq Acc Id: XM_038505588   ⟹   XP_038361516
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12125,944,449 - 25,951,109 (-)NCBI
RefSeq Acc Id: XM_038505589   ⟹   XP_038361517
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12125,944,449 - 25,951,108 (-)NCBI
RefSeq Acc Id: XM_038568767   ⟹   XP_038424695
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,062,191 - 26,068,850 (-)NCBI
RefSeq Acc Id: XM_038568768   ⟹   XP_038424696
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,062,191 - 26,068,851 (-)NCBI
RefSeq Acc Id: XM_038568769   ⟹   XP_038424697
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02126,062,191 - 26,068,850 (-)NCBI
RefSeq Acc Id: XM_038632940   ⟹   XP_038488868
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,160,593 - 26,167,255 (-)NCBI
RefSeq Acc Id: XM_038632941   ⟹   XP_038488869
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,160,593 - 26,167,256 (-)NCBI
RefSeq Acc Id: XM_038632942   ⟹   XP_038488870
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02126,160,593 - 26,167,255 (-)NCBI
RefSeq Acc Id: XM_846900   ⟹   XP_851993
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12125,944,350 - 25,951,010 (-)NCBI
Dog10K_Boxer_Tasha2125,714,017 - 25,720,652 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_851993   ⟸   XM_846900
- UniProtKB: E2QXC4 (UniProtKB/TrEMBL),   A0A8C0QVE5 (UniProtKB/TrEMBL),   A0A8C0Z2T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005633611   ⟸   XM_005633554
- UniProtKB: E2QXC4 (UniProtKB/TrEMBL),   A0A8C0QVE5 (UniProtKB/TrEMBL),   A0A8C0Z2T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022263452   ⟸   XM_022407744
- UniProtKB: A0A8C0QVE5 (UniProtKB/TrEMBL),   A0A8C0Z2T7 (UniProtKB/TrEMBL),   E2QXC4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038361516   ⟸   XM_038505588
RefSeq Acc Id: XP_038361517   ⟸   XM_038505589
RefSeq Acc Id: XP_038361515   ⟸   XM_038505587
RefSeq Acc Id: XP_038488869   ⟸   XM_038632941
RefSeq Acc Id: XP_038488870   ⟸   XM_038632942
RefSeq Acc Id: XP_038488868   ⟸   XM_038632940
RefSeq Acc Id: XP_038286188   ⟸   XM_038430260
- UniProtKB: A0A8C0QVE5 (UniProtKB/TrEMBL),   A0A8C0Z2T7 (UniProtKB/TrEMBL),   E2QXC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286189   ⟸   XM_038430261
- UniProtKB: A0A8C0QVE5 (UniProtKB/TrEMBL),   A0A8C0Z2T7 (UniProtKB/TrEMBL),   E2QXC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286187   ⟸   XM_038430259
- UniProtKB: A0A8C0QVE5 (UniProtKB/TrEMBL),   A0A8C0Z2T7 (UniProtKB/TrEMBL),   E2QXC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424696   ⟸   XM_038568768
RefSeq Acc Id: XP_038424697   ⟸   XM_038568769
RefSeq Acc Id: XP_038424695   ⟸   XM_038568767
RefSeq Acc Id: ENSCAFP00845014229   ⟸   ENSCAFT00845018242
Protein Domains
Folate_rec

Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
21 25947400 25947401 G C snv Chinese indigenous dogs (DQ9)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030009803 UniProtKB/TrEMBL
  ENSCAFG00040020309 UniProtKB/TrEMBL
  ENSCAFG00845010357 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030015819.1 UniProtKB/TrEMBL
  ENSCAFP00040032744 UniProtKB/TrEMBL
  ENSCAFP00845014229 ENTREZGENE
  ENSCAFP00845014229.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030018116.1 UniProtKB/TrEMBL
  ENSCAFT00040037566 UniProtKB/TrEMBL
  ENSCAFT00845018242 ENTREZGENE
  ENSCAFT00845018242.1 UniProtKB/TrEMBL
InterPro Folate_rcpt UniProtKB/TrEMBL
  Folate_rcpt-like UniProtKB/TrEMBL
  FOLR1 UniProtKB/TrEMBL
NCBI Gene LOC609612 ENTREZGENE
PANTHER PTHR10517 UniProtKB/TrEMBL
  PTHR10517:SF15 UniProtKB/TrEMBL
Pfam Folate_rec UniProtKB/TrEMBL
UniProt A0A8C0QVE5 ENTREZGENE
  A0A8C0Z2T7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3N9V0_CANLF UniProtKB/TrEMBL
  E2QXC4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC609612  folate receptor alpha  FOLR1  folate receptor alpha  Symbol and/or name change 5135510 APPROVED
2019-05-14 FOLR1  folate receptor alpha  FOLR1  folate receptor 1  Symbol and/or name change 5135510 APPROVED
2017-09-12 FOLR1  folate receptor 1  LOC609612  folate receptor alpha  Symbol and/or name change 5135510 APPROVED