Fbxw11 Gene Search Result

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13 records found for search term Fbxw11

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1309121	Fbxw11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation ... (more) of canonical NF-kappaB signal transduction (ortholog); positive regulation of circadian rhythm (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride	10	17737181	17834834	Rat	106	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1319284	FBXW11	F-box and WD repeat domain containing 11	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ub ... (more) iquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq, Jul 2008]	5	171861549	172006638	Human	175	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1553129	Fbxw11	F-box and WD-40 domain protein 11	Enables ubiquitin-protein transferase activity. Contributes to ubiquitin protein ligase activity. Involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of non-canonical NF-kappaB signal transduction; and protein modifica ... (more) tion process. Located in cytosol and nucleus. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including genitourinary system and yolk sac. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11). [provided by Alliance of Genome Resources, Apr 2025]	11	32592595	32696816	Mouse	130	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8889286	Fbxw11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation ... (more) of canonical NF-kappaB signal transduction (ortholog); positive regulation of circadian rhythm (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)	NW_004955408	24703477	24834522	Chinchilla	54	symbol	gene, protein-coding, MODEL [RefSeq]
11932880	FBXW11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits protein dimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); proteasome-mediated ubiquitin-de ... (more) pendent protein catabolic process (ortholog); protein dephosphorylation (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog)	5	167207643	167354730	Bonobo	58	symbol	gene, protein-coding, MODEL [RefSeq]
12423094	FBXW11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein dephosphorylation (ortholog); PART ... (more) ICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog)	4	40238695	40363445	Dog	71	symbol	gene, protein-coding, MODEL [RefSeq]
12547135	Fbxw11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein dephosphorylation (ortholog); PART ... (more) ICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog)	NW_004936609	3256658	3341918	Squirrel	57	symbol	gene, protein-coding, MODEL [RefSeq]
13976549	FBXW11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits protein dimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-protein transferase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); proteasome-mediated ubiquitin-dependent pr ... (more) otein catabolic process (ortholog); protein dephosphorylation (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog)				Pig	57	symbol	gene, protein-coding, MODEL [RefSeq]
18557749	FBXW11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits protein dimerization activity (inferred); ubiquitin protein ligase activity (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); proteasome-mediated ubiquitin-de ... (more) pendent protein catabolic process (ortholog); protein dephosphorylation (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog)				Green Monkey	57	symbol	gene, protein-coding, MODEL [RefSeq]
625901242	Fbxw11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation ... (more) of canonical NF-kappaB signal transduction (ortholog); positive regulation of circadian rhythm (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)				Black Rat	54	symbol	gene, protein-coding, MODEL [RefSeq]
18910814	Fbxw11	F-box and WD repeat domain containing 11	ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); ubiquitin-like ligase-substrate adaptor activity (ortholog); INVOLVED IN negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation of canonical NF-kappaB signal transduction (orthol ... (more) og); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)				Naked Mole-Rat	54	symbol	gene, protein-coding, MODEL [RefSeq]
7631858	Fbxw11-ps1	F-box and WD repeat domain containing 11, pseudogene 1		1	125834226	125852464	Rat		symbol , PhenoGen	gene, pseudo, MODEL [RefSeq]
1349057	FBXW11P1	F-box and WD repeat domain containing 11 pseudogene 1	INTERACTS WITH okadaic acid	21	31627057	31628660	Human	1	symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]