Fbxw11 (F-box and WD repeat domain containing 11) - Rat Genome Database

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Gene: Fbxw11 (F-box and WD repeat domain containing 11) Heterocephalus glaber
Analyze
Symbol: Fbxw11
Name: F-box and WD repeat domain containing 11
RGD ID: 18910814
Description: ENCODES a protein that exhibits ubiquitin ligase-substrate adaptor activity (ortholog); ubiquitin protein ligase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH genetic disease (ortholog); NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROME (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box/WD repeat-containing protein 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473317,985,546 - 18,121,398 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Fbxw11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473317,985,546 - 18,121,398 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FBXW11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,861,549 - 172,006,638 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,861,549 - 172,006,873 (-)EnsemblGRCh38hg38GRCh38
GRCh375171,288,553 - 171,433,642 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,221,161 - 171,366,482 (-)NCBINCBI36Build 36hg18NCBI36
Celera5167,321,013 - 167,466,463 (-)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5166,384,918 - 166,530,978 (-)NCBIHuRef
CHM1_15170,721,014 - 170,866,350 (-)NCBICHM1_1
T2T-CHM13v2.05172,401,847 - 172,546,952 (-)NCBIT2T-CHM13v2.0
Fbxw11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,592,595 - 32,696,816 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,592,724 - 32,696,816 (+)EnsemblGRCm39 Ensembl
GRCm381132,642,555 - 32,746,816 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,642,724 - 32,746,816 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,542,875 - 32,646,816 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,542,875 - 32,646,816 (+)NCBIMGSCv36mm8
Celera1135,097,954 - 35,164,258 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.02NCBI
Fbxw11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,737,181 - 17,834,834 (+)NCBIGRCr8
mRatBN7.21017,232,735 - 17,330,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1021,981,943 - 22,079,366 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,470,550 - 21,567,952 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,958,675 - 17,056,257 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,542,374 - 17,640,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,430,246 - 17,528,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,502,480 - 17,600,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11017,503,612 - 17,599,012 (+)NCBI
Celera1016,877,301 - 16,974,446 (+)NCBICelera
Cytogenetic Map10q12NCBI
Fbxw11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,687,493 - 24,834,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540824,703,477 - 24,834,522 (-)NCBIChiLan1.0ChiLan1.0
FBXW11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,996,014 - 167,146,079 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15165,135,553 - 165,285,624 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05167,207,643 - 167,354,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15174,124,499 - 174,271,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5174,124,499 - 174,271,977 (-)Ensemblpanpan1.1panPan2
FBXW11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,238,695 - 40,363,445 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,238,737 - 40,361,125 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,187,588 - 40,312,355 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0440,613,819 - 40,738,727 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,613,835 - 40,738,782 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,429,468 - 40,554,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,619,623 - 40,744,342 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,129,822 - 41,254,632 (+)NCBIUU_Cfam_GSD_1.0
Fbxw11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,508,434 - 94,619,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,256,657 - 3,341,994 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,256,658 - 3,341,918 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXW11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,212,607 - 52,337,913 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11652,212,401 - 52,337,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,561,220 - 56,654,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXW11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12374,015,964 - 74,154,285 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2374,015,964 - 74,154,062 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660344,473,459 - 4,624,970 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: XM_021239596   ⟹   XP_021095255
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473317,985,546 - 18,121,398 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021095255 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015185
GenBank Protein JAO01768 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021095255   ⟸   XM_021239596


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010874 ENTREZGENE
Ensembl Transcript ENSHGLT00000015340 ENTREZGENE
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  6.10.250.1840 UniProtKB/TrEMBL
InterPro Beta-TrCP_D UniProtKB/TrEMBL
  F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Fbxw11 ENTREZGENE
PANTHER F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-B UniProtKB/TrEMBL
  WD40 REPEAT PF20 UniProtKB/TrEMBL
Pfam Beta-TrCP_D UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART Beta-TrCP_D UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A0P6JE73_HETGA UniProtKB/TrEMBL