| 1342767 | ESRRB | estrogen related receptor beta | This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. [provided by RefSeq, Jul 2008] | 14 | 76310777 | 76501837 | Human | 178 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1359557 | Esrrb | estrogen-related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN positive regulation of glycogen biosynthetic process; positive regulation of glycolytic process; cell dedifferentiation (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; ammonium chloride | 6 | 111738662 | 111894087 | Rat | 171 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1621573 | Esrrb | estrogen related receptor, beta | Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II complex binding activity. Involved in several processes, including morula formation; photo receptor cell maintenance; and regulation of macromolecule biosynthetic process. Acts upstream of or within embryonic placenta development; trophectodermal cell proliferation; and trophectodermal cellular morphogenesis. Located in condensed chromosome; cytoplasm; and nucleus. Part of integrator complex. Is expressed in several structures, including central nervous system; early conceptus; endocrine gland; gonad; and sensory organ. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Orthologous to human ESRRB (estrogen related receptor beta). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 86407891 | 86568402 | Mouse | 192 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8866145 | Esrrb | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cell dedifferentiation (ortholog); cell population pr oliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | NW_004955438 | 365375 | 534086 | Chinchilla | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11878262 | ESRRB | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell dedifferentiation (o rtholog); cell population proliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | 14 | 56868361 | 57060552 | Bonobo | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12433108 | ESRRB | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell dedifferentiation (o rtholog); cell population proliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | 8 | 49253877 | 49424148 | Dog | 81 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12724245 | Esrrb | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell dedifferentiation (o rtholog); cell population proliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | NW_004936488 | 5350133 | 5452366 | Squirrel | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18923913 | Esrrb | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell dedifferentiation (o rtholog); cell population proliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | | | | Naked Mole-Rat | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240231 | esrrb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 20866816 | ESRRB | estrogen related receptor beta | | | | | Green Monkey | | symbol | gene, protein-coding |
| 14025802 | ESRRB | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell dedifferentiation (o rtholog); cell population proliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | | | | Pig | 81 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626034798 | Esrrb | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN cell dedifferentiation (ortholog); cell population pr oliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | | | | Black Rat | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18507354 | ESRRB | estrogen related receptor beta | ENCODES a protein that exhibits cis-regulatory region sequence-specific DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cell dedifferentiation (o rtholog); cell population proliferation (ortholog); embryonic placenta development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 35 (ortholog); dilated cardiomyopathy (ortholog); FOUND IN condensed chromosome (ortholog); cytoplasm (ortholog); integrator complex (ortholog) | | | | Green Monkey | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240230 | esrrb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1582974 | Esrrb-ps1 | estrogen-related receptor beta, pseudogene 1 | | X | 144544971 | 144546096 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1305947 | Ift57 | intraflagellar transport 57 | INVOLVED IN apoptotic process (ortholog); heart looping (ortholog); left/right pattern formation (ortholog); PARTICIPATES IN Huntington's disease pathway; ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); Huntington's disease (ortholog); orofaciodigital syndrome XVIII (ortholog); FOUND IN axoneme (o rtholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A | 11 | 64528349 | 64593545 | Rat | 117 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314279 | IFT57 | intraflagellar transport 57 | Predicted to enable DNA binding activity. Acts upstream of or within apoptotic process and regulation of apoptotic process. Located in ciliary base and photoreceptor connecting cilium. Part of intraciliary transport particle B. Implicated in orofaciodigital syndrome XVIII. [provided by Alliance of G enome Resources, Jul 2025] | 3 | 108160812 | 108222424 | Human | 152 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1314280 | Ift57 | intraflagellar transport 57 | Predicted to enable DNA binding activity. Acts upstream of or within several processes, including cilium assembly; epithelial tube morphogenesis; and negative regulation of keratinocyte proliferation. Located in several cellular components, including cytoskeleton; dendrite terminus; and photorecepto r connecting cilium. Part of intraciliary transport particle B. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo mesoderm; limb bud; and node. Human ortholog(s) of this gene implicated in orofaciodigital syndrome XVIII. Orthologous to human IFT57 (intraflagellar transport 57). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 49519657 | 49585489 | Mouse | 141 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |