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19 records found for search term Eif4g1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1306144Eif4g1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits eukaryotic initiation factor 4E binding; ATP binding (ortholog); mRNA binding (ortholog); INVOLVED IN lung development; response to ethanol; behavioral fear response (ortholog); PARTICIPATES IN translation initiation pathway; myocarditis pathway; RNA transport pathway119372632293746387Rat216symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1314591EIF4G1eukaryotic translation initiation factor 4 gamma 1The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwindin3184314606184335358Human311symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1550408Eif4g1eukaryotic translation initiation factor 4, gamma 1This gene encodes a member of the eukaryotic translation initiation factors (eIF) that play important roles in translation initiation by mediating recruitment of additional initiation factors and providing a scaffold for ribosome/mRNA-bridging. Along with eIF4A and eIF4E, the encoded protein forms t162049145720511633Mouse274symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8974936Eif4g1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits ATP binding (ortholog); eukaryotic initiation factor 4E binding (ortholog); mRNA binding (ortholog); INVOLVED IN behavioral fear response (ortholog); cellular response to nutrient levels (ortholog); energy homeostasis (ortholog); PARTICIPATES IN translation initiationNW_0049554202316154123179788Chinchilla75symbolgene, protein-coding, MODEL [RefSeq]
11756718EIF4G1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits eukaryotic initiation factor 4E binding (ortholog); INVOLVED IN behavioral fear response (ortholog); lung development (ortholog); positive regulation of neuron differentiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH autistic disorde3181351938181372776Bonobo81symbolgene, protein-coding, MODEL [RefSeq]
12261666EIF4G1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits eukaryotic initiation factor 4E binding (ortholog); INVOLVED IN behavioral fear response (ortholog); lung development (ortholog); positive regulation of neuron differentiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH autistic disorde341719458817214498Dog80symbolgene, protein-coding, MODEL [RefSeq]
12616390Eif4g1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits eukaryotic initiation factor 4E binding (ortholog); INVOLVED IN behavioral fear response (ortholog); lung development (ortholog); positive regulation of neuron differentiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH autistic disordeNW_00493657855485265567220Squirrel81symbolgene, protein-coding, MODEL [RefSeq]
14383330eIF4G1Flysymbolgene, null
18909986Eif4g1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits ATP binding (ortholog); eukaryotic initiation factor 4E binding (ortholog); translation factor activity, RNA binding (ortholog); INVOLVED IN behavioral fear response (ortholog); cellular response to nutrient levels (ortholog); energy homeostasis (ortholog); PARTICIPATNaked Mole-Rat78symbolgene, protein-coding, MODEL [RefSeq]
626162793Eif4g1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits ATP binding (ortholog); eukaryotic initiation factor 4E binding (ortholog); mRNA binding (ortholog); INVOLVED IN behavioral fear response (ortholog); cellular response to nutrient levels (ortholog); energy homeostasis (ortholog); PARTICIPATES IN translation initiationBlack Rat75symbolgene, protein-coding, MODEL [RefSeq]
13992400EIF4G1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits eukaryotic initiation factor 4E binding (ortholog); INVOLVED IN behavioral fear response (ortholog); lung development (ortholog); positive regulation of neuron differentiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH autistic disordePig83symbolgene, protein-coding, PROVISIONAL [RefSeq]
18395032EIF4G1eukaryotic translation initiation factor 4 gamma 1ENCODES a protein that exhibits eukaryotic initiation factor 4E binding (ortholog); INVOLVED IN behavioral fear response (ortholog); lung development (ortholog); positive regulation of neuron differentiation (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH autistic disordeGreen Monkey81symbolgene, protein-coding, MODEL [RefSeq]
155243135eif4g1Tropical Clawed Frogsymbolgene, null
155246277eif4g1.LAfrican Clawed Frogsymbolgene, null
155243136eif4g1.SAfrican Clawed Frogsymbolgene, null
1583489Eif4g1-ps1eukaryotic translation initiation factor 4 gamma 1, pseudogene 1ENCODES a pseudogene that exhibits RNA binding (inferred); translation initiation factor activity (inferred); INVOLVED IN regulation of translation (inferred); translation (inferred); translational initiation (inferred)2104621297104626543Rat5symbol , PhenoGengene, pseudo, MODEL [RefSeq]
1592929Eif4g1-ps2eukaryotic translation initiation factor 4 gamma 1, pseudogene 2981841068188548Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
1587188Eif4g1-ps3eukaryotic translation initiation factor 4 gamma 1, pseudogene 349692000896922336Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
1605487PAIP2Bpoly(A) binding protein interacting protein 2BMost mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Va27118273871227103Human68descriptiongene, protein-coding, VALIDATED [RefSeq]