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17 records found for search term Edem1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1349759EDEM1ER degradation enhancing alpha-mannosidase like protein 1Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol; protein targeting to ER; and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic351877075219958Human154symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1557813Edem1ER degradation enhancer, mannosidase alpha-like 1Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in positive regulation of retrograde protein transport, ER to cytosol and trimming of terminal mannose on C branch. Acts upstream of or within ERAD pathway. Located in endoplasmic reticulum membrane. Is expressed in embryo and6108800984108836317Mouse162symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1563633Edem1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); misfolded protein binding (ortholog); INVOLVED IN endoplasmic reticulum mannose trimming (ortholog); ERAD pathway (ortholog); positive regulation of retrograde protein transport, ER to cytosol (orthol4143350989143385693Rat155symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8718979Edem1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); misfolded protein binding (ortholog); INVOLVED IN endoplasmic reticulum mannose trimming (ortholog); ERAD pathway (ortholog); positive regulation of retrograde protein transport, ER to cytosol (ortholNW_00495542181966318225561Chinchilla25symbolgene, protein-coding, MODEL [RefSeq]
11786163EDEM1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Zika fever (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane351339275162485Bonobo32symbolgene, protein-coding, MODEL [RefSeq]
12086593EDEM1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Zika fever (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane201244401312473188Dog33symbolgene, protein-coding, MODEL [RefSeq]
12648781Edem1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Zika fever (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membraneNW_00493657744866174516379Squirrel32symbolgene, protein-coding, MODEL [RefSeq]
625966093Edem1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); misfolded protein binding (ortholog); INVOLVED IN endoplasmic reticulum mannose trimming (ortholog); ERAD pathway (ortholog); positive regulation of retrograde protein transport, ER to cytosol (ortholBlack Rat25symbolgene, protein-coding, MODEL [RefSeq]
14176646EDEM1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Zika fever (ortholog); FOUND IN cytolytic granule membrane (inferred); early endosome membrane (Pig45symbolgene, protein-coding, MODEL [RefSeq]
18518975EDEM1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Zika fever (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membraneGreen Monkey32symbolgene, protein-coding, MODEL [RefSeq]
18933320Edem1ER degradation enhancing alpha-mannosidase like protein 1ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); misfolded protein binding (ortholog); INVOLVED IN ERAD pathway (ortholog); protein targeting to ER (ortholog); ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH Chemical and DrNaked Mole-Rat28symbolgene, protein-coding, MODEL [RefSeq]
14378472Edem1Flysymbolgene, null
155245449edem1Tropical Clawed Frogsymbolgene, null
155245448edem1.LAfrican Clawed Frogsymbolgene, null
155255093edem1.SAfrican Clawed Frogsymbolgene, null
16564985AC026202.3novel transcript, antisense to EDEM1Humannamegene, lncrna
16554121AC130464.1ER degradation enhancer, mannosidase alpha-like 1 (EDEM1) pseudogeneHumannamegene, unprocessed_pseudogene