| 1304956 | Ebf3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 201426446 | 201544444 | Rat | 106 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312697 | Ebf3 | early B cell factor 3 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; limb; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in hypotonia, ataxia, and delayed development syndrome. Orthologous to human EBF3 (EBF transcription factor 3). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 136795400 | 136924528 | Mouse | 109 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1346410 | EBF3 | EBF transcription factor 3 | This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulati on of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011] | 10 | 129835233 | 129964274 | Human | 321 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8786543 | Ebf3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog) | NW_004955477 | 7435324 | 7557212 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11748061 | EBF3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog) | 10 | 126432326 | 126561328 | Bonobo | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12130594 | EBF3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Ataxia (orthol og); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH digoxin; Doramectin; ivermectin | 28 | 38489635 | 38601800 | Dog | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12693240 | Ebf3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Ataxia (orthol og); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (inferred) | NW_004936486 | 16978048 | 17092209 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18413894 | EBF3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14262810 | EBF3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Ataxia (orthol og); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH zearalenone | | | | Pig | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626132614 | Ebf3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921895 | Ebf3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of DNA-templated transcription (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); ASSOCIATED WITH Ataxia (ortholog); autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155248514 | ebf3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 20866044 | EBF3 | EBF transcription factor 3 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of transcription by RNA polymeras e II (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred) | | | | Green Monkey | 11 | symbol | gene, protein-coding |
| 155244917 | ebf3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155248513 | ebf3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38622999 | EBF3-AS1 | EBF3 antisense RNA 1 | | 10 | 129857129 | 129867145 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1615690 | Ebf4 | early B cell factor 4 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-templated transcription. Predicted to be located in chromatin. Is expressed in several structures, including diaphragm; genitourinary system; nervous system; retina; and skeletal muscle. Orthologous to human EBF4 (EBF family member 4). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 130134832 | 130212402 | Mouse | 67 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1343455 | MAPRE3 | microtubule associated protein RP/EB family member 3 | The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008] | 2 | 26970637 | 27027219 | Human | 151 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1359297 | Mapre3 | microtubule-associated protein, RP/EB family, member 3 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); microtubule plus-end binding (ortholog); INVOLVED IN behavioral response to cocaine; positive regulation of dendritic spine morphogenesis; positive regulation of DNA-templated transcription (ortholo g); ASSOCIATED WITH polycystic ovary syndrome (ortholog); Spontaneous Abortions (ortholog); FOUND IN neuron to neuron synapse; cytoplasm (ortholog); cytoplasmic microtubule (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 6 | 31233736 | 31278626 | Rat | 144 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1552116 | Mapre3 | microtubule-associated protein, RP/EB family, member 3 | Enables microtubule plus-end binding activity. Involved in positive regulation of DNA-templated transcription and positive regulation of cyclin-dependent protein serine/threonine kinase activity. Located in cytoplasm; microtubule plus-end; and midbody. Colocalizes with microtubule. Orthologous to hu man MAPRE3 (microtubule associated protein RP/EB family member 3). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 30972075 | 31023447 | Mouse | 142 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16567413 | AL354950.1 | novel transcript, antisense to EBF3 | | | | | Human | | name | gene, lncrna |
| 16567516 | AL354950.2 | novel transcript, antisense to EBF3 | | | | | Human | | name | gene, lncrna |
| 16573065 | AL354950.3 | novel transcript, antisense to EBF3 | | | | | Human | | name | gene, lncrna |