| 620763 | Ccn1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (ortholog); integrin binding (ortholog); INVOLVED IN cell adhesion; cellular response to angiotensin; cellular response to hypoxia; ASSOCIATED WITH Experimental Arthritis; intracranial aneurysm; Acute Coronary Syndrome (ortholog); FOUND IN cytosol; membrane; INTERACTS WITH 1,2,4-trimethylbenzene; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate | 2 | 237222730 | 237225689 | Rat | 507 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 731720 | CCN1 | cellular communication network factor 1 | The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apopto sis, and extracellular matrix formation. [provided by RefSeq, Sep 2011] | 1 | 85580761 | 85583950 | Human | 499 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 731721 | Ccn1 | cellular communication network factor 1 | Enables extracellular matrix binding activity and integrin binding activity. Acts upstream of or within several processes, including chondroblast differentiation; circulatory system development; and regulation of apoptotic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including brain; embryo mesenchyme; extraembryonic component; heart; and sensory organ. Used to study atrial heart septal defect 1 and atrioventricular septal defect. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human CCN1 (cellular communication network factor 1). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 145352726 | 145355740 | Mouse | 540 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8889311 | Ccn1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (ortholog); integrin binding (ortholog); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); ASSOCIATED WITH Acute Coronary Synd rome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog) | NW_004955423 | 8416498 | 8419029 | Chinchilla | 77 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11724776 | CCN1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (inferred); growth factor binding (inferred); heparin binding (inferred); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); AS SOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog) | 1 | 118138739 | 118141681 | Bonobo | 94 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12214779 | CCN1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (ortholog); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog) | 6 | 62443285 | 62446246 | Dog | 93 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12441473 | Ccn1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (inferred); growth factor binding (inferred); heparin binding (inferred); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); AS SOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog) | NW_004936608 | 152174 | 155123 | Squirrel | 94 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18462453 | CCN1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (inferred); growth factor binding (inferred); heparin binding (inferred); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); AS SOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog) | | | | Green Monkey | 94 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 14035151 | CCN1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (inferred); growth factor binding (inferred); integrin binding (inferred); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); A SSOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); INTERACTS WITH bis(2-chloroethyl) sulfide; deoxynivalenol | | | | Pig | 96 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919884 | Ccn1 | cellular communication network factor 1 | ENCODES a protein that exhibits extracellular matrix binding (ortholog); INVOLVED IN apoptotic process involved in heart morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrioventricular valve morphogenesis (ortholog); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); Acute Heart Injury (ortholog); acute myocardial infarction (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog) | | | | Naked Mole-Rat | 92 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |