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52 records found for search term Cyb561
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1310987Cyb561cytochrome b-561ENCODES a protein that exhibits transmembrane monodehydroascorbate reductase activity (ortholog); INVOLVED IN ascorbate homeostasis (ortholog); intracellular iron ion homeostasis (ortholog); ASSOCIATED WITH Orthostatic Hypotension 2 (ortholog); FOUND IN chromaffin granule membrane (ortholog); INTERA109137786691388548Rat111symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1322199CYB561cytochrome b561Predicted to enable transmembrane monodehydroascorbate reductase activity. Predicted to be involved in ascorbate homeostasis. Predicted to be located in chromaffin granule membrane. Predicted to be active in lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]176343230463446639Human130symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1322200Cyb561cytochrome b-561Enables transmembrane monodehydroascorbate reductase activity. Involved in ascorbate homeostasis and intracellular iron ion homeostasis. Located in chromaffin granule membrane. Is expressed in several structures, including genitourinary system; gut; nervous system; node; and nose. Orthologous to hum11105824528105844157Mouse153symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
12371766CYB561cytochrome b561ENCODES a protein that exhibits transmembrane monodehydroascorbate reductase activity (ortholog); INVOLVED IN ascorbate homeostasis (ortholog); intracellular iron ion homeostasis (ortholog); ASSOCIATED WITH Orthostatic Hypotension 2 (ortholog); FOUND IN chromaffin granule membrane (inferred); cytopl91146173811474413Dog13symbolgene, protein-coding, MODEL [RefSeq]
13916843CYB561cytochrome b561ENCODES a protein that exhibits transmembrane monodehydroascorbate reductase activity (ortholog); INVOLVED IN ascorbate homeostasis (ortholog); ASSOCIATED WITH Orthostatic Hypotension 2 (ortholog); FOUND IN chromaffin granule membrane (ortholog); INTERACTS WITH deoxynivalenol; resveratrolPig19symbol , old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
18734032CYB561cytochrome b561ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN ascorbate homeostasis (inferred); intracellular iron ion homeostasis (inferred); ASSOCIATED WITH Orthostatic Hypotension 2 (Green Monkey14symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155249831cyb561Tropical Clawed Frogsymbolgene, null
155253826cyb561.LAfrican Clawed Frogsymbolgene, null
405859308cyb561.SAfrican Clawed Frogsymbolgene, null
405860035cyb561.SAfrican Clawed Frogsymbolgene, null
405862119cyb561.SAfrican Clawed Frogsymbolgene, null
405863076cyb561.SAfrican Clawed Frogsymbolgene, null
626469029cyb561.SAfrican Clawed Frogsymbolgene, null
11976754LOC100993774transmembrane ascorbate-dependent reductase CYB561ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN ascorbate homeostasis (inferred); intracellular iron ion homeostasis (inferred); ASSOCIATED WITH Orthostatic Hypotension 2 (175751382057528326Bonobo14ensembl_gene_symbol , namegene, protein-coding, MODEL [RefSeq]
1304670Cyb561a3cytochrome b561 family, member A3ENCODES a protein that exhibits transmembrane ascorbate ferrireductase activity (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); FOUND IN late endosome membrane (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH 2,4-dinitrotoluene; aflatoxin B1; alph1216641108216662495Rat85symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1350964CYB561A3cytochrome b561 family member A3Predicted to enable transmembrane ascorbate ferrireductase activity. Predicted to be involved in intracellular iron ion homeostasis. Located in nucleolus. [provided by Alliance of Genome Resources, Jul 2025]116134874561362283Human83symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1615697Cyb561a3cytochrome b561 family, member A3Enables transmembrane ascorbate ferrireductase activity. Involved in intracellular iron ion homeostasis. Located in late endosome membrane and lysosomal membrane. Is expressed in ganglia; jaw bone; and neural retina. Orthologous to human CYB561A3 (cytochrome b56191055452110574196Mouse84symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
12280480CYB561A3cytochrome b561 family member A3ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity (inferred); transmembrane ascorbate ferrireductase activity (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); transmembrane transport (inferred); FOUND IN late endosome membrane (inferred); lys185503978855049739Dog16symbolgene, protein-coding, MODEL [RefSeq]
13967666CYB561A3cytochrome b561 family member A3ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity (inferred); transmembrane ascorbate ferrireductase activity (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); transmembrane transport (inferred); FOUND IN late endosome membrane (inferred); lysPig16symbolgene, protein-coding, MODEL [RefSeq]
18443008CYB561A3cytochrome b561 family member A3ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity (inferred); transmembrane ascorbate ferrireductase activity (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); transmembrane transport (inferred); FOUND IN late endosome membrane (inferred); lysGreen Monkey16symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
1310829Cyb561d1cytochrome b561 family, member D1ENCODES a protein that exhibits metal ion binding (inferred); transmembrane ascorbate ferrireductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred); INTERACTS WITH 2,2',4,4'-Tetrabrom2198523031198525671Rat59symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1321956CYB561D1cytochrome b561 family member D1Predicted to enable metal ion binding activity; transmembrane ascorbate ferrireductase activity; and transmembrane monodehydroascorbate reductase activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]1109494094109500435Human62symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1619986Cyb561d1cytochrome b-561 domain containing 1Predicted to enable metal ion binding activity; transmembrane ascorbate ferrireductase activity; and transmembrane monodehydroascorbate reductase activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Orthologous to human CYB5613108103082108109542Mouse63symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
12101228CYB561D1cytochrome b561 family member D1ENCODES a protein that exhibits metal ion binding (inferred); transmembrane ascorbate ferrireductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred)64236302842365574Dog9symbolgene, protein-coding, MODEL [RefSeq]
14035727CYB561D1cytochrome b561 family member D1ENCODES a protein that exhibits metal ion binding (inferred); transmembrane ascorbate ferrireductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred)Pig9symbolgene, protein-coding, MODEL [RefSeq]
18544453CYB561D1cytochrome b561 family member D1ENCODES a protein that exhibits metal ion binding (inferred); transmembrane ascorbate ferrireductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred)Green Monkey7symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
598151031cyb561d1Tropical Clawed Frogsymbolgene, null
598151066cyb561d1Tropical Clawed Frogsymbolgene, null
598151697cyb561d1Tropical Clawed Frogsymbolgene, null
1353992CYB561D2cytochrome b561 family member D235036536350368197Humansymbol , old_gene_name , COSMIC , Human Proteome Mapgene, ncrna, VALIDATED [RefSeq]
1359644Cyb561d2cytochrome b561 family, member D2ENCODES a protein that exhibits heme binding (ortholog); transmembrane ascorbate ferrireductase activity (ortholog); transmembrane monodehydroascorbate reductase activity (ortholog); INVOLVED IN ascorbate homeostasis (ortholog); FOUND IN endoplasmic reticulum (ortholog); vesicle (ortholog); INTERACT8117091844117094434Rat94symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1552368Cyb561d2cytochrome b-561 domain containing 2Enables heme binding activity and transmembrane ascorbate ferrireductase activity. Predicted to be involved in ascorbate homeostasis. Located in endoplasmic reticulum and vesicle. Is expressed in several structures, including Meckel's cartilage; female reproductive system; lower leg mesenchyme; skel9107416210107419392Mouse90symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
12160767CYB561D2cytochrome b561 family member D2ENCODES a protein that exhibits heme binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN ascorbate homeostasis (inferred); transmembrane transport (inferred); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic r203900294139007085Dog19symbolgene, protein-coding, MODEL [RefSeq]
18540456CYB561D2cytochrome b561 family member D2ENCODES a protein that exhibits heme binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN ascorbate homeostasis (inferred); transmembrane transport (inferred); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic rGreen Monkey16symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
155239688cyb561d2Tropical Clawed Frogsymbolgene, null
155782982CYB561D2cytochrome b561 family member D2Enables heme binding activity and transmembrane monodehydroascorbate reductase activity. Involved in ascorbate homeostasis. Predicted to be located in vesicle. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]35035086250354069Human84symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
626468260cyb561d1.SAfrican Clawed Frogsymbolgene, null
626469206cyb561d1.SAfrican Clawed Frogsymbolgene, null
155259088cyb561d2.LAfrican Clawed Frogsymbolgene, null
155253416cyb561d2.SAfrican Clawed Frogsymbolgene, null
1313951CYBRD1cytochrome b reductase 1This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]2171522233171558129Human144old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
18925399LOC101704367cytochrome b561 domain-containing protein 2ENCODES a protein that exhibits heme binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic reticulum (inferred)Naked Mole-Rat10old_gene_symbolgene, protein-coding, MODEL [RefSeq]
14054868LOC100517372cytochrome b561 domain-containing protein 2ENCODES a protein that exhibits heme binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN ascorbate homeostasis (inferred); transmembrane transport (inferred); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic rPig20ensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
11939240LOC100970458probable transmembrane reductase CYB561D1ENCODES a protein that exhibits metal ion binding (inferred); transmembrane ascorbate ferrireductase activity (inferred); transmembrane monodehydroascorbate reductase activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred)1111870272111877783Bonobo7ensembl_gene_symbol , namegene, protein-coding, MODEL [RefSeq]
11813109LOC100972845transmembrane reductase CYB561D2ENCODES a protein that exhibits heme binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN ascorbate homeostasis (inferred); transmembrane transport (inferred); FOUND IN cytoplasmic vesicle (inferred); cytoplasmic vesicle membrane (inferred); endoplasmic r35027698550280196Bonobo16ensembl_gene_symbol , namegene, protein-coding, MODEL [RefSeq]
11993614LOC100974743lysosomal membrane ascorbate-dependent ferrireductase CYB561A3ENCODES a protein that exhibits metal ion binding (inferred); oxidoreductase activity (inferred); transmembrane ascorbate ferrireductase activity (inferred); INVOLVED IN intracellular iron ion homeostasis (inferred); transmembrane transport (inferred); FOUND IN endomembrane system (inferred); late e115664832256661758Bonobo17ensembl_gene_symbol , namegene, protein-coding, MODEL [RefSeq]
8737909LOC102004854cytochrome b561 domain-containing protein 2NW_00495553221407452155258Chinchillaensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
8782229LOC102016503cytochrome b ascorbate-dependent protein 3ENCODES a protein that exhibits transmembrane ascorbate ferrireductase activity (ortholog); INVOLVED IN intracellular iron ion homeostasis (ortholog); FOUND IN late endosome membrane (ortholog); lysosomal membrane (ortholog); lysosome (ortholog)NW_00495551161916446200099Chinchilla7ensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
8993911LOC102030342cytochrome b561 domain-containing protein 1NW_0049554351291345212918976Chinchilla2ensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
155782919LOC127898564CYB561D2-LOC10192896535035086250368197Humannamegene, ncrna, VALIDATED [RefSeq]
1604148FRRS1ferric chelate reductase 1Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]19970397099766635Human63descriptiongene, protein-coding, VALIDATED [RefSeq]
11683406LOC100972759plasma membrane ascorbate-dependent reductase CYBRD1ENCODES a protein that exhibits identical protein binding (inferred); metal ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN response to iron ion (ortholog); PARTICIPATES IN iron uptake pathway; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN apical plasma membrane (inferred); b2B5881355458849162Bonobo25old_gene_namegene, protein-coding, MODEL [RefSeq]