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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cyb561d2 | Rat | (+)-catechin | multiple interactions | ISO | CYB561D2 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CYB561D2 mRNA | CTD | PMID:24763279 | Cyb561d2 | Rat | (-)-alpha-phellandrene | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of CYB561D2 mRNA | CTD | PMID:25075043 | Cyb561d2 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | CYB561D2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CYB561D2 mRNA | CTD | PMID:22079256 | Cyb561d2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Cyb561d2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYB561D2 mRNA | CTD | PMID:22206623 | Cyb561d2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Cyb561d2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYB561D2 mRNA | CTD | PMID:17942748 | Cyb561d2 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Cyb561d2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Cyb561d2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CYB561D2 mRNA | CTD | PMID:17942748 | Cyb561d2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CYB561D2 mRNA | CTD | PMID:21570461 | Cyb561d2 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of CYB561D2 mRNA | CTD | PMID:28973697 | Cyb561d2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CYB561D2 mRNA | CTD | PMID:30047161 | Cyb561d2 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CYB561D2 mRNA | CTD | PMID:28959563 | Cyb561d2 | Rat | aflatoxin B1 | increases methylation | ISO | CYB561D2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CYB561D2 gene | CTD | PMID:28458013 | Cyb561d2 | Rat | alpha-phellandrene | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of CYB561D2 mRNA | CTD | PMID:25075043 | Cyb561d2 | Rat | antirheumatic drug | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of CYB561D2 mRNA | CTD | PMID:24449571 | Cyb561d2 | Rat | aristolochic acid A | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of CYB561D2 mRNA | CTD | PMID:33212167 | Cyb561d2 | Rat | atrazine | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of CYB561D2 mRNA | CTD | PMID:22378314 | Cyb561d2 | Rat | benzo[a]pyrene | multiple interactions | ISO | Cyb561d2 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to CYB561D2 promoter] | CTD | PMID:19654925 | Cyb561d2 | Rat | benzo[a]pyrene | increases methylation | ISO | CYB561D2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CYB561D2 3' UTR | CTD | PMID:27901495 | Cyb561d2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CYB561D2 mRNA | CTD | PMID:25181051 | Cyb561d2 | Rat | bisphenol A | decreases methylation | ISO | Cyb561d2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of CYB561D2 promoter | CTD | PMID:27312807 | Cyb561d2 | Rat | cadmium atom | increases expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | Cadmium results in increased expression of CYB561D2 mRNA | CTD | PMID:26187450 | Cyb561d2 | Rat | cadmium dichloride | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of CYB561D2 mRNA | CTD | PMID:38382870 | Cyb561d2 | Rat | calcitriol | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of CYB561D2 mRNA | CTD | PMID:21592394 | Cyb561d2 | Rat | calcitriol | multiple interactions | ISO | CYB561D2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of CYB561D2 mRNA | CTD | PMID:21592394 | Cyb561d2 | Rat | chlorpyrifos | increases expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of CYB561D2 mRNA | CTD | PMID:37019170 | Cyb561d2 | Rat | cisplatin | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of CYB561D2 mRNA | CTD | PMID:27392435 | Cyb561d2 | Rat | copper(II) sulfate | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of CYB561D2 mRNA | CTD | PMID:19549813 | Cyb561d2 | Rat | cyclosporin A | decreases methylation | ISO | CYB561D2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of CYB561D2 promoter | CTD | PMID:27989131 | Cyb561d2 | Rat | Dibutyl phosphate | affects expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of CYB561D2 mRNA | CTD | PMID:37042841 | Cyb561d2 | Rat | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of CYB561D2 mRNA | CTD | PMID:21658437 | Cyb561d2 | Rat | elemental selenium | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Selenium results in increased expression of CYB561D2 mRNA | CTD | PMID:19244175 | Cyb561d2 | Rat | epoxiconazole | decreases expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of CYB561D2 mRNA | CTD | PMID:35436446 | Cyb561d2 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of CYB561D2 mRNA | CTD | PMID:24136188 | Cyb561d2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of CYB561D2 mRNA | CTD | PMID:24136188 | Cyb561d2 | Rat | folic acid | multiple interactions | ISO | Cyb561d2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CYB561D2 mRNA | CTD | PMID:22206623 | Cyb561d2 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of CYB561D2 mRNA | CTD | PMID:33387578 | Cyb561d2 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of CYB561D2 mRNA | CTD | PMID:30047161 | Cyb561d2 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Methylnitronitrosoguanidine results in decreased expression of CYB561D2 mRNA | CTD | PMID:12634122 | Cyb561d2 | Rat | ozone | multiple interactions | ISO | Cyb561d2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of CYB561D2 mRNA | CTD | PMID:34911549 | Cyb561d2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CYB561D2 mRNA | CTD | PMID:33387578 | Cyb561d2 | Rat | paracetamol | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CYB561D2 mRNA | CTD | PMID:22230336 | Cyb561d2 | Rat | paracetamol | affects response to substance | ISO | CYB561D2 (Homo sapiens) | 6480464 | CYB561D2 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | Cyb561d2 | Rat | phenobarbital | affects expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of CYB561D2 mRNA | CTD | PMID:19159669 | Cyb561d2 | Rat | potassium chromate | decreases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of CYB561D2 mRNA | CTD | PMID:22079256 | Cyb561d2 | Rat | potassium chromate | multiple interactions | ISO | CYB561D2 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CYB561D2 mRNA | CTD | PMID:22079256 | Cyb561d2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of CYB561D2 mRNA | CTD | PMID:30047161 | Cyb561d2 | Rat | selenium atom | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Selenium results in increased expression of CYB561D2 mRNA | CTD | PMID:19244175 | Cyb561d2 | Rat | sodium arsenite | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of CYB561D2 mRNA | CTD | PMID:38568856 | Cyb561d2 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of CYB561D2 mRNA | CTD | PMID:30047161 | Cyb561d2 | Rat | temozolomide | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of CYB561D2 mRNA | CTD | PMID:31758290 | Cyb561d2 | Rat | testosterone | increases expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of CYB561D2 mRNA | CTD | PMID:21592394 | Cyb561d2 | Rat | testosterone | multiple interactions | ISO | CYB561D2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of CYB561D2 mRNA | CTD | PMID:21592394 | Cyb561d2 | Rat | thapsigargin | decreases expression | ISO | Cyb561d2 (Mus musculus) | 6480464 | Thapsigargin results in decreased expression of CYB561D2 protein | CTD | PMID:24648495 | Cyb561d2 | Rat | triphenyl phosphate | affects expression | ISO | CYB561D2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CYB561D2 mRNA | CTD | PMID:37042841 | |