| 1306882 | Csnk2a2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cerebral cortex development; liver regeneration; spermatogenesis; PARTICIPATES IN E-cadherin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle; chromatin; nucleus (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole | 19 | 9562340 | 9602136 | Rat | 172 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1315751 | CSNK2A2 | casein kinase 2 alpha 2 | This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apopto sis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017] | 16 | 58157907 | 58198106 | Human | 195 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315752 | Csnk2a2 | casein kinase 2, alpha prime polypeptide | Enables protein serine/threonine kinase activity. Acts upstream of or within protein phosphorylation; regulation of cell cycle; and spermatogenesis. Predicted to be located in acrosomal vesicle and chromatin. Predicted to be part of PcG protein complex and protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study male infertility. Orthologous to human CSNK2A2 (casein kinase 2 alpha 2). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 96172724 | 96215505 | Mouse | 215 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8934619 | Csnk2a2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cerebral cortex development (ortholog); double-strand break repair (ortholog); liver regeneration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; mitochondri al autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog); nucleus (ortholog) | NW_004955433 | 15677788 | 15718894 | Chinchilla | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11915389 | CSNK2A2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cerebral cortex development (ortholog); liver regeneration (ortholog); obsolete positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN E-cadhe rin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog) | 16 | 38426399 | 38466575 | Bonobo | 61 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12351956 | CSNK2A2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cerebral cortex development (ortholog); double-strand break repair (ortholog); liver regeneration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; mitochondrial aut ophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog); PcG protein complex (ortholog) | 2 | 58361328 | 58441701 | Dog | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12685164 | Csnk2a2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cerebral cortex development (ortholog); liver regeneration (ortholog); obsolete positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN E-cadhe rin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog) | NW_004936475 | 10030408 | 10073576 | Squirrel | 61 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18700982 | CSNK2A2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cerebral cortex development (ortholog); liver regeneration (ortholog); obsolete positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN E-cadhe rin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog) | | | | Green Monkey | 61 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232036 | csnk2a2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18934793 | Csnk2a2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cerebral cortex development (ortholog); double-strand break repair (ortholog); liver regeneration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; mitochondrial aut ophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog); PcG protein complex (ortholog) | | | | Naked Mole-Rat | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625990188 | Csnk2a2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cerebral cortex development (ortholog); double-strand break repair (ortholog); liver regeneration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; mitochondri al autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog); nucleus (ortholog) | | | | Black Rat | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14113019 | CSNK2A2 | casein kinase 2 alpha 2 | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cerebral cortex development (ortholog); liver regeneration (ortholog); obsolete positive regulation of protein targeting to mitochondrion (ortholog); PARTICIPATES IN E-cadhe rin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH male infertility (ortholog); Oxygen-Induced Retinopathy (ortholog); Skin Neoplasms (ortholog); FOUND IN acrosomal vesicle (ortholog); chromatin (ortholog) | | | | Pig | 61 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232035 | csnk2a2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155242431 | csnk2a2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16562977 | AC009107.1 | novel transcript, antisense to CSNK2A2 | | | | | Human | | name | gene, lncrna |
| 16563005 | AC009107.2 | uncharacterized LOC101927556 | | 16 | 58128884 | 58160424 | Human | | old_gene_name | gene, ncrna, VALIDATED [RefSeq] |
| 1562102 | Csnk2a2ip | casein kinase 2 subunit alpha' interacting protein | FOUND IN nucleus (ortholog); INTERACTS WITH titanium dioxide (ortholog); triptonide (ortholog); valproic acid (ortholog) | 11 | 15574054 | 15700131 | Rat | 5 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1618989 | Csnk2a2ip | casein kinase 2, alpha prime interacting protein | Located in male germ cell nucleus. Orthologous to human CSNK2A2IP (casein kinase 2 subunit alpha' interacting protein). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 64298173 | 64422694 | Mouse | 7 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 12683464 | Csnk2a2ip | casein kinase 2 subunit alpha' interacting protein | FOUND IN nucleus (ortholog) | NW_004936610 | 1326500 | 1329145 | Squirrel | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13208907 | CSNK2A2IP | casein kinase 2 subunit alpha' interacting protein | Predicted to be located in male germ cell nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 88338456 | 88467594 | Human | 5 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 32731363 | CSNK2A2IP | casein kinase 2 subunit alpha' interacting protein | FOUND IN nucleus (ortholog) | 3 | 88483731 | 88619102 | Bonobo | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18618608 | CSNK2A2IP | casein kinase 2 subunit alpha' interacting protein | FOUND IN nucleus (ortholog) | | | | Green Monkey | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625975290 | Csnk2a2ip | casein kinase 2 subunit alpha' interacting protein | FOUND IN nucleus (ortholog) | | | | Black Rat | 2 | symbol | gene, protein-coding, MODEL [RefSeq] |