| 1351351 | CSF2RA | colony stimulating factor 2 receptor subunit alpha | The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008] | X | 1268814 | 1325218 | Human | 162 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1351351 | CSF2RA | colony stimulating factor 2 receptor subunit alpha | The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008] | Y | 1268814 | 1325218 | Human | 162 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1594330 | Csf2ra | colony stimulating factor 2 receptor subunit alpha | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); granulocyte colony-stimulating factor receptor activity (ortholog); INVOLVED IN response to ethanol; cell surface receptor signaling pathway via JAK-STAT (ortholog); cellular response to granulocyte macrophage colony-stimulating factor stimulus (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH pulmonary alveolar proteinosis (ortholog); Pulmonary Surfactant Metabolism Dysfunction 4 (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 14 | 113219 | 118808 | Rat | 111 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1614464 | Csf2ra | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | Predicted to enable cytokine receptor activity. Predicted to be involved in cell surface receptor signaling pathway via JAK-STAT; granulocyte-macrophage colony-stimulating factor signaling pathway; and positive regulation of leukocyte proliferation. Predicted to be located in membrane. Predicted to be part of granulocyte macrophage colony-stimulating factor receptor complex. Is expressed in early conceptus; female reproductive system; and liver. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human CSF2RA (colony stimulating factor 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 61205629 | 61221141 | Mouse | 116 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 12304352 | CSF2RA | colony stimulating factor 2 receptor subunit alpha | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); granulocyte colony-stimulating factor receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); cellular response to granulocyte macrophage colony-stimulating fa ctor stimulus (ortholog); granulocyte-macrophage colony-stimulating factor signaling pathway (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH pulmonary alveolar proteinosis (ortholog); Pulmonary Surfactant Metabolism Dysfunction 4 (ortholog); FOUND IN plasma membrane (ortholog) | X | 832170 | 855548 | Dog | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18899926 | Csf2ra | colony stimulating factor 2 receptor subunit alpha | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); granulocyte colony-stimulating factor receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); cellular response to granulocyte macrophage colony-stimulating fa ctor stimulus (ortholog); granulocyte-macrophage colony-stimulating factor signaling pathway (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH pulmonary alveolar proteinosis (ortholog); Pulmonary Surfactant Metabolism Dysfunction 4 (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14131904 | CSF2RA | colony stimulating factor 2 receptor subunit alpha | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); granulocyte colony-stimulating factor receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); cellular response to granulocyte macrophage colony-stimulating fa ctor stimulus (ortholog); granulocyte-macrophage colony-stimulating factor signaling pathway (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH pulmonary alveolar proteinosis (ortholog); Pulmonary Surfactant Metabolism Dysfunction 4 (ortholog); FOUND IN plasma membrane (ortholog) | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18672777 | CSF2RA | colony stimulating factor 2 receptor subunit alpha | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); granulocyte colony-stimulating factor receptor activity (ortholog); INVOLVED IN cellular response to granulocyte macrophage colony-stimulating factor stimulus (ortholog); response to ethanol (ortholog); PARTICI PATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH pulmonary alveolar proteinosis (ortholog); Pulmonary Surfactant Metabolism Dysfunction 4 (ortholog); FOUND IN plasma membrane (ortholog) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12499845 | LOC101965277 | colony stimulating factor 2 receptor subunit alpha | ENCODES a protein that exhibits granulocyte colony-stimulating factor binding (ortholog); granulocyte colony-stimulating factor receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); cellular response to granulocyte macrophage colony-stimulating fa ctor stimulus (ortholog); granulocyte-macrophage colony-stimulating factor signaling pathway (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH pulmonary alveolar proteinosis (ortholog); Pulmonary Surfactant Metabolism Dysfunction 4 (ortholog); FOUND IN plasma membrane (ortholog) | NW_004936644 | 3835462 | 3842471 | Squirrel | 14 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8906269 | LOC102006686 | granulocyte-macrophage colony-stimulating factor receptor subunit alpha | | NW_004955499 | 987241 | 1000290 | Chinchilla | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1348134 | IL3RA | interleukin 3 receptor subunit alpha | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), a nd interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] | X | 1336785 | 1382689 | Human | 102 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1348134 | IL3RA | interleukin 3 receptor subunit alpha | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), a nd interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] | Y | 1336785 | 1382689 | Human | 102 | description | gene, protein-coding, REVIEWED [RefSeq] |