Clec4g Gene Search Result

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13 records found for search term Clec4g

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1354383	CLEC4G	C-type lectin domain family 4 member G	This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as we ... (more) ll as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020]	19	7728957	7732110	Human	61	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1557774	Clec4g	C-type lectin domain family 4, member g	Enables polysaccharide binding activity. Acts upstream of or within negative regulation of T cell mediated immunity; negative regulation of alpha-beta T cell proliferation; and negative regulation of immature T cell proliferation in thymus. Located in plasma membrane. Orthologous to human CLEC4G ... (more) e='font-weight:700;'>CLEC4G (C-type lectin domain family 4 member G). [provided by Alliance of Genome Resources, Jul 2025]	8	3757066	3770695	Mouse	76	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1597482	Clec4g	C-type lectin domain family 4, member G	ENCODES a protein that exhibits carbohydrate derivative binding (ortholog); D-mannose binding (ortholog); fructose binding (ortholog); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); positive regulation of viral life cyc ... (more) le (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH bisphenol A; indole-3-methanol; paraquat	12	6578266	6582913	Rat	62	symbol , PhenoGen	gene, protein-coding, MODEL [RefSeq]
8762449	Clec4g	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate derivative binding (ortholog); D-mannose binding (ortholog); fructose binding (ortholog); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); positive regulation of viral life cyc ... (more) le (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN plasma membrane (ortholog)	NW_004955563	1571374	1574901	Chinchilla	19	symbol	gene, protein-coding, MODEL [RefSeq]
11804928	CLEC4G	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate binding (inferred); carbohydrate derivative binding (inferred); D-mannose binding (inferred); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH hepatocellular ca ... (more) rcinoma (ortholog); FOUND IN plasma membrane (inferred)	19	7015848	7019396	Bonobo	19	symbol	gene, protein-coding, MODEL [RefSeq]
12209354	CLEC4G	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate binding (inferred); carbohydrate derivative binding (inferred); D-mannose binding (inferred); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH hepatocellular ca ... (more) rcinoma (ortholog); FOUND IN plasma membrane (inferred)	20	52476162	52480341	Dog	23	symbol	gene, protein-coding, MODEL [RefSeq]
12532069	Clec4g	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate binding (inferred); carbohydrate derivative binding (inferred); D-mannose binding (inferred); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH hepatocellular ca ... (more) rcinoma (ortholog); FOUND IN plasma membrane (inferred)	NW_004936588	4737278	4740750	Squirrel	19	symbol	gene, protein-coding, MODEL [RefSeq]
14015124	CLEC4G	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate binding (inferred); carbohydrate derivative binding (inferred); D-mannose binding (inferred); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH hepatocellular ca ... (more) rcinoma (ortholog); FOUND IN plasma membrane (inferred); INTERACTS WITH deoxynivalenol; zearalenone				Pig	25	symbol	gene, protein-coding, VALIDATED [RefSeq]
18918612	Clec4g	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate binding (inferred); carbohydrate derivative binding (inferred); D-mannose binding (inferred); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH hepatocellular ca ... (more) rcinoma (ortholog); FOUND IN plasma membrane (inferred)				Naked Mole-Rat	19	symbol	gene, protein-coding, MODEL [RefSeq]
626024548	Clec4g	C-type lectin domain family 4 member G	ENCODES a protein that exhibits carbohydrate derivative binding (ortholog); D-mannose binding (ortholog); fructose binding (ortholog); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); positive regulation of viral life cyc ... (more) le (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN plasma membrane (ortholog)				Black Rat	19	symbol	gene, protein-coding, MODEL [RefSeq]
18778950	LOC103233812	C-type lectin domain family 4 member G	ENCODES a protein that exhibits polysaccharide binding (ortholog); INVOLVED IN negative regulation of T cell mediated immunity (ortholog); negative regulation of T cell proliferation (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN membrane (inferred); plasma membrane (infer ... (more) red)				Green Monkey	21	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
40841307	AC008763.4	novel protein, readthrough CD209 - CLEC4G					Human		name	gene, protein-coding
1625847	CLEC4GP1	C-type lectin domain family 4 member G pseudogene 1	INTERACTS WITH benzo[a]pyrene; cisplatin	19	7787484	7791012	Human	2	symbol , COSMIC , Human Proteome Map	gene, pseudo, VALIDATED [RefSeq]