Clec4g (C-type lectin domain family 4, member g) - Rat Genome Database

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Gene: Clec4g (C-type lectin domain family 4, member g) Mus musculus
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Symbol: Clec4g
Name: C-type lectin domain family 4, member g
RGD ID: 1557774
MGI Page MGI
Description: Exhibits polysaccharide binding activity. Involved in negative regulation of T cell mediated immunity and negative regulation of T cell proliferation. Localizes to plasma membrane. Orthologous to human CLEC4G (C-type lectin domain family 4 member G); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; benzo[b]fluoranthene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930572L20Rik; C-type lectin domain family 4 member G
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,757,066 - 3,770,695 (-)NCBIGRCm39mm39
GRCm39 Ensembl83,757,064 - 3,770,651 (-)Ensembl
GRCm3883,707,066 - 3,720,695 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,707,064 - 3,720,651 (-)EnsemblGRCm38mm10GRCm38
MGSCv3783,716,071 - 3,720,651 (-)NCBIGRCm37mm9NCBIm37
MGSCv3683,716,077 - 3,720,651 (-)NCBImm8
Celera83,946,232 - 3,950,812 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821   PMID:19632227   PMID:20562862   PMID:21257728   PMID:21677750  
PMID:22884358   PMID:23118208   PMID:23487419   PMID:24769443   PMID:25957769   PMID:27184407   PMID:27480124   PMID:30301800  


Genomics

Comparative Map Data
Clec4g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,757,066 - 3,770,695 (-)NCBIGRCm39mm39
GRCm39 Ensembl83,757,064 - 3,770,651 (-)Ensembl
GRCm3883,707,066 - 3,720,695 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,707,064 - 3,720,651 (-)EnsemblGRCm38mm10GRCm38
MGSCv3783,716,071 - 3,720,651 (-)NCBIGRCm37mm9NCBIm37
MGSCv3683,716,077 - 3,720,651 (-)NCBImm8
Celera83,946,232 - 3,950,812 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
CLEC4G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl197,728,958 - 7,733,906 (-)EnsemblGRCh38hg38GRCh38
GRCh38197,728,957 - 7,732,110 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37197,793,843 - 7,797,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,699,850 - 7,703,005 (-)NCBINCBI36hg18NCBI36
Build 34197,699,851 - 7,703,006NCBI
Celera197,664,968 - 7,668,182 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef197,463,587 - 7,466,801 (-)NCBIHuRef
CHM1_1197,793,562 - 7,796,776 (-)NCBICHM1_1
Clec4g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2121,780,370 - 1,785,027 (-)NCBI
Rnor_6.0 Ensembl122,273,941 - 2,277,169 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0122,273,649 - 2,278,594 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0124,434,464 - 4,439,027 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,412,875 - 2,416,940 (+)NCBIRGSC3.4rn4RGSC3.4
Celera123,635,478 - 3,641,645 (-)NCBICelera
Cytogenetic Map12p12NCBI
Clec4g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,571,288 - 1,575,979 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555631,571,374 - 1,574,901 (+)NCBIChiLan1.0ChiLan1.0
CLEC4G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1197,870,550 - 7,873,699 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl197,870,730 - 7,873,631 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0197,015,848 - 7,019,396 (-)NCBIMhudiblu_PPA_v0panPan3
CLEC4G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,476,162 - 52,480,341 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2052,476,200 - 52,479,930 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,279,523 - 52,283,613 (-)NCBI
ROS_Cfam_1.02053,005,016 - 53,009,106 (-)NCBI
UMICH_Zoey_3.12052,208,486 - 52,218,901 (-)NCBI
UNSW_CanFamBas_1.02052,652,069 - 52,656,165 (-)NCBI
UU_Cfam_GSD_1.02052,883,279 - 52,887,375 (-)NCBI
Clec4g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118213,094,033 - 213,097,594 (+)NCBI
SpeTri2.0NW_0049365884,737,278 - 4,740,750 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLEC4G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1271,433,406 - 71,436,570 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,967,726 - 71,970,446 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233812
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,206,303 - 7,211,213 (-)NCBI
ChlSab1.1 Ensembl67,206,712 - 7,209,431 (-)Ensembl
Vero_WHO_p1.0NW_023666081636,814 - 640,084 (+)NCBI
Clec4g
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624828775,114 - 778,526 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131723288Mouse
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124701082Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130397432Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:915
Count of miRNA genes:489
Interacting mature miRNAs:570
Transcripts:ENSMUST00000058040, ENSMUST00000062037, ENSMUST00000159612, ENSMUST00000160527
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000058040   ⟹   ENSMUSP00000136805
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,707,064 - 3,717,553 (-)Ensembl
RefSeq Acc Id: ENSMUST00000062037   ⟹   ENSMUSP00000059574
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,716,064 - 3,720,651 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159612
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,717,214 - 3,718,653 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160527   ⟹   ENSMUSP00000124493
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,707,064 - 3,717,553 (-)Ensembl
RefSeq Acc Id: NM_029465   ⟹   NP_083741
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,766,071 - 3,770,651 (-)NCBI
GRCm3883,716,071 - 3,720,651 (-)NCBI
MGSCv3783,716,071 - 3,720,651 (-)RGD
Celera83,946,232 - 3,950,812 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_870085
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,757,066 - 3,770,695 (-)NCBI
GRCm3883,707,066 - 3,720,695 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083741   ⟸   NM_029465
- UniProtKB: Q8BNX1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000124493   ⟸   ENSMUST00000160527
RefSeq Acc Id: ENSMUSP00000059574   ⟸   ENSMUST00000062037
RefSeq Acc Id: ENSMUSP00000136805   ⟸   ENSMUST00000058040
Protein Domains
C-type lectin

Promoters
RGD ID:6842948
Promoter ID:MM_KWN:53507
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000053519
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3683,720,426 - 3,720,926 (-)MPROMDB
RGD ID:8666355
Promoter ID:EPDNEW_M11209
Type:multiple initiation site
Name:Clec4g_1
Description:Mus musculus C-type lectin domain family 4, member g , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3883,720,653 - 3,720,713EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923113 AgrOrtholog
Ensembl Genes ENSMUSG00000046787
  ENSMUSG00000074491 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000059574 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000124493 UniProtKB/TrEMBL
  ENSMUSP00000136805 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000058040 UniProtKB/TrEMBL
  ENSMUST00000062037 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000160527 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/Swiss-Prot
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75863 UniProtKB/Swiss-Prot
MGD MGI:1923113 ENTREZGENE
NCBI Gene 75863 ENTREZGENE
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Clec4g PhenoGen
PROSITE C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CLC4G_MOUSE UniProtKB/Swiss-Prot
  F6T066_MOUSE UniProtKB/TrEMBL
  Q8BNX1 ENTREZGENE
  Q9D4Q9_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q5I0T7 UniProtKB/Swiss-Prot
  Q8R188 UniProtKB/Swiss-Prot