| 1346600 | CD79A | CD79a molecule | The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Thi s gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] | 19 | 41877279 | 41881372 | Human | 161 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1617637 | Cd79a | CD79A antigen (immunoglobulin-associated alpha) | Enables transmembrane signaling receptor activity. Involved in B cell differentiation; B cell proliferation; and B cell receptor signaling pathway. Located in external side of plasma membrane; membrane raft; and multivesicular body. Part of B cell receptor complex. Is expressed in liver. Human ortho log(s) of this gene implicated in agammaglobulinemia 3. Orthologous to human CD79A (CD79a molecule). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 24596922 | 24601283 | Mouse | 460 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 6484896 | Cd79a | CD79a molecule | ENCODES a protein that exhibits identical protein binding (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN B cell activation (ortholog); B cell differentiation (ortholog); B cell proliferation (ortholog); PARTICIPATES IN B cell receptor signaling pathway; primary immunod eficiency pathway; ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (ortholog); external side of plasma membrane (ortholog); IgM B cell receptor complex (ortholog); INTERACTS WITH bisphenol A; copper atom; copper(0) | 1 | 89621460 | 89625813 | Rat | 109 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8799060 | Cd79a | CD79a molecule | ENCODES a protein that exhibits identical protein binding (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN B cell activation (ortholog); B cell differentiation (ortholog); B cell proliferation (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (ortholog); external side of plasma membrane (ortholog); IgM B cell receptor complex (ortholog) | NW_004955555 | 961522 | 965605 | Chinchilla | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11770363 | CD79A | CD79a molecule | ENCODES a protein that exhibits identical protein binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN B cell receptor signaling pathway (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (inferred); external side of plasma membrane (inferred); IgM B cell receptor complex (inferred) | 19 | 38765067 | 38769556 | Bonobo | 35 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12267628 | CD79A | CD79a molecule | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); identical protein binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN B cell receptor signaling pathway (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN IgM B cell receptor complex (ortholog) | 1 | 112411281 | 112414827 | Dog | 66 | symbol , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12683631 | Cd79a | CD79a molecule | ENCODES a protein that exhibits identical protein binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN B cell receptor signaling pathway (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (inferred); external side of plasma membrane (inferred); IgM B cell receptor complex (inferred) | NW_004936706 | 561195 | 564577 | Squirrel | 33 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14057517 | CD79A | CD79a molecule | ENCODES a protein that exhibits identical protein binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN B cell receptor signaling pathway (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (inferred); external side of plasma membrane (inferred); IgM B cell receptor complex (inferred) | | | | Pig | 36 | symbol , old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18640476 | CD79A | CD79a molecule | ENCODES a protein that exhibits identical protein binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN B cell receptor signaling pathway (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (inferred); external side of plasma membrane (inferred); IgM B cell receptor complex (inferred) | | | | Green Monkey | 32 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18921542 | Cd79a | CD79a molecule | ENCODES a protein that exhibits identical protein binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN B cell receptor signaling pathway (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (inferred); external side of plasma membrane (inferred); IgM B cell receptor complex (inferred) | | | | Naked Mole-Rat | 33 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 20865946 | CD79A | CD79a molecule | | | | | Green Monkey | | symbol , name | gene, protein-coding |
| 329329938 | cd79a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626088146 | Cd79a | CD79a molecule | ENCODES a protein that exhibits identical protein binding (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN B cell activation (ortholog); B cell differentiation (ortholog); B cell proliferation (ortholog); ASSOCIATED WITH agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); agammaglobulinemia 3 (ortholog); FOUND IN B cell receptor complex (ortholog); external side of plasma membrane (ortholog); IgM B cell receptor complex (ortholog) | | | | Black Rat | 27 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 284402353 | cd79a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288057344 | cd79a.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 62303 | Igbp1 | immunoglobulin (CD79A) binding protein 1 | Enables mitogen-activated protein kinase kinase binding activity and protein domain specific binding activity. Involved in positive regulation of dephosphorylation and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of apoptotic signaling pat hway. Located in cytoplasm and microtubule. Is expressed in central nervous system and genitourinary system. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to several human genes including IGBP1 (immunoglobulin binding protein 1). [provided by Alliance of Genome Resources, Jul 2025] | X | 99537897 | 99559731 | Mouse | 114 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1558010 | Igbp1b | immunoglobulin (CD79A) binding protein 1b | Predicted to enable protein phosphatase 2A binding activity. Predicted to be involved in regulation of dephosphorylation. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in bladder; central nervous syst em; testis; ureter; and urethra of male. Orthologous to human IGBP1C (IGBP1 family member C). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 138634087 | 138635452 | Mouse | 16 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1560971 | Igbp1b | immunoglobulin (CD79A) binding protein 1b | INVOLVED IN regulation of signal transduction (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A | 4 | 173260206 | 173261556 | Rat | 3 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 16565937 | AC073387.2 | immunoglobulin (CD79A) binding protein 1, pseudogene | | 7 | 109763681 | 109764377 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 62011 | Igbp1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits protein phosphatase 2A binding; protein-containing complex binding; enzyme binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of apoptotic signaling pathway (ortholog); negative regulation of stress-activated MAPK cascade (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); microtubule (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide | X | 69622925 | 69645167 | Rat | 100 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 732872 | IGBP1 | immunoglobulin binding protein 1 | The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. [provided by RefSeq, Jul 2008] | X | 70133447 | 70166324 | Human | 143 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 9008032 | Igbp1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits enzyme binding (ortholog); mitogen-activated protein kinase kinase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of apoptotic signaling pathway (ortholog); negative regulat ion of stress-activated MAPK cascade (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); microtubule (ortholog) | NW_004955475 | 9671162 | 9694926 | Chinchilla | 39 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12041667 | IGBP1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits enzyme binding (ortholog); mitogen-activated protein kinase kinase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN negative regulation of apoptotic signaling pathway (ortholog); positive regulation of dephosphorylation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); microtubule (ortholog) | X | 59401426 | 59434363 | Bonobo | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12369548 | IGBP1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits protein phosphatase 2A binding (ortholog); protein phosphatase regulator activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of apoptotic signaling pathway (ortholog); negati ve regulation of stress-activated MAPK cascade (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); microtubule (inferred) | X | 54558515 | 54612029 | Dog | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12638132 | Igbp1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits protein phosphatase 2A binding (ortholog); protein phosphatase regulator activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of apoptotic signaling pathway (ortholog); negati ve regulation of stress-activated MAPK cascade (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); microtubule (inferred) | NW_004936762 | 1292572 | 1319145 | Squirrel | 44 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14177331 | IGBP1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits protein phosphatase 2A binding (ortholog); protein phosphatase regulator activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of apoptotic signaling pathway (ortholog); negati ve regulation of stress-activated MAPK cascade (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); microtubule (inferred) | | | | Pig | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18665954 | IGBP1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits protein phosphatase 2A binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN negative regulation of apoptotic signaling pathway (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma- micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); microtubule (inferred) | | | | Green Monkey | 43 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18900461 | Igbp1 | immunoglobulin binding protein 1 | ENCODES a protein that exhibits enzyme binding (ortholog); mitogen-activated protein kinase kinase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); negative regulation of apoptotic signaling pathway (ortholog); negative regulat ion of stress-activated MAPK cascade (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); microtubule (ortholog) | | | | Naked Mole-Rat | 39 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 5683681 | IGBP1C | IGBP1 family member C | Predicted to enable protein phosphatase 2A binding activity. Predicted to be involved in regulation of dephosphorylation. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Jul 2025] | 17 | 58660424 | 58692045 | Human | 4 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1353136 | IGBP1P1 | IGBP1 pseudogene 1 | INTERACTS WITH cadmium dichloride; sodium arsenite | 14 | 34939922 | 34940496 | Human | 2 | old_gene_name | gene, pseudo, VALIDATED [RefSeq] |
| 5683696 | IGBP1P3 | IGBP1 pseudogene 3 | | 3 | 32620700 | 32621914 | Human | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 5683694 | IGBP1P4 | IGBP1 pseudogene 4 | INTERACTS WITH aristolochic acid A | 4 | 82401419 | 82402607 | Human | 1 | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 5683695 | IGBP1P5 | IGBP1 pseudogene 5 | | 4 | 27585134 | 27586305 | Human | | old_gene_name | gene, pseudo, INFERRED [RefSeq] |
| 12150137 | RPS19 | ribosomal protein S19 | ENCODES a protein that exhibits fibroblast growth factor binding (inferred); identical protein binding (inferred); structural constituent of ribosome (inferred); INVOLVED IN erythrocyte differentiation (ortholog); Notch signaling pathway (ortholog); PARTICIPATES IN ribosome biogenesis pathway; trans lation pathway; ASSOCIATED WITH congenital hypoplastic anemia (ortholog); Diamond-Blackfan anemia (ortholog); Diamond-Blackfan anemia 1 (ortholog); FOUND IN synapse (ortholog) | 1 | 112418800 | 112427445 | Dog | 63 | ensembl_gene_symbol , ensembl_full_name | gene, protein-coding, MODEL [RefSeq] |