| 736436 | CD244 | CD244 molecule | This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Altern atively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] | 1 | 160830160 | 160862887 | Human | 111 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8949623 | Cd244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN myeloid dendritic cell activation (ortholog); natural killer cell activation (ortholog); natural killer cell activation involved in immune response (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); membrane raft (ortholog) | NW_004955468 | 12532937 | 12559859 | Chinchilla | 26 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 9330179 | Cd244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN myeloid dendritic cell activation (ortholog); natural killer cell activation (ortholog); natural killer cell activation involved in immune response (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); membrane raft (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride | 13 | 86583727 | 86606902 | Rat | 74 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 12040729 | CD244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (inferred); signaling receptor activity (inferred); INVOLVED IN myeloid dendritic cell activation (ortholog); positive regulation of CD8-positive, alpha-beta T cell proliferation (ortholog); positive regulation of natural killer cell prolif eration (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred); membrane raft (inferred) | 1 | 136186906 | 136219669 | Bonobo | 30 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12152539 | CD244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (inferred); signaling receptor activity (inferred); INVOLVED IN myeloid dendritic cell activation (ortholog); positive regulation of CD8-positive, alpha-beta T cell proliferation (ortholog); positive regulation of natural killer cell prolif eration (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred); membrane raft (inferred) | 38 | 21495649 | 21522656 | Dog | 31 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12602764 | Cd244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN myeloid dendritic cell activation (ortholog); natural killer cell activation (ortholog); natural killer cell activation involved in immune response (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); membrane raft (ortholog) | NW_004936903 | 146108 | 162410 | Squirrel | 26 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14088765 | CD244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (inferred); signaling receptor activity (inferred); INVOLVED IN myeloid dendritic cell activation (ortholog); positive regulation of CD8-positive, alpha-beta T cell proliferation (ortholog); positive regulation of natural killer cell prolif eration (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (inferred); membrane (inferred); membrane raft (inferred); INTERACTS WITH zearalenone | | | | Pig | 32 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18445170 | CD244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN myeloid dendritic cell activation (ortholog); natural killer cell activation (ortholog); natural killer cell activation involved in immune response (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); membrane raft (ortholog) | | | | Green Monkey | 26 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18922246 | Cd244 | CD244 molecule | ENCODES a protein that exhibits signaling receptor activity (ortholog); INVOLVED IN myeloid dendritic cell activation (ortholog); natural killer cell activation (ortholog); positive regulation of CD8-positive, alpha-beta T cell proliferation (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rh eumatoid arthritis (ortholog); FOUND IN membrane raft (ortholog) | | | | Naked Mole-Rat | 27 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 20865844 | CD244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (inferred); signaling receptor activity (inferred); INVOLVED IN natural killer cell activation (inferred); natural killer cell activation involved in immune response (inferred); positive regulation of granzyme B production (inferred); FOUND IN external side of plasma membrane (inferred); membrane (inferred); membrane raft (inferred) | | | | Green Monkey | 15 | symbol , name | gene, protein-coding |
| 625836872 | Cd244 | CD244 molecule | ENCODES a protein that exhibits MHC class I protein binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN myeloid dendritic cell activation (ortholog); natural killer cell activation (ortholog); natural killer cell activation involved in immune response (ortholog); ASSOCIATED WITH prostate cancer (ortholog); rheumatoid arthritis (ortholog); FOUND IN external side of plasma membrane (ortholog); membrane raft (ortholog) | | | | Black Rat | 25 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 733643 | Cd244a | CD244 molecule A | Predicted to enable MHC class I protein binding activity. Involved in myeloid dendritic cell activation; natural killer cell activation involved in immune response; and positive regulation of lymphocyte proliferation. Located in external side of plasma membrane. Is expressed in thymus primordium. Hu man ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human CD244 (CD244 molecule). [provided by Alliance of Genome Resources, Apr 2025] | 1 | 171386761 | 171412884 | Mouse | 92 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 68400 | Cd244l1 | CD244 molecule like 1 | FOUND IN membrane (inferred); membrane raft (inferred); plasma membrane (inferred) | 13 | 86547250 | 86569026 | Rat | 8 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1347470 | AKAP8L | A-kinase anchoring protein 8 like | Enables histone deacetylase binding activity and lamin binding activity. Involved in several processes, including cell cycle G2/M phase transition; mitotic chromosome condensation; and regulation of mRNA export from nucleus. Located in chromatin; cytoplasm; and nuclear lumen. Part of ribonucleoprote in complex. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 15380050 | 15418988 | Human | 153 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 734400 | ATP5F1A | ATP synthase F1 subunit alpha | This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalyti c core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012] | 18 | 46080248 | 46104227 | Human | 443 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1350585 | BNIP3L | BCL2 interacting protein 3 like | This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release o f cytochrome c. [provided by RefSeq, Feb 2015] | 8 | 26383054 | 26413127 | Human | 291 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1346675 | CBLN4 | cerebellin 4 precursor | This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorect al cancer receptor. [provided by RefSeq, Aug 2012] | 20 | 55997357 | 56005519 | Human | 59 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 733156 | GPD1 | glycerol-3-phosphate dehydrogenase 1 | This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to g lycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] | 12 | 50104008 | 50111313 | Human | 254 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1605626 | JHY | junctional cadherin complex regulator | Predicted to be involved in axoneme assembly and brain development. Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; motile cilium assembly; and regulation of establishment of planar polarity. Predicted to be located in extracellular region. [provi ded by Alliance of Genome Resources, Jul 2025] | 11 | 122882759 | 122963862 | Human | 37 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 5688622 | LINC00343 | long intergenic non-protein coding RNA 343 | | 13 | 105706830 | 105761796 | Human | | GenBank Nucleotide | gene, ncrna, VALIDATED [RefSeq] |
| 1605379 | NKAPD1 | NKAP domain containing 1 | Enables identical protein binding activity. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 112074299 | 112085150 | Human | 33 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1350390 | PKIG | cAMP-dependent protein kinase inhibitor gamma | This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in os teogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | 20 | 44531875 | 44619037 | Human | 87 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 7245141 | PRC1-AS1 | PRC1 antisense RNA 1 | INTERACTS WITH all-trans-retinoic acid; cadmium atom; cadmium dichloride | 15 | 90966369 | 90988624 | Human | 4 | GenBank Nucleotide | gene, ncrna, VALIDATED [RefSeq] |
| 1353124 | SNUPN | snurportin 1 | The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene inter acts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] | 15 | 75598086 | 75626461 | Human | 127 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1603015 | STAMBPL1 | STAM binding protein like 1 | Enables K63-linked deubiquitinase activity. Involved in cellular response to L-leucine and positive regulation of TORC1 signaling. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 10 | 88880245 | 88923487 | Human | 132 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1316350 | TMEM242 | transmembrane protein 242 | Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 157289025 | 157323519 | Human | 57 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1318550 | TTC3 | tetratricopeptide repeat domain 3 | Enables ubiquitin-protein transferase activity. Involved in protein K48-linked ubiquitination and ubiquitin-dependent protein catabolic process. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 21 | 37073254 | 37203118 | Human | 147 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 38646908 | ZC3H11C | zinc finger CCCH-type containing 11C | Predicted to enable zinc ion binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 65301476 | 65306574 | Human | 6 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1601812 | ZNG1E | Zn regulated GTPase metalloprotein activator 1E | Predicted to enable GTPase activity and zinc chaperone activity. Predicted to be involved in protein maturation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 9 | 65652979 | 65734041 | Human | 31 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |