| 2295 | Ccng1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling; negative regulation of apoptotic process; response to gravity; PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH breast cancer; hepatocellular carcinoma; muscular atrophy; FOUND IN dendrite; neuronal cell body; perinuclear region of cytopl asm; INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate | 10 | 25678503 | 25684876 | Rat | 356 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 735830 | CCNG1 | cyclin G1 | The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) seq uence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] | 5 | 163437571 | 163457640 | Human | 363 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 735831 | Ccng1 | cyclin G1 | Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; mitotic G2 DNA damage checkpoint signaling; and syncytium formation. Predicted to be located in dendrite; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); localized osteosarcoma; ovarian cancer (multiple); and sarcoma. Orthologous to human CCNG1 (cyclin G1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 40639379 | 40646044 | Mouse | 375 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8913203 | Ccng1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); nucleoplasm (ortholog) | NW_004955408 | 16846050 | 16850365 | Chinchilla | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12007788 | CCNG1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog) | 5 | 158814563 | 158822019 | Bonobo | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12092795 | CCNG1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog) | 4 | 47800697 | 47808259 | Dog | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12554045 | Ccng1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004936515 | 614287 | 621213 | Squirrel | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250785 | ccng1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626151688 | Ccng1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 40893885 | CCNG1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Green Monkey | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18905930 | Ccng1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13915225 | CCNG1 | cyclin G1 | INVOLVED IN mitotic G2 DNA damage checkpoint signaling (ortholog); negative regulation of apoptotic process (ortholog); response to gravity (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); breast adenocarcinoma (ortholog); breast cancer (ortholog); F OUND IN dendrite (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 58 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155250784 | ccng1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155253569 | ccng1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 4888880 | CCNG1P1 | cyclin G1 pseudogene 1 | | 6 | 132698595 | 132699673 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
