| 1309728 | Cbr3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity; carbonyl reductase (NADPH) activity; NADPH binding (ortholog); INVOLVED IN phylloquinone catabolic process; cognition (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; arachidonic acid metabolic p athway; ASSOCIATED WITH autism spectrum disorder (ortholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil | 11 | 46478295 | 46486555 | Rat | 211 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320224 | CBR3 | carbonyl reductase 3 | Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons sp anning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008] | 21 | 36135079 | 36146562 | Human | 216 | symbol , old_gene_name , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320225 | Cbr3 | carbonyl reductase 3 | Predicted to enable NADPH binding activity; NADPH dehydrogenase (quinone) activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in cognition and phylloquinone catabolic process. Predicted to be located in cytosol and nucleoplasm . Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Orthologous to human CBR3 (carbonyl reductase 3). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 93480107 | 93487879 | Mouse | 228 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8788361 | Cbr3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); NADPH binding (ortholog); INVOLVED IN cognition (ortholog); phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics path way; ASSOCIATED WITH autism spectrum disorder (ortholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytosol (ortholog) | NW_004955407 | 35419674 | 35428270 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11807857 | CBR3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); INVOLVED IN phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (o rtholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | 21 | 22505647 | 22516938 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12430191 | CBR3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); INVOLVED IN phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (o rtholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | 31 | 31416441 | 31423797 | Dog | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12619917 | Cbr3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); INVOLVED IN phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (o rtholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | NW_004936500 | 6461776 | 6469063 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907711 | Cbr3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); NADPH binding (ortholog); INVOLVED IN cognition (ortholog); phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics path way; ASSOCIATED WITH autism spectrum disorder (ortholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytosol (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13970939 | CBR3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); INVOLVED IN phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (o rtholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | | | | Pig | 28 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 625899349 | Cbr3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); NADPH binding (ortholog); INVOLVED IN cognition (ortholog); phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics path way; ASSOCIATED WITH autism spectrum disorder (ortholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytosol (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18523749 | CBR3 | carbonyl reductase 3 | ENCODES a protein that exhibits 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); INVOLVED IN phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (o rtholog); Familial Platelet Disorder with Associated Myeloid Malignancy (ortholog); Mouth Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred) | | | | Green Monkey | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 5687877 | CBR3-AS1 | CBR3 antisense RNA 1 | INTERACTS WITH beta-lapachone; cadmium dichloride; nickel atom | 21 | 36131767 | 36156308 | Human | 4 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 14037989 | LOC100622246 | carbonyl reductase [NADPH] 1 | ENCODES a protein that exhibits 15-hydroxyprostaglandin dehydrogenase (NADP+) activity (inferred); 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity (inferred); alcohol dehydrogenase [NAD(P)+] activity (inferred); INVOLVED IN lipid metabolic process (inferred); FOUND IN cytoplasm (inferred) | | | | Pig | 13 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 16561414 | AC009248.1 | carbonyl reductase 3 (CBR3) pseudogene | | 12 | 45200885 | 45201530 | Human | | name | gene, pseudo, INFERRED [RefSeq] |