Cbr3 (carbonyl reductase 3) - Rat Genome Database

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Gene: Cbr3 (carbonyl reductase 3) Chinchilla lanigera
Analyze
Symbol: Cbr3
Name: carbonyl reductase 3
RGD ID: 8788361
Description: ENCODES a protein that exhibits 3-keto sterol reductase activity (ortholog); carbonyl reductase (NADPH) activity (ortholog); NADPH binding (ortholog); INVOLVED IN cognition (ortholog); phylloquinone catabolic process (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 7 (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: carbonyl reductase [NADPH] 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540735,419,674 - 35,428,270 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540735,419,674 - 35,428,270 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Cbr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540735,419,674 - 35,428,270 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540735,419,674 - 35,428,270 (+)NCBIChiLan1.0ChiLan1.0
CBR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382136,135,079 - 36,146,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2136,135,079 - 36,146,562 (+)EnsemblGRCh38hg38GRCh38
GRCh372137,507,377 - 37,518,860 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,429,133 - 36,440,730 (+)NCBINCBI36Build 36hg18NCBI36
Build 342136,364,264 - 36,440,724NCBI
Celera2122,706,132 - 22,717,559 (+)NCBICelera
Cytogenetic Map21q22.12NCBI
HuRef2122,984,935 - 22,996,359 (+)NCBIHuRef
CHM1_12137,069,046 - 37,080,642 (+)NCBICHM1_1
T2T-CHM13v2.02134,518,104 - 34,529,412 (+)NCBIT2T-CHM13v2.0
Cbr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391693,480,107 - 93,487,879 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1693,480,103 - 93,487,878 (+)EnsemblGRCm39 Ensembl
GRCm381693,683,219 - 93,690,991 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1693,683,215 - 93,690,990 (+)EnsemblGRCm38mm10GRCm38
MGSCv371693,683,464 - 93,691,236 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361693,571,759 - 93,579,527 (+)NCBIMGSCv36mm8
Celera1694,777,963 - 94,785,655 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1654.58NCBI
Cbr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81146,478,295 - 46,486,555 (+)NCBIGRCr8
mRatBN7.21133,008,615 - 33,016,877 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,008,615 - 33,016,875 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,662,664 - 41,670,924 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01134,334,206 - 34,342,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01133,484,246 - 33,492,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01133,909,417 - 33,917,674 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1133,909,439 - 33,917,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01137,500,661 - 37,508,918 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41133,913,961 - 33,922,221 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11133,961,819 - 33,978,463 (+)NCBI
Celera1135,427,193 - 35,435,432 (-)NCBICelera
Cytogenetic Map11q11NCBI
CBR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22232,256,031 - 32,267,414 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12127,115,995 - 27,128,098 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02122,505,647 - 22,516,938 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12135,865,374 - 35,876,717 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2135,865,374 - 35,876,717 (+)Ensemblpanpan1.1panPan2
CBR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13131,416,441 - 31,423,797 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3131,416,333 - 31,423,739 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3130,472,787 - 30,480,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03130,713,351 - 30,720,605 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3130,713,139 - 30,720,547 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13130,585,631 - 30,592,893 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03130,599,689 - 30,606,933 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03131,090,527 - 31,097,817 (+)NCBIUU_Cfam_GSD_1.0
Cbr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497130,998,820 - 31,006,047 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365006,458,721 - 6,591,928 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365006,461,776 - 6,469,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13199,830,668 - 199,840,442 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113199,830,690 - 199,840,444 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213209,842,863 - 209,852,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CBR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1280,158,842 - 80,164,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl280,158,806 - 80,164,248 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660547,988,123 - 7,999,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474527,294,222 - 27,305,109 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474527,298,714 - 27,305,606 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000011858   ⟹   ENSCLAP00000011720
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540735,419,674 - 35,428,270 (+)Ensembl
RefSeq Acc Id: XM_005375724   ⟹   XP_005375781
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540735,419,674 - 35,428,270 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504553   ⟹   XP_013360007
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540735,419,674 - 35,428,270 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005375781 (Get FASTA)   NCBI Sequence Viewer  
  XP_013360007 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000011720
  ENSCLAP00000011720.1
RefSeq Acc Id: XP_005375781   ⟸   XM_005375724
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VDB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360007   ⟸   XM_013504553
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCLAP00000011720   ⟸   ENSCLAT00000011858


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008082 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000011858 ENTREZGENE
  ENSCLAT00000011858.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro CBR1-like UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene Cbr3 ENTREZGENE
PANTHER CARBONYL REDUCTASE 1-RELATED UniProtKB/TrEMBL
  CARBONYL REDUCTASE [NADPH] 3 UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A8C2VDB8 ENTREZGENE, UniProtKB/TrEMBL