| 1311551 | Amfr | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (ortholog); identical protein binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN learning or memory; endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); PARTICIPATES IN Endoplasmic Reticu lum-associated degradation pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite; growth cone; neuronal cell body; INTERACTS WITH bisphenol A; gentamycin; indole-3-methanol | 19 | 11002451 | 11038182 | Rat | 141 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323068 | AMFR | autocrine motility factor receptor | This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum -associated degradation of specific proteins. [provided by RefSeq, Feb 2012] | 16 | 56361452 | 56425545 | Human | 169 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1323069 | Amfr | autocrine motility factor receptor | Predicted to enable several functions, including BAT3 complex binding activity; ubiquitin-specific protease binding activity; and ubiquitin-ubiquitin ligase activity. Involved in negative regulation of canonical Wnt signaling pathway and regulation of SREBP signaling pathway. Predicted to be located in several cellular components, including growth cone; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of Derlin-1 retrotranslocation complex and ubiquitin ligase complex. Predicted to be active in cytosol and endoplasmic reticulum. Is expressed in several structures, including central nervous system; genitourinary system; integumental system; liver; and retina nuclear layer. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 89. Orthologous to human AMFR (autocrine motility factor receptor). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 94698216 | 94739301 | Mouse | 178 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8930557 | Amfr | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (ortholog); identical protein binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); learning or memory (ortholog); ASSOCIATED WITH Alzheim er's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); Derlin-1 retrotranslocation complex (ortholog); endoplasmic reticulum (ortholog) | NW_004955433 | 14172871 | 14205484 | Chinchilla | 61 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12027702 | AMFR | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN learning or memory (ortholog); regulation of SREBP signaling pathway (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); bre ast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); growth cone (ortholog); neuronal cell body (ortholog) | 16 | 36647792 | 36711782 | Bonobo | 68 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12118088 | AMFR | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN learning or memory (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); growth cone (ortholog); neuronal cell body (ortholog) | 2 | 59766910 | 59803292 | Dog | 67 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12693852 | Amfr | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN learning or memory (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); growth cone (ortholog); neuronal cell body (ortholog) | NW_004936475 | 8692969 | 8727252 | Squirrel | 68 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18935013 | Amfr | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN learning or memory (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); growth cone (ortholog); neuronal cell body (ortholog) | | | | Naked Mole-Rat | 68 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155233247 | amfr | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18603859 | AMFR | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN learning or memory (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); growth cone (ortholog); neuronal cell body (ortholog) | | | | Green Monkey | 68 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626084717 | Amfr | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (ortholog); identical protein binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); learning or memory (ortholog); ASSOCIATED WITH Alzheim er's disease (ortholog); amenorrhea (ortholog); breast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); Derlin-1 retrotranslocation complex (ortholog); endoplasmic reticulum (ortholog) | | | | Black Rat | 61 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14285695 | AMFR | autocrine motility factor receptor | ENCODES a protein that exhibits BAT3 complex binding (inferred); identical protein binding (inferred); metal ion binding (inferred); INVOLVED IN learning or memory (ortholog); regulation of SREBP signaling pathway (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amenorrhea (ortholog); bre ast ductal carcinoma (ortholog); FOUND IN dendrite (ortholog); growth cone (ortholog); neuronal cell body (ortholog) | | | | Pig | 67 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155233248 | amfr.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258513 | amfr.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16562846 | AC092140.1 | novel transcript, antisense to AMFR | | | | | Human | | name | gene, lncrna |