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45 records found for search term Afap1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
619959Afap1actin filament associated protein 1ENCODES a protein that exhibits SH2 domain binding; SH3 domain binding; molecular adaptor activity (ortholog); INVOLVED IN cellular response to mechanical stimulus; regulation of signal transduction; lactation (ortholog); ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN actin filament; actin147896796179081032Rat115symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1605642AFAP1actin filament associated protein 1The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript 477587137939861Human113symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1623955Afap1actin filament associated protein 1Predicted to enable SH2 domain binding activity and SH3 domain binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in actin cytoskeleton and focal adhesion. Predicted to be active in actin filament and cytosol. Is expressed in cerebral cortex subv53605071336161267Mouse128symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9010466Afap1actin filament associated protein 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (orthNW_00495551429341153050347Chinchilla13symbolgene, protein-coding, MODEL [RefSeq]
12021040AFAP1actin filament associated protein 1ENCODES a protein that exhibits SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN actin filament (ortholoBonobo18symbolgene, protein-coding, MODEL [RefSeq]
12336801AFAP1actin filament associated protein 1ENCODES a protein that exhibits SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN actin filament (ortholo35968688759828924Dog18symbolgene, protein-coding, MODEL [RefSeq]
12709284Afap1actin filament associated protein 1ENCODES a protein that exhibits SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN actin filament (ortholoNW_0049364771928807519418543Squirrel19symbolgene, protein-coding, MODEL [RefSeq]
14230972AFAP1actin filament associated protein 1ENCODES a protein that exhibits SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN actin filament (ortholoPig18symbolgene, protein-coding, PROVISIONAL [RefSeq]
18618078AFAP1actin filament associated protein 1ENCODES a protein that exhibits SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN actin filament (ortholoGreen Monkey18symbolgene, protein-coding, MODEL [RefSeq]
18922279Afap1actin filament associated protein 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (orthNaked Mole-Rat19symbolgene, protein-coding, MODEL [RefSeq]
155243580afap1Tropical Clawed Frogsymbolgene, null
626108352Afap1actin filament associated protein 1ENCODES a protein that exhibits molecular adaptor activity (ortholog); SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); lactation (ortholog); lipid biosynthetic process (ortholog); ASSOCIATED WITH open-angle glaucoma (orthBlack Rat13symbolgene, protein-coding, MODEL [RefSeq]
155243581afap1.LAfrican Clawed Frogsymbolgene, null
155232336afap1.SAfrican Clawed Frogsymbolgene, null
4107292AFAP1-AS1AFAP1 antisense RNA 1This gene produces a long non-coding RNA that is overexpressed in tumor cells and may promote cancer cell metastasis. [provided by RefSeq, Dec 2017]477540907778928Human10symbol , COSMIC , name , Human Proteome Map , old_gene_symbolgene, ncrna, REVIEWED [RefSeq]
16572256AFAP1-AS2AFAP1 antisense RNA 2477985277808053Humansymbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, ncrna, MODEL [RefSeq]
1311580Afap1l1actin filament associated protein 1-like 1ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); podosome (inferred); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil185745412057514584Rat84symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1323113Afap1l1actin filament associated protein 1-like 1Predicted to be located in several cellular components, including actin cytoskeleton; anchoring junction; and cell projection. Predicted to be active in cytosol. Is expressed in diaphragm; heart; lung; and vertebral axis musculature. Orthologous to human AFAP1L1186186333361919733Mouse85symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1606158AFAP1L1actin filament associated protein 1 like 1Predicted to be located in several cellular components, including actin cytoskeleton; anchoring junction; and cell projection. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Jul 2025]5149271859149343637Human84symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1321706AFAP1L2actin filament associated protein 1 like 2Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. L10114280725114405175Human108symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1321707Afap1l2actin filament associated protein 1-like 2Predicted to enable SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Predicted to be involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulat195690078657017021Mouse136symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1585231Grpel2GrpE-like 2, mitochondrialENCODES a protein that exhibits unfolded protein binding (ortholog); INVOLVED IN protein folding (inferred); PARTICIPATES IN presequence pathway of mitochondrial protein import; FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide185743816857450408Rat98old_gene_name , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
8770015Afap1l1actin filament associated protein 1 like 1ASSOCIATED WITH neuromuscular disease (ortholog)NW_00495541550798765140905Chinchilla3symbolgene, protein-coding, MODEL [RefSeq]
11940596AFAP1L1actin filament associated protein 1 like 1ENCODES a protein that exhibits SH3 domain binding (inferred); ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); cytosol (inferred)5144698397144767606Bonobo8symbolgene, protein-coding, MODEL [RefSeq]
12358912AFAP1L1actin filament associated protein 1 like 1ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); podosome (inferred)45961775959650194Dog7symbolgene, protein-coding, MODEL [RefSeq]
12575779Afap1l1actin filament associated protein 1 like 1ENCODES a protein that exhibits SH3 domain binding (inferred); ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); cytosol (inferred)NW_00493650455252765587348Squirrel8symbolgene, protein-coding, MODEL [RefSeq]
14169928AFAP1L1actin filament associated protein 1 like 1ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); podosome (inferred)Pig7symbolgene, protein-coding, VALIDATED [RefSeq]
18371302AFAP1L1actin filament associated protein 1 like 1ENCODES a protein that exhibits SH3 domain binding (inferred); ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); cytosol (inferred)Green Monkey8symbolgene, protein-coding, MODEL [RefSeq]
18904708Afap1l1actin filament associated protein 1 like 1ENCODES a protein that exhibits SH3 domain binding (inferred); ASSOCIATED WITH neuromuscular disease (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); cytosol (inferred)Naked Mole-Rat8symbolgene, protein-coding, MODEL [RefSeq]
285893930afap1l1Tropical Clawed Frogsymbolgene, null
625838711Afap1l1actin filament associated protein 1 like 1ASSOCIATED WITH neuromuscular disease (ortholog)Black Rat3symbolgene, protein-coding, MODEL [RefSeq]
1310668Afap1l2actin filament associated protein 1-like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (ortholog); SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN inflammatory response (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of epidermal growth fa1265969368266065951Rat119symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
9000249Afap1l2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (ortholog); SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN inflammatory response (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of epidermal growth faNW_0049554311927525719378507Chinchilla13symbolgene, protein-coding, MODEL [RefSeq]
11746925AFAP1L2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (inferred); SH2 domain binding (inferred); SH3 domain binding (inferred); INVOLVED IN inflammatory response (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of epidermal growth fa10110894774111004373Bonobo23symbolgene, protein-coding, MODEL [RefSeq]
12319458AFAP1L2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (inferred); SH2 domain binding (inferred); SH3 domain binding (inferred); INVOLVED IN inflammatory response (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of epidermal growth fa282513723525228454Dog20symbolgene, protein-coding, MODEL [RefSeq]
12451788Afap1l2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (inferred); SH2 domain binding (inferred); SH3 domain binding (inferred); INVOLVED IN inflammatory response (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of epidermal growth faNW_00493648646065294697481Squirrel23symbolgene, protein-coding, MODEL [RefSeq]
14064541AFAP1L2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (inferred); SH2 domain binding (inferred); SH3 domain binding (inferred); INVOLVED IN inflammatory response (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of epidermal growth faPig20symbolgene, protein-coding, MODEL [RefSeq]
18450902AFAP1L2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (inferred); SH2 domain binding (inferred); SH3 domain binding (inferred); INVOLVED IN inflammatory response (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of epidermal growth faGreen Monkey23symbolgene, protein-coding, MODEL [RefSeq]
18924869Afap1l2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (ortholog); INVOLVED IN inflammatory response (inferred); positive regulation of DNA-templated transcription (inferred); positive regulation of epidermal growth factor receptor signaling pathway (inferred); ASSOCIATED WITH sqNaked Mole-Rat13symbolgene, protein-coding, MODEL [RefSeq]
284682497afap1l2Tropical Clawed Frogsymbolgene, null
626079920Afap1l2actin filament associated protein 1 like 2ENCODES a protein that exhibits protein tyrosine kinase activator activity (ortholog); SH2 domain binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN inflammatory response (ortholog); positive regulation of DNA-templated transcription (ortholog); positive regulation of epidermal growth faBlack Rat13symbolgene, protein-coding, MODEL [RefSeq]
285779425afap1l1.LAfrican Clawed Frogsymbolgene, null
284979701afap1l1.SAfrican Clawed Frogsymbolgene, null
286172067afap1l2.LAfrican Clawed Frogsymbolgene, null
286814644afap1l2.SAfrican Clawed Frogsymbolgene, null