| 621792 | Actn3 | actinin alpha 3 | ENCODES a protein that exhibits actin filament binding (ortholog); identical protein binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); focal adhesion assembly (ortholog); negative regulation of calcineurin-NFAT signaling cascade (ortholog); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; Entamoebiasis pathway; systemic lupus erythematosus pathway; FOUND IN brush border (ortholog); focal adhesion (ortholog); sarcomere (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene | 1 | 211588473 | 211604401 | Rat | 154 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 734136 | ACTN3 | actinin alpha 3 | This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Apr 2024] | 11 | 66546395 | 66563334 | Human | 155 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 734137 | Actn3 | actinin alpha 3 | This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. [provided by RefSeq, Sep 20 15] | 19 | 4911244 | 4927937 | Mouse | 137 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8890366 | Actn3 | actinin alpha 3 | ENCODES a protein that exhibits actin filament binding (ortholog); identical protein binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); focal adhesion assembly (ortholog); negative regulation of calcineurin-NFAT signaling cascade (ortholog); FOUND IN brush border (ortholog); focal adhesion (ortholog); sarcomere (ortholog) | NW_004955422 | 18799372 | 18812458 | Chinchilla | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11819253 | ACTN3 | actinin alpha 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calcium ion binding (inferred); INVOLVED IN osteoblast differentiation (ortholog); FOUND IN actin cytoskeleton (inferred); brush border (inferred); cell junction (inferred) | 11 | 61905722 | 61922227 | Bonobo | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12316701 | ACTN3 | actinin alpha 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calcium ion binding (inferred); INVOLVED IN osteoblast differentiation (ortholog); FOUND IN actin cytoskeleton (inferred); brush border (inferred); focal adhesion (inferred); INTERACTS WITH bisphenol A | 18 | 50787353 | 50801036 | Dog | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12473994 | Actn3 | actinin alpha 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calcium ion binding (inferred); INVOLVED IN osteoblast differentiation (ortholog); FOUND IN actin cytoskeleton (inferred); brush border (inferred); cytoplasm (inferred) | NW_004936599 | 3033854 | 3046364 | Squirrel | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14371976 | Actn3 | | | | | | Fly | | symbol | gene, null |
| 13849689 | ACTN3 | actinin alpha 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calcium ion binding (inferred); INVOLVED IN osteoblast differentiation (ortholog); FOUND IN actin cytoskeleton (inferred); brush border (inferred); focal adhesion (inferred) | | | | Pig | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18478748 | ACTN3 | actinin alpha 3 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); calcium ion binding (inferred); INVOLVED IN osteoblast differentiation (ortholog); FOUND IN actin cytoskeleton (inferred); brush border (inferred); cell junction (inferred) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626011302 | Actn3 | actinin alpha 3 | ENCODES a protein that exhibits actin filament binding (ortholog); identical protein binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); focal adhesion assembly (ortholog); negative regulation of calcineurin-NFAT signaling cascade (ortholog); FOUND IN brush border (ortholog); focal adhesion (ortholog); sarcomere (ortholog) | | | | Black Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238087 | actn3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18916271 | Actn3 | actinin alpha 3 | ENCODES a protein that exhibits actin filament binding (ortholog); identical protein binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN bone morphogenesis (ortholog); focal adhesion assembly (ortholog); negative regulation of calcineurin-NFAT signaling cascade (ortholog); FOUND IN brush border (ortholog); focal adhesion (ortholog); sarcomere (ortholog) | | | | Naked Mole-Rat | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238086 | actn3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862208 | actn3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858710 | actn3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469010 | actn3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856112 | actn3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857895 | actn3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 597621595 | ACTN3-AS1 | ACTN3 antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |
