| 628661 | Abca5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN late endosome (ortholog); lysosome (ortholog); INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 1,3-dinitrobenzene; 17alpha-ethynylestradiol | 10 | 95739610 | 95808633 | Rat | 158 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1300038 | ABCA5 | ATP binding cassette subfamily A member 5 | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GC N20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] | 17 | 69244311 | 69327133 | Human | 178 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551371 | Abca5 | ATP-binding cassette, sub-family A member 5 | Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Involved in several processes, including cholesterol efflux; negative regulation of macrophage derived foam cell differentiation; and regulation of cholesterol transport. Located in late endosome an d lysosome. Is expressed in cortical hem. Orthologous to human ABCA5 (ATP binding cassette subfamily A member 5). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 110160195 | 110228542 | Mouse | 171 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8981152 | Abca5 | ATP binding cassette subfamily A member 5 | INVOLVED IN cholesterol efflux (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN late endosome (ortholog); lysosome (ortholog) | NW_004955478 | 3526376 | 3586811 | Chinchilla | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11827961 | ABCA5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (inferred); cholesterol homeostasis (inferred); cholesterol metabolic process (inferred); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); late endosome (inferred); late endosome membrane (inferred) | 17 | 63172670 | 63255587 | Bonobo | 33 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12089460 | ABCA5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (inferred); cholesterol homeostasis (inferred); cholesterol metabolic process (inferred); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); late endosome (inferred); late endosome membrane (inferred); INTERACTS WITH masitinib | 9 | 15708070 | 15781100 | Dog | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12462250 | Abca5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (inferred); cholesterol homeostasis (inferred); cholesterol metabolic process (inferred); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); late endosome (inferred); late endosome membrane (inferred) | NW_004936541 | 8467035 | 8549893 | Squirrel | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18540737 | ABCA5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (inferred); cholesterol homeostasis (inferred); cholesterol metabolic process (inferred); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); late endosome (inferred); late endosome membrane (inferred) | | | | Green Monkey | 33 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155235303 | abca5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14281604 | ABCA5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (inferred); cholesterol homeostasis (inferred); cholesterol metabolic process (inferred); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); late endosome (inferred); late endosome membrane (inferred) | | | | Pig | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907386 | Abca5 | ATP binding cassette subfamily A member 5 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN cholesterol efflux (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN Golgi membrane (inferred); late endosome (inferred); late endosome membrane (inferred) | | | | Naked Mole-Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626156902 | Abca5 | ATP binding cassette subfamily A member 5 | INVOLVED IN cholesterol efflux (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN transport pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Generalized Hypertrichosis Terminalis, with or without Gingival Hyperplasia (ortholog); genetic disease (ortholog); FOUND IN late endosome (ortholog); lysosome (ortholog) | | | | Black Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155254397 | abca5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241395 | abca5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 12133534 | ABCA6 | ATP binding cassette subfamily A member 6 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN transmembrane transport (inferred); ASSOCIATED WITH allergic contact dermatitis (ortholog); Colorectal Neoplasms (ortholog); FOUND IN Golgi membrane (infe rred); membrane (inferred); nucleoplasm (inferred) | 9 | 15587837 | 15648639 | Dog | 17 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12269572 | ABCA9 | ATP binding cassette subfamily A member 9 | ENCODES a protein that exhibits ABC-type transporter activity (inferred); ATP binding (inferred); ATP hydrolysis activity (inferred); INVOLVED IN transmembrane transport (inferred); ASSOCIATED WITH Colorectal Neoplasms (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS W ITH bisphenol A | 9 | 15515462 | 15574890 | Dog | 14 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |