Strain Report - Rat Genome Database
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Strain: NP

Symbol: NP
Strain: NP
Full Name: alcohol-nonpreferring
RGD ID: 634381
RRID: RGD_634381
Ontology ID: RS:0000610
Alleles: Npy
Type: inbred
Source: Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
Origin: These were developed at Indiana University for low-alcohol-preferring behavior through bidirectional selective breeding of Wistar rats.
Last Known Status: Unknown

Mutant Strains



Strain QTL Data
Symbol Name Trait
Alc18 Alcohol consumption QTL 18 drinking behavior trait   (VT:0001422)    
Alc19 Alcohol consumption QTL 19 drinking behavior trait   (VT:0001422)    
Alc20 Alcohol consumption QTL 20 drinking behavior trait   (VT:0001422)    
Alc21 Alcohol consumption QTL 21 drinking behavior trait   (VT:0001422)    
Alc8 Alcohol consumption QTL 8 consumption behavior trait   (VT:0002069)    
Sach1 Saccharin preference QTL 1 consumption behavior trait   (VT:0002069)    
Sach2 Saccharin preference QTL 2 consumption behavior trait   (VT:0002069)    
Sach3 Saccharin preference QTL 3 consumption behavior trait   (VT:0002069)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics These have low voluntary oral consumption of alcohol which results in low blood alcohol. 69704
strain_other strain contains polymorphism at position +4666 in the second intron with sequence GAGAGAG; associated with differential expression level of Npy gene 1357412
strain_phys_biochem Vamp2 mRNA is downregulated in frontal cortex compared with P strain 1358772