GWAS1662804_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1662804_H (HbA1c measurement QTL GWAS1662804 (human)) Homo sapiens

Symbol: GWAS1662804_H
Name: HbA1c measurement QTL GWAS1662804 (human)
RGD ID: 597605944
Trait: HbA1c measurement
Measurement Type: blood hemoglobin A1c level   (CMO:0002786)    
LOD Score: Not Available
P Value: 6.0E-28
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3816,591,668 - 6,591,669RGD_MAPPER_PIPELINEGRCh38
GRCh3716,651,728 - 6,651,729RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1662804_HHumanblood hemoglobin A1c level  IAGPrs1556036405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1662804_HHumanHbA1c measurement  IAGPrs1556036405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1351698KLHL21kelch like family member 21165907246602869Human


Peak: (rs1556036)
Human AssemblyChrPosition (strand)Source
GRCh3816,591,668 - 6,591,669RGD_MAPPER_PIPELINE


1 to 10 of 10 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597579614GWAS1636474_Hdiabetes mellitus QTL GWAS1636474 (human)3e-25pancreas integrity trait (VT:0010560)165916686591669Human
597594684GWAS1651544_Hglucose measurement QTL GWAS1651544 (human)2e-18glucose measurementblood glucose level (CMO:0000046)165916686591669Human
597578346GWAS1635206_Hobesity QTL GWAS1635206 (human)3e-15glucose measurementblood glucose level (CMO:0000046)165916686591669Human
597606427GWAS1663287_HHbA1c measurement QTL GWAS1663287 (human)1e-27HbA1c measurementblood hemoglobin A1c level (CMO:0002786)165916686591669Human
597579640GWAS1636500_Htype 2 diabetes mellitus QTL GWAS1636500 (human)2e-26type 2 diabetes mellitus165916686591669Human
597605944GWAS1662804_HHbA1c measurement QTL GWAS1662804 (human)6e-28HbA1c measurementblood hemoglobin A1c level (CMO:0002786)165916686591669Human
597598679GWAS1655539_HHbA1c measurement QTL GWAS1655539 (human)5e-12HbA1c measurementblood hemoglobin A1c level (CMO:0002786)165916686591669Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597579089GWAS1635949_Hovernutrition, obesity QTL GWAS1635949 (human)8e-14overnutrition, obesity165916686591669Human

1 to 10 of 10 rows


1 to 9 of 9 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1662804_H GCST90475094 Hemoglobin A1c (HbA1c, mean, inv-norm transformed) 338,848 European ancestry individuals C 0.679 6E-28 27.222 rs1556036 0.03555 HbA1c measurement (EFO:0004541)
 PMID:39024449
GWAS1635206_H GCST90475762 Obesity (PheCode 278.1) 169,600 European ancestry cases, 244,254 European ancestry controls C 0.6797 3E-15 14.523 rs1556036 0.03461 obesity (EFO:0001073)
 PMID:39024449
GWAS1635949_H GCST90475759 Overweight, obesity and other hyperalimentation (PheCode 278) 187,880 European ancestry cases, 218,356 European ancestry controls C 0.6796 8E-14 13.097 rs1556036 0.0334 obesity (EFO:0001073)
 PMID:39024449
GWAS1636474_H GCST90475658 Diabetes mellitus (PheCode 250) 154,958 European ancestry cases, 276,347 European ancestry controls C 0.6796 3E-25 24.523 rs1556036 0.04523 diabetes mellitus (EFO:0000400)
 PMID:39024449
GWAS1636500_H GCST90475667 Type 2 diabetes (PheCode 250.2) 154,194 European ancestry cases, 278,454 European ancestry controls C 0.6796 2E-26 25.699 rs1556036 0.04589 PMID:39024449
None Available GCST90475329 Glucose (fasting status unknown, maximum, inv-norm transformed) 419,671 European ancestry individuals C 0.6796 3E-15 14.523 rs1556036 0.02253 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1651544_H GCST90475332 Glucose (fasting status unknown, mean, inv-norm transformed) 419,946 European ancestry individuals C 0.6796 2E-18 17.699 rs1556036 0.02555 glucose measurement (EFO:0004468)
 PMID:39024449
GWAS1655539_H GCST90479502 Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) 98,578 African American or Afro-Caribbean individuals, 49,152 Hispanic or Latin American individuals, 5,466 East Asian ancestry individuals, 338,640 European ancestry individuals C 0.7094 5E-12 11.302 rs1556036 0.0242 HbA1c measurement (EFO:0004541)
 PMID:39024449
GWAS1663287_H GCST90475097 Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) 338,640 European ancestry individuals C 0.679 1E-27 27 rs1556036 0.03504 HbA1c measurement (EFO:0004541)
 PMID:39024449
1 to 9 of 9 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90475094 GWAS Catalog

Note Type Note Reference