GWAS1645094_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS1645094_H (diabetic neuropathy QTL GWAS1645094 (human)) Homo sapiens

Symbol: GWAS1645094_H
Name: diabetic neuropathy QTL GWAS1645094 (human)
RGD ID: 597588234
Trait: gestational diabetes
Measurement Type: body mass index (BMI)   (CMO:0000105)    
LOD Score: Not Available
P Value: 4.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3810112,998,590 - 112,998,591RGD_MAPPER_PIPELINEGRCh38
GRCh3710114,758,349 - 114,758,350RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645094_HHumanMaternal diabetes  IAGPrs7903146405850206 GWAS_CATALOGPMID:35220425

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645094_HHumanbody mass index (BMI)  IAGPrs7903146405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1645094_HHumanbody mass index  IAGPrs7903146405850206 GWAS_CATALOGPMID:39024449
GWAS1645094_HHumandiabetic neuropathy  IAGPrs7903146405850206 GWAS_CATALOGPMID:39024449
GWAS1645094_HHumangestational diabetes  IAGPrs7903146405850206 GWAS_CATALOGPMID:35220425

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1317786TCF7L2transcription factor 7 like 210112950247113167678Human
38650396LOC110121472VISTA enhancer hs198010112997945112998897Human


Peak: (rs7903146)
Human AssemblyChrPosition (strand)Source
GRCh3810112,998,590 - 112,998,591RGD_MAPPER_PIPELINE


1 to 10 of 236 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597587870GWAS1644730_Hdiabetic neuropathy QTL GWAS1644730 (human)8e-236diabetic neuropathy10112998590112998591Human
597587871GWAS1644731_Htype 2 diabetes nephropathy QTL GWAS1644731 (human)2e-17body mass (VT:0001259)body weight (CMO:0000012)10112998590112998591Human
407128647GWAS777623_Htype 2 diabetes mellitus, metabolic syndrome QTL GWAS777623 (human)0.0000007glucose tolerance test10112998590112998591Human
597588890GWAS1645750_Hglucose measurement QTL GWAS1645750 (human)9e-101glucose measurementblood glucose level (CMO:0000046)10112998590112998591Human
597257621GWAS1353695_HBMI-adjusted waist-hip ratio QTL GWAS1353695 (human)1e-13BMI-adjusted waist-hip ratio10112998590112998591Human
597616019GWAS1672879_Hnephritis QTL GWAS1672879 (human)4e-17nephritisblood total cholesterol level (CMO:0000051)10112998590112998591Human
597256586GWAS1352660_Htype 2 diabetes mellitus QTL GWAS1352660 (human)6e-18type 2 diabetes mellitus10112998590112998591Human
407125584GWAS774560_Htype 2 diabetes mellitus QTL GWAS774560 (human)3e-19type 2 diabetes mellitus10112998590112998591Human
597589382GWAS1646242_Htype 1 diabetes mellitus QTL GWAS1646242 (human)4e-98type 1 diabetes mellitus10112998590112998591Human
597135758GWAS1231832_Hgestational diabetes QTL GWAS1231832 (human)4e-16gestational diabetes10112998590112998591Human

1 to 10 of 236 rows


1 to 20 of 323 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1645094_H GCST90475674 Type 2 diabetes with neurological manifestations (PheCode 250.24) 7,320 Hispanic or Latin American cases, 50,236 Hispanic or Latin American controls C 0.7391 4E-16 15.398 rs7903146 0.1711 diabetic neuropathy (EFO:1000783)
PMID:39024449
GWAS1699246_H GCST004066 Hip circumference up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.2858 7E-8 7.155 rs7903146 0.0298 hip circumference (OBA:1000032)
PMID:25673412
GWAS1699365_H GCST001526 Fasting blood insulin (BMI interaction) Up to 51,750 European ancestry individuals T 0.2871 0.000003 5.523 rs7903146 7.362E-4 body mass index (EFO:0004340)
blood insulin amount (OBA:VT0001560)
PMID:22581228
GWAS1699378_H GCST001527 Fasting blood glucose (BMI interaction) Up to 58,074 European ancestry individuals T 0.2886 2E-14 13.699 rs7903146 0.0024 obsolete_fasting blood glucose measurement (EFO:0004465)
body mass index (EFO:0004340)
PMID:22581228
GWAS1699445_H GCST005186 Fasting blood glucose Up to 58,074 European ancestry individuals T 0.2876 1E-9 9 rs7903146 0.0212 obsolete_fasting blood glucose measurement (EFO:0004465)
PMID:22581228
GWAS1699452_H GCST005185 Fasting blood insulin Up to 51,750 European ancestry individuals T 0.2724 3E-7 6.523 rs7903146 0.0185 blood insulin amount (OBA:VT0001560)
PMID:22581228
None Available GCST004066 Hip circumference up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.2858 0.000003 5.523 rs7903146 0.0239 hip circumference (OBA:1000032)
PMID:25673412
GWAS1699596_H GCST004066 Hip circumference up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.2858 2E-11 10.699 rs7903146 0.0264 hip circumference (OBA:1000032)
PMID:25673412
GWAS539606_H GCST000712 Type 2 diabetes 8,130 European ancestry cases, 38,987 European ancestry controls T NR 2E-51 50.699 rs7903146 1.4 PMID:20581827
GWAS1115971_H GCST005951 Body mass index up to 309,889 European ancestry individuals T 0.28797015591893 3E-13 12.523 rs7903146 0.021989034 body mass index (EFO:0004340)
PMID:26426971
GWAS1117618_H GCST004758 Type 2 diabetes 2,499 Hispanic/Latino ancestry cases, 5,247 Hispanic/Latino ancestry controls T 0.25 1E-11 11 rs7903146 1.36 PMID:28254843
GWAS1635325_H GCST90475685 Polyneuropathy in diabetes (PheCode 250.6) 4,528 African American or Afro-Caribbean cases, 114,074 African American or Afro-Caribbean controls C 0.7058 2E-22 21.699 rs7903146 0.226 PMID:39024449
GWAS1635335_H GCST90475686 Polyneuropathy in diabetes (PheCode 250.6) 18,533 European ancestry cases, 421,371 European ancestry controls C 0.7051 1E-76 76 rs7903146 0.2019 PMID:39024449
GWAS1635337_H GCST90479652 PT international normalized ratio (INR, minimum, inv-norm transformed) 49,241 African American or Afro-Caribbean individuals, 23,426 Hispanic or Latin American individuals, 1,793 East Asian ancestry individuals, 165,202 European ancestry individuals C 0.7101 9E-13 12.046 rs7903146 0.02501 prothrombin time measurement (EFO:0008390)
PMID:39024449
GWAS1635531_H GCST90479639 hemoglobin (mean, inv-norm transformed) 114,985 African American or Afro-Caribbean individuals, 55,838 Hispanic or Latin American individuals, 5,963 East Asian ancestry individuals, 407,894 European ancestry individuals C 0.7102 1E-33 33 rs7903146 0.03128 hemoglobin measurement (EFO:0004509)
PMID:39024449
GWAS1635615_H GCST90479630 hematocrit (minimum, inv-norm transformed) 114,988 African American or Afro-Caribbean individuals, 55,841 Hispanic or Latin American individuals, 5,964 East Asian ancestry individuals, 407,854 European ancestry individuals C 0.7102 1E-31 31 rs7903146 0.02994 hematocrit (EFO:0004348)
PMID:39024449
GWAS1635751_H GCST90479629 hematocrit (mean, inv-norm transformed) 114,988 African American or Afro-Caribbean individuals, 55,841 Hispanic or Latin American individuals, 5,964 East Asian ancestry individuals, 407,852 European ancestry individuals C 0.7102 2E-43 42.699 rs7903146 0.03734 hematocrit (EFO:0004348)
PMID:39024449
GWAS1635803_H GCST90475753 Hyperpotassemia (PheCode 276.13) 17,226 European ancestry cases, 415,141 European ancestry controls C 0.7047 2E-21 20.699 rs7903146 0.1095 Abnormality of metabolism/homeostasis (HP:0001939)
PMID:39024449
GWAS1635859_H GCST90475735 Gout (PheCode 274.1) 42,034 European ancestry cases, 397,989 European ancestry controls C 0.7041 2E-12 11.699 rs7903146 0.05243 gout (EFO:0004274)
PMID:39024449
None Available GCST90479638 hemoglobin (maximum, inv-norm transformed) 114,984 African American or Afro-Caribbean individuals, 55,834 Hispanic or Latin American individuals, 5,963 East Asian ancestry individuals, 407,887 European ancestry individuals C 0.7102 1E-33 33 rs7903146 0.03264 hemoglobin measurement (EFO:0004509)
PMID:39024449
1 to 20 of 323 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90239750 GWAS Catalog
  GCST90475158 GWAS Catalog
  GCST90475674 GWAS Catalog

Note Type Note Reference