GWAS1485738_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1485738_H (low density lipoprotein cholesterol measurement QTL GWAS1485738 (human)) Homo sapiens

Symbol: GWAS1485738_H
Name: low density lipoprotein cholesterol measurement QTL GWAS1485738 (human)
RGD ID: 597389664
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 9.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38116,186,091 - 16,186,092RGD_MAPPER_PIPELINEGRCh38
GRCh37116,512,586 - 16,512,587RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1485738_HHumanblood low density lipoprotein cholesterol level  IAGPrs12078100405850206 GWAS_CATALOGPMID:32203549

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1485738_HHumanlow density lipoprotein cholesterol measurement  IAGPrs12078100405850206 GWAS_CATALOGPMID:32203549

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs12078100)
Human AssemblyChrPosition (strand)Source
GRCh38116,186,091 - 16,186,092RGD_MAPPER_PIPELINE


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597412317GWAS1508391_Hlow density lipoprotein cholesterol measurement QTL GWAS1508391 (human)7e-13low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)11618609116186092Human
597367613GWAS1463687_Hapolipoprotein B measurement QTL GWAS1463687 (human)1e-12apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)11618609116186092Human
597389664GWAS1485738_Hlow density lipoprotein cholesterol measurement QTL GWAS1485738 (human)9e-10low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)11618609116186092Human
597404352GWAS1500426_Hlow density lipoprotein cholesterol measurement QTL GWAS1500426 (human)2e-24low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)11618609116186092Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human

1 to 9 of 9 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1485738_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals C 0.376912 9E-10 9.046 rs12078100 0.0131578 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS1463687_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals C 0.376908 1E-12 12 rs12078100 0.0152704 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
GWAS1500426_H GCST90002412 Low density lipoprotein cholesterol levels 431,167 European ancestry individuals C 0.376535 2E-24 23.699 rs12078100 0.0199294 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32493714
GWAS1508391_H GCST010204 Low density lipoprotein cholesterol levels 324,708 British ancestry individuals ? NR 7E-13 12.155 rs12078100 0.0187 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32154731
Database
Acc Id
Source(s)
GWAS Catalog GCST010245 GWAS Catalog

Note Type Note Reference