GWAS1432591_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1432591_H (C-reactive protein measurement QTL GWAS1432591 (human)) Homo sapiens

Symbol: GWAS1432591_H
Name: C-reactive protein measurement QTL GWAS1432591 (human)
RGD ID: 597336517
Trait: C-reactive protein measurement
Measurement Type: blood C-reactive protein level   (CMO:0003160)    
LOD Score: Not Available
P Value: 3.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38121,563,893 - 21,563,894RGD_MAPPER_PIPELINEGRCh38
GRCh37121,890,386 - 21,890,387RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1432591_HHumanblood C-reactive protein level  IAGPrs1256335405850206 GWAS_CATALOGPMID:36376304

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1432591_HHumanC-reactive protein measurement  IAGPrs1256335405850206 GWAS_CATALOGPMID:36376304

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1346147ALPLalkaline phosphatase, biomineralization associated12150898421578410Human


Peak: (rs1256335)
Human AssemblyChrPosition (strand)Source
GRCh38121,563,893 - 21,563,894RGD_MAPPER_PIPELINE


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597139223GWAS1235297_Hcholine phosphate measurement QTL GWAS1235297 (human)3e-43phosphocholine amount (VT:0011003)12156389321563894Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407024851GWAS673827_Hvitamin B6 measurement QTL GWAS673827 (human)1e-15vitamin B6 measurement12156389321563894Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597175588GWAS1271662_Hkynureninase measurement QTL GWAS1271662 (human)7e-12kynureninase measurement12156389321563894Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
597316855GWAS1412929_Hphosphoethanolamine measurement QTL GWAS1412929 (human)2e-31phosphoethanolamine measurement12156389321563894Human
407051804GWAS700780_Hphosphoenolpyruvic acid measurement QTL GWAS700780 (human)0.000001phosphoenolpyruvic acid measurement12156389321563894Human

1 to 10 of 11 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1432591_H GCST90179146 C-reactive protein levels (MTAG) 575,531 European ancestry individuals A NR 3E-10 9.523 rs1256335 0.015243 C-reactive protein measurement (EFO:0004458)
 PMID:36376304
GWAS673827_H GCST000483 Folate pathway vitamin levels 3,305 European ancestry females, 1,458 European ancestry males ? 0.21 1E-15 15 rs1256335 0.14 vitamin B6 measurement (EFO:0004621)
 PMID:19744961
GWAS700780_H GCST009391 Metabolite levels 2,076 European ancestry individuals ? NR 0.000001 6 rs1256335 0.24061082 phosphoenolpyruvic acid measurement (EFO:0010522)
 PMID:23823483
GWAS1235297_H GCST90245143 Choline phosphate levels 14,296 European ancestry individuals A 0.7696 3E-43 42.523 rs1256335 0.16522907 choline phosphate measurement (EFO:0800617)
 PMID:36357675
GWAS1271662_H GCST90248219 Kynureninase levels 10,708 European ancestry individuals A 0.78 7E-12 11.155 rs1256335 0.111 kynureninase measurement (EFO:0008201)
 PMID:34648354
GWAS1412929_H GCST90245377 Phosphoethanolamine levels 14,296 European ancestry individuals A 0.7708 2E-31 30.699 rs1256335 0.14521438 phosphoethanolamine measurement (EFO:0800600)
 PMID:36357675
Database
Acc Id
Source(s)
GWAS Catalog GCST90179146 GWAS Catalog

Note Type Note Reference