GWAS673827_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS673827_H (vitamin B6 measurement QTL GWAS673827 (human)) Homo sapiens

Symbol: GWAS673827_H
Name: vitamin B6 measurement QTL GWAS673827 (human)
RGD ID: 407024851
Trait: vitamin B6 measurement
LOD Score: Not Available
P Value: 1.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38121,563,893 - 21,563,894RGD_MAPPER_PIPELINEGRCh38
GRCh37121,890,386 - 21,890,387RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS673827_HHumanvitamin B6 measurement  IAGPrs1256335405850206 GWAS_CATALOGPMID:19744961
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1346147ALPLalkaline phosphatase, biomineralization associated12150898421578410Human

Position Markers

Peak: (rs1256335)
Human AssemblyChrPosition (strand)Source
GRCh38121,563,893 - 21,563,894RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407024851GWAS673827_Hvitamin B6 measurement QTL GWAS673827 (human)1e-15vitamin B6 measurement12156389321563894Human
406968707GWAS617683_Hkynureninase measurement QTL GWAS617683 (human)7e-12kynureninase measurement12156389321563894Human
406905241GWAS554217_Hcholine phosphate measurement QTL GWAS554217 (human)3e-43choline phosphate measurement12156389321563894Human
407310732GWAS959708_HC-reactive protein measurement QTL GWAS959708 (human)3e-10C-reactive protein measurementblood C-reactive protein level (CMO:0003160)12156389321563894Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407086463GWAS735439_Hphosphoethanolamine measurement QTL GWAS735439 (human)2e-31phosphoethanolamine measurement12156389321563894Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
407051804GWAS700780_Hphosphoenolpyruvic acid measurement QTL GWAS700780 (human)0.000001phosphoenolpyruvic acid measurement12156389321563894Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS554217_H GCST90245143 Choline phosphate levels 14,296 European ancestry individuals A 0.7696 3E-43 42.523 rs1256335 0.16522907 choline phosphate measurement (EFO:0800617)
 PMID:36357675
GWAS617683_H GCST90248219 Kynureninase levels 10,708 European ancestry individuals A 0.78 7E-12 11.155 rs1256335 0.111 kynureninase measurement (EFO:0008201)
 PMID:34648354
GWAS673827_H GCST000483 Folate pathway vitamin levels 3,305 European ancestry females, 1,458 European ancestry males ? 0.21 1E-15 15 rs1256335 0.14 vitamin B6 measurement (EFO:0004621)
 PMID:19744961
GWAS700780_H GCST009391 Metabolite levels 2,076 European ancestry individuals ? NR 0.000001 6 rs1256335 0.24061082 phosphoenolpyruvic acid measurement (EFO:0010522)
 PMID:23823483
GWAS735439_H GCST90245377 Phosphoethanolamine levels 14,296 European ancestry individuals A 0.7708 2E-31 30.699 rs1256335 0.14521438 phosphoethanolamine measurement (EFO:0800600)
 PMID:36357675
GWAS959708_H GCST90179146 C-reactive protein levels (MTAG) 575,531 European ancestry individuals A NR 3E-10 9.523 rs1256335 0.015243 C-reactive protein measurement (EFO:0004458)
 PMID:36376304
Database Acc Id Source(s)
GWAS Catalog GCST000483 GWAS Catalog

RGD Curation Notes
Note Type Note Reference