GWAS1312692_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1312692_H (response to beta blocker, mortality QTL GWAS1312692 (human)) Homo sapiens

Symbol: GWAS1312692_H
Name: response to beta blocker, mortality QTL GWAS1312692 (human)
RGD ID: 597216618
Trait: response to beta blocker, mortality
Measurement Type: ratio of deaths to total study population during a period of time   (CMO:0001023)    
LOD Score: Not Available
P Value: 8.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812104,806,310 - 104,806,311RGD_MAPPER_PIPELINEGRCh38
GRCh3712105,200,088 - 105,200,089RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1312692_HHumanratio of deaths to total study population during a period of time  IAGPrs9737956405850206 GWAS_CATALOGPMID:33012170

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1312692_HHumanmortality  IAGPrs9737956405850206 GWAS_CATALOGPMID:33012170
GWAS1312692_HHumanresponse to beta blocker  IAGPrs9737956405850206 GWAS_CATALOGPMID:33012170

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1316398SLC41A2solute carrier family 41 member 212104801801104958746Human


Peak: (rs9737956)
Human AssemblyChrPosition (strand)Source
GRCh3812104,806,310 - 104,806,311RGD_MAPPER_PIPELINE


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1559125SPSL2_HSerum P-selectin level QTL 2 (human)2.59Serum P-selectin level1289897665115897665Human
1298449UAE2_HUrinary albumin excretion QTL 2 (human)20.005Urinary albumin excretionurine albumin:creatinine ratio (ACR)12102836889128836889Human
597216618GWAS1312692_Hresponse to beta blocker, mortality QTL GWAS1312692 (human)0.000008response to beta blocker, mortalityratio of deaths to total study population during a period of time (CMO:0001023)12104806310104806311Human
1643258BW205_HBody weight QTL 205 (human)4.080.00001Body fat amountpercent body fat1296630114122630114Human
1643452BW104_HBody weight QTL 104 (human)1.890.005Body fat amountabdominal visceral12102395874128395874Human
1357361BW37_HBody weight QTL 37 (human)4.080.00001Body fat amount12102836889116423339Human
1643264BW195_HBody weight QTL 195 (human)0.0151Body weightBMI1289897665115897665Human
1357387BW58_HBody weight QTL 58 (human)2.30.0001Body weightfat free mass after exercise training1289438856115438856Human
1358827MULTSCL22_HMultiple sclerosis susceptibility QTL 22 (human)Multiple sclerosis susceptibility1289897665115897665Human

1 to 9 of 9 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1312692_H GCST010923 Beta blocker survival benefit in heart failure with reduced ejection fraction (time to all cause mortality x beta blocker interaction) 248 European ancestry individuals ? NR 0.000008 5.097 rs9737956 N/A response to beta blocker (EFO:0007766)
mortality (EFO:0004352)
 PMID:33012170
Database
Acc Id
Source(s)
GWAS Catalog GCST010923 GWAS Catalog

Note Type Note Reference