GWAS1310028_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1310028_H (blood protein measurement QTL GWAS1310028 (human)) Homo sapiens

Symbol: GWAS1310028_H
Name: blood protein measurement QTL GWAS1310028 (human)
RGD ID: 597213954
Trait: blood protein amount   (VT:0005416)    
Measurement Type: blood protein measurement   (CMO:0000028)    
LOD Score: Not Available
P Value: 2.0E-26
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38690,267,049 - 90,267,050RGD_MAPPER_PIPELINEGRCh38
GRCh37690,976,768 - 90,976,769RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1310028_HHumanblood protein measurement  IAGPrs72928038405850206 GWAS_CATALOGPMID:32929287

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1310028_HHumanblood protein amount  IAGPrs72928038405850206 GWAS_CATALOGPMID:32929287

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1310028_HHumanblood protein measurement  IAGPrs72928038405850206 GWAS_CATALOGPMID:32929287

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1319503BACH2BTB domain and CNC homolog 268992652890296843Human


Peak: (rs72928038)
Human AssemblyChrPosition (strand)Source
GRCh38690,267,049 - 90,267,050RGD_MAPPER_PIPELINE


1 to 10 of 52 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597281051GWAS1377125_Hrheumatoid arthritis QTL GWAS1377125 (human)6e-09rheumatoid arthritis69026704990267050Human
597212827GWAS1308901_Htype 2 diabetes mellitus QTL GWAS1308901 (human)1e-11type 2 diabetes mellitus69026704990267050Human
597208987GWAS1305061_Hblood protein measurement QTL GWAS1305061 (human)2e-13blood protein amount (VT:0005416)blood protein measurement (CMO:0000028)69026704990267050Human
597587480GWAS1644340_Hskin cancer QTL GWAS1644340 (human)7e-55skin cancer69026704990267050Human
597212816GWAS1308890_Hceliac disease QTL GWAS1308890 (human)0.0000004celiac disease69026704990267050Human
407006280GWAS655256_Hlymphocyte count QTL GWAS655256 (human)4e-41lymphocyte countblood lymphocyte count (CMO:0000031)69026704990267050Human
597075970GWAS1172044_HVitiligo QTL GWAS1172044 (human)1e-14Vitiligo69026704990267050Human
597253645GWAS1349719_Hnon-melanoma skin carcinoma QTL GWAS1349719 (human)3e-13non-melanoma skin carcinoma69026704990267050Human
597054595GWAS1150669_Hmultiple sclerosis QTL GWAS1150669 (human)8e-29multiple sclerosis69026704990267050Human
597604875GWAS1661735_Hskin neoplasm QTL GWAS1661735 (human)2e-16skin neoplasm69026704990267050Human

1 to 10 of 52 rows


1 to 20 of 56 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1310028_H GCST90001890 CD28 on CD45RA+ CD4+ T cell 2,920 Sardinian (founder/genetic isolate) ancestry individuals A 0.19897 2E-26 25.699 rs72928038 0.3653 blood protein measurement (EFO:0007937)
 PMID:32929287
GWAS549429_H GCST005537 Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) 8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls ? NR 2E-10 9.699 rs72928038 N/A ankylosing spondylitis (EFO:0003898)
psoriasis (EFO:0000676)
ulcerative colitis (EFO:0000729)
Crohn's disease (EFO:0000384)
More... 		PMID:26974007
GWAS1637594_H GCST90479663 lymphocyte (absolute count, maximum, inv-norm transformed) 70,548 African American or Afro-Caribbean individuals, 36,516 Hispanic or Latin American individuals, 3,839 East Asian ancestry individuals, 253,142 European ancestry individuals G 0.8623 3E-15 14.523 rs72928038 0.03721 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1637845_H GCST90479664 lymphocyte (absolute count, mean, inv-norm transformed) 70,580 African American or Afro-Caribbean individuals, 36,536 Hispanic or Latin American individuals, 3,839 East Asian ancestry individuals, 253,317 European ancestry individuals G 0.8623 8E-16 15.097 rs72928038 0.03783 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1638380_H GCST90479538 Skin cancer 431 African American or Afro-Caribbean cases, 55,074 African American or Afro-Caribbean controls, 55,282 European ancestry cases, 260,386 European ancestry controls, 979 Hispanic or Latin American cases, 28,335 Hispanic or Latin American controls G 0.8516 5E-25 24.302 rs72928038 0.1044 PMID:39024449
GWAS1639451_H GCST90475580 Other non-epithelial cancer of skin (PheCode 172.2) 68,143 European ancestry cases, 360,898 European ancestry controls G 0.8316 5E-47 46.302 rs72928038 0.1088 skin neoplasm (EFO:0004198)
 PMID:39024449
GWAS1642364_H GCST90475583 Squamous cell carcinoma (PheCode 172.22) 19,217 European ancestry cases, 419,674 European ancestry controls G 0.8316 4E-20 19.398 rs72928038 0.1313 squamous cell carcinoma (EFO:0000707)
 PMID:39024449
GWAS1642871_H GCST90475585 Neoplasm of uncertain behavior of skin (PheCode 173) 59,327 European ancestry cases, 338,779 European ancestry controls G 0.8319 7E-25 24.155 rs72928038 0.08497 skin neoplasm (EFO:0004198)
 PMID:39024449
GWAS568754_H GCST004627 Lymphocyte count 171,643 European ancestry individuals A 0.1783 4E-13 12.398 rs72928038 0.03408429 lymphocyte count (EFO:0004587)
 PMID:27863252
GWAS1126053_H GCST008870 Keratinocyte cancer (MTAG) at least 18,538 European ancestry cases, at least 340,302 European ancestry controls G 0.819182 1E-20 20 rs72928038 1.11 keratinocyte carcinoma (EFO:0010176)
 PMID:31174203
GWAS1644340_H GCST90475575 Skin cancer 83,801 European ancestry cases, 347,397 European ancestry controls G 0.8317 7E-55 54.155 rs72928038 0.1078 PMID:39024449
GWAS1644420_H GCST90475577 Melanomas of skin, dx or hx (PheCode 172.1) 45,274 European ancestry cases, 389,597 European ancestry controls G 0.8315 5E-27 26.302 rs72928038 0.09852 cutaneous melanoma (EFO:0000389)
 PMID:39024449
GWAS1127225_H GCST008872 Squamous cell carcinoma 9,674 European ancestry cases, 625,657 European ancestry controls G NR 5E-7 6.302 rs72928038 1.11 squamous cell carcinoma (EFO:0000707)
 PMID:31174203
GWAS1144365_H GCST007071 Autoimmune traits approximately 459,000 European ancestry individuals ? NR 5E-23 22.302 rs72928038 N/A autoimmune disease (EFO:0005140)
 PMID:30595370
GWAS1149053_H GCST005896 Non-melanoma skin cancer 5,912 European ancestry cases, 181,740 European ancestry controls A NR 0.000001 6 rs72928038 1.13286 non-melanoma skin carcinoma (EFO:0009260)
 PMID:29739929
GWAS1150669_H GCST009597 Multiple sclerosis 14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls A NR 8E-29 28.097 rs72928038 1.1543345 PMID:31604244
GWAS1652304_H GCST90475189 Skin cancer 55,282 European ancestry cases, 260,386 European ancestry controls G 0.8318 1E-33 33 rs72928038 0.1059 PMID:39024449
GWAS1160060_H GCST004863 Mosquito bite size 84,724 European ancestry individuals G NR 0.000008 5.097 rs72928038 0.0345724 mosquito bite reaction size measurement (EFO:0008378)
 PMID:28199695
GWAS1161344_H GCST005536 Type 1 diabetes 6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios A 0.17 6E-14 13.222 rs72928038 1.2 PMID:25751624
GWAS1654033_H GCST90475426 lymphocyte (absolute count, mean, inv-norm transformed) 253,317 European ancestry individuals G 0.8324 2E-27 26.699 rs72928038 0.04613 lymphocyte count (EFO:0004587)
 PMID:39024449
1 to 20 of 56 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90001890 GWAS Catalog

Note Type Note Reference