GWAS1236819_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1236819_H (low density lipoprotein cholesterol measurement QTL GWAS1236819 (human)) Homo sapiens

Symbol: GWAS1236819_H
Name: low density lipoprotein cholesterol measurement QTL GWAS1236819 (human)
RGD ID: 597140745
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 4.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38616,126,703 - 16,126,704RGD_MAPPER_PIPELINEGRCh38
GRCh37616,126,934 - 16,126,935RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1236819_HHumanblood low density lipoprotein cholesterol level  IAGPrs7746081405850206 GWAS_CATALOGPMID:36220816

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1236819_HHumanlow density lipoprotein cholesterol measurement  IAGPrs7746081405850206 GWAS_CATALOGPMID:36220816

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs7746081)
Human AssemblyChrPosition (strand)Source
GRCh38616,126,703 - 16,126,704RGD_MAPPER_PIPELINE


1 to 10 of 20 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
407061699GWAS710675_Hapolipoprotein B measurement QTL GWAS710675 (human)8e-24apolipoprotein B measurementblood apoliprotein B level (CMO:0000522)61612670316126704Human
597264857GWAS1360931_Hlow density lipoprotein cholesterol measurement QTL GWAS1360931 (human)4e-99low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)61612670316126704Human
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597051573GWAS1147647_Hlow density lipoprotein cholesterol measurement, physical activity QTL GWAS1147647 (human)2e-27low density lipoprotein cholesterol measurement, physical activityblood low density lipoprotein cholesterol level (CMO:0000053)61612670316126704Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597139865GWAS1235939_Htotal cholesterol measurement QTL GWAS1235939 (human)4e-10total cholesterol measurementblood total cholesterol level (CMO:0000051)61612670316126704Human

1 to 10 of 20 rows


1 to 9 of 9 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1236819_H GCST90244653 Low density lipoprotein cholesterol levels 29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals ? NR 4E-11 10.398 rs7746081 1.6627829 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:36220816
GWAS1131922_H GCST010245 LDL cholesterol levels 440,546 European ancestry individuals G 0.69589 5E-25 24.302 rs7746081 0.0234538 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32203549
GWAS1136852_H GCST010204 Low density lipoprotein cholesterol levels 324,708 British ancestry individuals ? NR 1E-39 39 rs7746081 0.0367 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32154731
GWAS1147647_H GCST007284 LDL cholesterol x physical activity interaction (2df test) 7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals A 0.3263 2E-27 26.699 rs7746081 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
physical activity (EFO:0003940)
 PMID:30670697
GWAS710675_H GCST010243 Apolipoprotein B levels 439,214 European ancestry individuals G 0.695862 8E-24 23.097 rs7746081 0.0227371 apolipoprotein B measurement (EFO:0004615)
 PMID:32203549
GWAS1235939_H GCST90244655 Total cholesterol levels 29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals ? NR 4E-10 9.398 rs7746081 1.6978357 total cholesterol measurement (EFO:0004574)
 PMID:36220816
GWAS1308427_H GCST006612 LDL cholesterol 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals A 0.4056 3E-12 11.523 rs7746081 0.0195 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30275531
GWAS1311178_H GCST006614 Total cholesterol levels 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals A 0.4055 6E-9 8.222 rs7746081 0.0163 total cholesterol measurement (EFO:0004574)
 PMID:30275531
GWAS1360931_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 4E-99 98.398 rs7746081 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
1 to 9 of 9 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90244653 GWAS Catalog

Note Type Note Reference