GWAS1226068_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1226068_H (diastolic blood pressure QTL GWAS1226068 (human)) Homo sapiens

Symbol: GWAS1226068_H
Name: diastolic blood pressure QTL GWAS1226068 (human)
RGD ID: 597129994
Trait: diastolic blood pressure
Measurement Type: diastolic blood pressure   (CMO:0000005)    
LOD Score: Not Available
P Value: 8E-120
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38111,835,738 - 11,835,739RGD_MAPPER_PIPELINEGRCh38
GRCh37111,895,795 - 11,895,796RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1226068_HHumandiastolic blood pressure  IAGPrs55857306405850206 GWAS_CATALOGPMID:38689001

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1226068_HHumandiastolic blood pressure  IAGPrs55857306405850206 GWAS_CATALOGPMID:38689001

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1313372CLCN6chloride voltage-gated channel 611180619111843130Human


Peak: (rs55857306)
Human AssemblyChrPosition (strand)Source
GRCh38111,835,738 - 11,835,739RGD_MAPPER_PIPELINE


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597052020GWAS1148094_Hsystolic blood pressure QTL GWAS1148094 (human)8e-89systolic blood pressuresystolic blood pressure (CMO:0000004)11183573811835739Human
597195516GWAS1291590_Hsystolic blood pressure QTL GWAS1291590 (human)5e-130systolic blood pressuresystolic blood pressure (CMO:0000004)11183573811835739Human
597461978GWAS1558052_Hdiastolic blood pressure QTL GWAS1558052 (human)5e-103diastolic blood pressurediastolic blood pressure (CMO:0000005)11183573811835739Human
596966707GWAS1086226_Hsystolic blood pressure QTL GWAS1086226 (human)3e-73systolic blood pressure11183573811835739Human
596977170GWAS1096689_Hhypertension QTL GWAS1096689 (human)4e-35hypertension11183573811835739Human
597324339GWAS1420413_Hsystolic blood pressure QTL GWAS1420413 (human)3e-73systolic blood pressuresystolic blood pressure (CMO:0000004)11183573811835739Human
597133725GWAS1229799_Hpulse pressure measurement QTL GWAS1229799 (human)3e-49pulse pressure measurementpulse pressure (CMO:0000292)11183573811835739Human
597166674GWAS1262748_Hserum alanine aminotransferase measurement QTL GWAS1262748 (human)3e-09serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)11183573811835739Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human

1 to 10 of 18 rows


1 to 10 of 10 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1226068_H GCST90310295 Diastolic blood pressure 1,028,980 European ancestry individuals A NR 8E-120 119.097 rs55857306 0.4744 diastolic blood pressure (EFO:0006336)
 PMID:38689001
GWAS1639173_H GCST90301698 Diastolic blood pressure 349,328 British ancestry individuals G NR 2E-44 43.699 rs55857306 0.04 diastolic blood pressure (EFO:0006336)
 PMID:38459180
GWAS1148094_H GCST007087 Systolic blood pressure approximately 422,000 European ancestry individuals ? NR 8E-89 88.097 rs55857306 N/A systolic blood pressure (EFO:0006335)
 PMID:30595370
GWAS1229799_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals A NR 3E-49 48.523 rs55857306 0.3444 pulse pressure measurement (EFO:0005763)
 PMID:38689001
GWAS1262748_H GCST90018943 Alanine aminotransferase levels 344,136 European ancestry individuals, 150,545 East Asian ancestry individuals A NR 3E-9 8.523 rs55857306 0.0158 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:34594039
GWAS1291590_H GCST90310294 Systolic blood pressure 1,028,980 European ancestry individuals A NR 5E-130 129.302 rs55857306 0.7957 systolic blood pressure (EFO:0006335)
 PMID:38689001
GWAS1383150_H GCST90446531 Hypertension 193,908 European ancestry cases, 265,230 European ancestry controls ? NR 4E-35 34.398 rs55857306 N/A hypertension (EFO:0000537)
 PMID:37947095
GWAS1411745_H GCST90435414 Diastolic blood pressure 404,337 European ancestry individuals ? NR 2E-56 55.699 rs55857306 0.0443823 diastolic blood pressure (EFO:0006336)
 PMID:39134668
GWAS1420413_H GCST90435415 Systolic blood pressure 404,507 European ancestry individuals ? NR 3E-73 72.523 rs55857306 0.0472741 systolic blood pressure (EFO:0006335)
 PMID:39134668
GWAS1558052_H GCST90449057 Diastolic blood pressure (MTAG) at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples) A NR 5E-103 102.302 rs55857306 0.04977938 diastolic blood pressure (EFO:0006336)
 PMID:39537608
1 to 10 of 10 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90310295 GWAS Catalog

Note Type Note Reference